alisonfeder.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Really excited about this new work from Sam Hart (and joint with @kelleyharris.bsky.social) trying to disentangle mutational differences between groups of cancers. Check out Kelley's thread with the major results!

submitted 1 day ago • 0 comments

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

submitted 8 days ago • 146 comments

I received a surprising and disturbing request from NIH on Friday. They wrote to cancel a subaward to Hong Kong on one of my grants. (This was disturbing but not surprising.) They also ordered us not to interact with our collaborators in Hong Kong on any work under the award:

submitted 24 days ago • 12 comments

Hearty congratulations to Anurag Agrawal, Amy Angert, and Graham Coop upon their election to the American Academy of Arts & Sciences, for their work illuminating the natural world around us. This recognition is very much deserved.

submitted 28 days ago • 0 comments

Interested in postdoc opportunities in Seattle, WA? Join us May 6th for Seattle DROP, a virtual event about biomedical research in Seattle. Hear from recruiting faculty, finding the right mentor and enjoy lunch on us via a delivery voucher within the US! Registration: tinyurl.com/seattledrop25

submitted 35 days ago • 1 comment

Add R25s to that list. Our NIH funding got straight up cancelled today for the two R25s that my team runs at Columbia for post-bacs and high-school students. I fear for our young scholars, who love learning about the brain and now are losing opportunities to be tomorrow's neuroscientists. 🧪

submitted 71 days ago • 5 comments

Pathogen genomes can provide insights into underlying disease transmission patterns but new methods are needed to analyze large genome datasets. Our work using identical pathogen sequences to characterize fine scale SARS-CoV-2 transmission was just published in @nature.com tinyurl.com/bdzk9xjj 🥳

submitted 77 days ago • 2 comments

📣Excited to share my last postdoc paper with @soumya-boston.bsky.social on eQTL mechanisms depending on where the RNA is in the cell! @broadinstitute.org @harvardmed.bsky.social TL;DR:Early RNA eQTL variants in the nucleus and late RNA eQTL variants in the cytosol have distinct molecular mechanism🧵

submitted 84 days ago • 2 comments

This is not news to most scientists by now, but others might be interested. Biomedical research is undergoing tremendous damage, even beyond the firings at NIH, CDC, and NSF; the suppression of data sharing; and the attacks on initiatives to improve scientific quality.

submitted 91 days ago • 1 comment

Measles infection can cause pneumonia or encephalitis, even death, soon after infection. What most folks don't know is that measles can also kill years later, from SSPE, subacute sclerosing pan-encephalitis. It's brain damage — incurable, irreversible, progressive, and nearly always fatal. 1/13

submitted 94 days ago • 12 comments

No job ad yet, but I'll be hiring a postdoc at Purdue in population genetics/quantitative genetics/genomics in plants. DM if you have relevant experience and are potentially interested.

submitted 95 days ago • 1 comment

In a new study led by Caelan Radford, we use deep mutational scanning to systematically compare the escape mutations from two broadly neutralizing antibodies in a clade A versus clade B HIV Envelope. www.biorxiv.org/content/10.1...

submitted 110 days ago • 2 comments

Genome Sciences is looking for a Grants Manager for the Model Organism Genetics labs (which include me!): uwhires.admin.washington.edu/ENG/candidat...

submitted 119 days ago • 0 comments

Hello world! I'm starting out on bluesky with a job posting - we're looking for lab research tech who shares our love of bugs. More info here brownlab.biology.gatech.edu/opportunities/

submitted 124 days ago • 1 comment

Oh yeah?

submitted 132 days ago • 2 comments

Very excited to have this paper officially out. This one is pretty special... Unfortunately, @kevinwoodum.bsky.social passed away when this paper was in its final stages. He was my biggest supporter, and I miss him deeply as a mentor and friend.

submitted 132 days ago • 2 comments

I think our preprint on mutation spectra and cancer evolution makes wonderful connections between theory and experiments in asexual bacteria and somatic evolution data from tumors. But we're struggling finding the right target journal. Any suggestions? doi.org/10.1101/2024...

submitted 156 days ago • 2 comments

Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵 www.science.org/doi/10.1126/...

submitted 160 days ago • 5 comments

After a long and winding odyssey, excited to finally drop anchor in open-access waters. This preprint shows how neutral allele frequency time series can illuminate disease transmission rates between communities— key for epidemic fore- & backcasting. medrxiv.org/content/10.1... 🧵

submitted 166 days ago • 1 comment

Do mutations that drive evolution improve many traits or few? Does this change over the course of evolution? Excited to share our work in PLOS Biology exploring these questions in the first 2 adaptive steps w/ Yuping Li, @gsherloc.bsky.social, @petrovadmitri.bsky.social 🧵 doi.org/10.1371/jour...

submitted 167 days ago • 1 comment

A careful dose of ignorance — a story of how my not reading two papers, many years ago, was vital to my career's path. waynemaddison.wordpress.com/2024/12/05/a...

submitted 167 days ago • 2 comments

New paper from the Olanrewaju Lab. We showed that we can measure HIV medications, including one used in recently approved long-acting injectable treatments, based on the drugs’ inhibition of viral DNA synthesis. Paper: doi.org/10.1007/s002... Preprint: doi.org/10.1101/2024... 1/5

submitted 174 days ago • 2 comments

I used paper by @alisonfeder.bsky.social @pleunipennings.bsky.social & @petrovadmitri.bsky.social in class yesterday. It makes v. useful point about softsweeps in viral time series. But its also v useful for motivating calculations on the probability of loss journals.plos.org/plosgenetics...

submitted 183 days ago • 2 comments

Hi friends new and old! I study how microbes interact and evolve in complex communities like the human gut microbiome.🦠🧬💩 I'm thrilled to share that I'm starting a lab at UC Irvine in April 2025 and am recruiting at all levels - please spread the word! kxuelab.com More about my work below...🧵1/n

submitted 183 days ago • 22 comments

Sharing again for new followers - check out this fully-funded postdoc to work with any Fred Hutch comp bio faculty members! Pre-apps due Dec 20 to start next year! www.fredhutch.org/en/research/...

submitted 184 days ago • 0 comments

For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site): thisweekmathonco.substack.com

submitted 185 days ago • 0 comments

Delighted to share that our paper on discovering selective sweeps with haplotype statistics in aDNA is now out in Nat. Comm! www.nature.com/articles/s41... Wonderful collaboration with Vagheesh Narasimhan, Devansh Pandey, and @mharris.bsky.social

submitted 189 days ago • 0 comments

I made a starter pack of folks affiliated with UW Genome Sciences (past and present) go.bsky.app/L8RAbiJ It's fairly sparse for now, so please let me know if you'd like to be added!

submitted 194 days ago • 4 comments

Having spent years building a network on twitter, I'm reluctant to start over, but I hear good things... I'm a scientist, I study viruses. I'll start by sharing some cool stuff we recently with published @eddieholmes.bsky.social and @jonathonmifsud.bsky.social www.nature.com/articles/s41...

submitted 195 days ago • 6 comments

I want to try something new at #ASHG24 this year: I'm going to block some time on Friday afternoon to meet with any trainees who would be interested to chat on any topic.

submitted 202 days ago • 1 comment

Looks amazing!

submitted 209 days ago • 0 comments

Sharing on behalf of Andy Clark @ Cornell. Their Dept of Mol Bio and Genetics has an Asst Prof opening with a focus on human genetics and genomics this year: academicjobsonline.org/ajo/jobs/28554

submitted 211 days ago • 0 comments

I wrote an essay about HIV drug resistance in pregnant women. Was fun to write. Hope you enjoy it! abetterscientist.wordpress.com/2024/10/22/e...

submitted 211 days ago • 0 comments

Are you a comp bio graduate student close to finishing your PhD? The Mahan Fellowship is a fully-funded ~2 year postdoc to work with any Fred Hutch comp bio faculty members! Pre-proposals are due Dec 20! Check out full details here: apply.interfolio.com/157470 #ScienceJobs 🧪 #AcademicSky

submitted 212 days ago • 0 comments

Taking a stab at a starter pack of Evolutionary Biologists — this was trickier than expected both because of the interface setup and because of the 150-person limit go.bsky.app/TUNHbNu

submitted 213 days ago • 14 comments

Tried to put together a Microbial Evolution starter pack, but there were so many great people I didn't want to leave out it turned into 3 starter packs Comment or DM me if you were missed or would like to be added! A thread (1/3) go.bsky.app/6pkuYhi

submitted 213 days ago • 27 comments

Uh oh @mossmouth.bsky.social

submitted 213 days ago • 0 comments

We have an open faculty search for TWO positions in microbiology and virology at the University of Illinois! We have world class core facilities and a fantastic collaborative group of young faculty...you could be next! Please re-post/skeet!

submitted 254 days ago • 1 comment