GM2 ganglioside activator (GM2A:p) is a lysosomal co-enzyme that grabs some gangliosides so that β-hexosaminidase A can remove their HexNAc's. #proteomics
✔ 23 aa signal peptide + 10/11/12 aa propeptide;
✔ no significant PTMs;
✔ lots in urine; &
✔ AF structure with a phony signal/pro peptide.