andrewplested.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Wonderful to present my work leading a large European consortium around @fmp-berlin.de and @eu-openscreen.bsky.social at #ELMI2025. We produce large-scale #open-source high quality Cell Painting data for drug discovery 💊. First dataset published: doi.org/10.1016/j.is... Stay tuned for more!

submitted 8 hours ago • 0 comments

I did my PhD in a section headed by Mary Lyon, and then went to UCL in a building that contained MRC Units directed by Ruth Sanger and Anne McLaren. They were all real supporters of other women - it was years before I realised how unusually lucky I was to have had such strong female role models.

submitted 8 hours ago • 0 comments

Oh dear. I just wrote to ~70 colleagues about our single moleucule biophysics course. 🤪 #Don'tLetThePerfectBeTheEnemyOfTheGood

submitted 8 hours ago • 2 comments

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology. Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at [email protected]. Fee waivers and bursaries available. ! Please share widely !

submitted 20 hours ago • 1 comment

📣 We are hiring a PhD candidate in computer-aided drug design with passion for MD simulations and ion channels to join our enthusiastic team at the University of Münster. For more details and information how to apply, please visit: uni.ms/j49p2

submitted 4 days ago • 0 comments

spent some time this evening updating the teamtomo.org site - if you're interested in cryo-EM + Python you might want to take a look around!

submitted 7 days ago • 0 comments

Nuts and bolts of brains, from brains. Don't miss Dr. Jia Zhou's EpIC seminar next Tuesday June 3rd at noon EST. Register for the series at sgp-epic-seminars.com - it's free and everyone is welcome. Please do spread the word!

submitted 9 days ago • 0 comments

Thank you @jcellsci.bsky.social, Sara Morais da Silva and Co for highlighting me as “cell scientists to watch”! It means a lot to me and I feel so honored as you guys are such a great community of amazing cell biologists! journals.biologists.com/jcs/article/...

submitted 9 days ago • 0 comments

At a time when many of us in science are reflecting on our place or path, the story of resilience shared by @kacarlab.bsky.social feels especially meaningful and deeply resonant.

submitted 9 days ago • 1 comment

It was an incredible experience helping shape the program of #COINs2025 in Gorizia, Italy. It felt like a family gathering, but rich with bold ideas. We discussed AI-powered society, sustainable future, and interspecies communication. gorizia25.coinsconference.org #CollaborativeInnovation 🧪

submitted 11 days ago • 1 comment

Love this station (it's Liege, on the Brussels-Cologne route), this short film, this whole idea. I never take my bike with me but always walk and/or run (for the same reason). In Milan recently, I was lucky enough to get a loaner bike and could see the city from the saddle - highly recommended!

submitted 11 days ago • 0 comments

Never read review articles is my advice.

submitted 12 days ago • 1 comment

DNA channel fluorescence intensity with overlaid object segmentation labels of chromosomes / cell nuclei in a zebrafish embryo. Acquired by Süheyla Eroglu-Kayikci on @visitech.bsky.social iSIM, labeled by student assistant Philip Kohle and rendered by PhD student Nils Friederich using @napari.org

submitted 12 days ago • 1 comment

These kind of giant commemorative “let’s rebuild our shattered land” plaques are very common in “East” #Berlin but I don’t think I’ve seen one “in the West” before- here near Reinickendorf. Are they rare or am I just sheltered in my OstBerlin bubble?

submitted 12 days ago • 0 comments

Good radio interview with Charité's dean Jochen Spranger, highlighting the lack of support by the local Government. He particularly points out how the illegal breach of existing financing contracts likely led to loss of excellent clusters. Cannot agree more. www.inforadio.de/rubriken/int...

submitted 13 days ago • 1 comment

The following message was sent by the journal on the date of 10 March 2025. You failed to receive this message, or intentionally you are not responding (sorry if I am wrong). Kindly request your immediate attention to this email and respond within 24 hours to end it smoothly. #AcademicSpam

submitted 12 days ago • 1 comment

Berlin’s local government is ruining the city’s scientific landscape, by further cuts into the under-financed Universities. www.tagesspiegel.de/wissen/kurzu...

submitted 13 days ago • 0 comments

I have no words to describe the amazing atmosphere at the 2025 #EMBOcellpol meeting! Thank you everybody for making this week science magic 🤩 see you all in 2027!!!

submitted 14 days ago • 0 comments

Non-profit journals are on the critical list. The cause: academics obsession with the Nature brand, coupled with the APC $ model. Some will argue it doesn’t matter (“all as bad as each other”). But the fact is undeniable and it’s good guys who put money back into science like COB who are losing..

submitted 14 days ago • 1 comment

🎉 We’re absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster! A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de #ClustersOfExcellence #SCALEcluster 🧵

submitted 14 days ago • 4 comments

Die #Exzellenzcluster stehen fest: Heute hat die Exzellenzkommission 70 Projekte zur Förderung ausgewählt. 45 Cluster werden fortgesetzt, 25 neu eingerichtet. Die Förderung beginnt ab 1. Jan. 2026 für 7 Jahre, die Fördersumme beträgt insg. 539 Mio. €/Jahr. Die Liste: www.dfg.de/resource/blo... 1/3

submitted 15 days ago • 2 comments

#Exzellenzstrategie: 💪 5 Berliner #Exzellenzcluster erhalten Förderung! @freieuniversitaet.bsky.social @humboldtuni.bsky.social @tuberlin.bsky.social #ChariteBerlin 👉 Zur Pressemitteilung: www.berlin-university-alliance.de/items/2025/2... #BerlinUAlliance #WirsindBUA #ExzellentimVerbund

submitted 15 days ago • 1 comment

Dear Andrew JR Plested, It's so nice to contact you through this email. We are in shortfall of one article for Successful Release of Volume 6 Issue 1 by 26th of May. Is it #AcademicSpam

submitted 18 days ago • 1 comment

Fantastic work from Alice Podesta to work through this puzzle. Be careful - NASPM inhibits NMDARs, and works better if you're not in voltage clamp. Happy to be part of this interesting study - we did the checks in heterologous cells. Shout out to @laetitiamony.bsky.social for her precious insight!

submitted 18 days ago • 1 comment

The polyamine naphthyl-acetyl spermine trihydrochloride (NASPM) lacks specificity for Ca2+-permeable AMPA receptors and suppresses seizure like activity in human brain tissue by inhibition of NMDA receptors. https://www.biorxiv.org/content/10.1101/2025.05.14.653650v1

submitted 18 days ago • 0 comments

This study shows a small effect on ADAR2 editing of GluA2 and a resulting change in cobalt uptake. I think it's hard to know what happens when you have a 5% reduction in Q->R editing, perhaps GluA2 (Q) substitutes GluA2 (R), maybe it substitutes GluA1/3 (Q). www.science.org/doi/10.1126/...

submitted 18 days ago • 0 comments

I had no idea samurai in feudal Japan were that dedicated to troubleshooting Flash

submitted 23 days ago • 45 comments

Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching. A collaboration with @mh123.bsky.social 🚀 github.com/danionella/w...

submitted 25 days ago • 7 comments

🧪 Congrats to the editors of the new Handbook of Electrophysiology, @scimemia.bsky.social, @nwanaverbecq.bsky.social, & @ianduguid.bsky.social, as well as my past postdocs @hovywong.bsky.social (now PI at CUHK) and Aurore Thomazeau (now PI at IPMC-CNRS France) to their two chapters in this book!

submitted 28 days ago • 1 comment

Sweeeeeet, the corresponding author is called 'Zuker' affiliated with the Zuckerman Institute!!!! 🧪 What else could they have worked on?!? 😂 First structures of human sweet receptor are mindblowingly beautiful!! 🍰🍭😍 And very inspired paper title... www.cell.com/cell/fulltex...

submitted 29 days ago • 0 comments

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

submitted 35 days ago • 7 comments

🎈Our latest 🪅 We know that in addition to exteroceptive mechanisms, interoceptive chemosensation is also critical for regulating physiology/behavior. We find that an enteric neuron in worms senses ingested salts via a variant ionotropic receptor (IR like the fly IRs) to regulate salt stress. 1/n

submitted 48 days ago • 7 comments

So the tired "preprints shouldn't be cited because they're not peer reviewed" meme is back. Reminder these frequently cited items aren't peer reviewed either: Editorials Books Reviews [some not all] News reports Data Code Websites Social media posts Citations are just links...intent varies 1/2

submitted 36 days ago • 6 comments

very few things make me as happy as data replication by different hands.

submitted 36 days ago • 2 comments

ChimeraX daily builds can predict small complexes of proteins, nucleic acids and small molecules using Boltz on your Mac, Windows or Linux computer without Nvidia graphics. www.rbvi.ucsf.edu/chimerax/dat...

submitted 36 days ago • 3 comments

Kaum jemand bringt die deutschen Verhältnisse so gut auf den Punkt wie Til Mette.

submitted 37 days ago • 7 comments

Trying to finish papers started by people who have since left the lab is a really painful exercise.

submitted 40 days ago • 11 comments

"Choose France for Science!" government cuts half a billion more to the research budget

submitted 41 days ago • 5 comments

Such an amazing, inspiring thread 🧪🧵

submitted 43 days ago • 0 comments

Very happy to announce a workshop I'm co-organising with Marion Silies and @crltt.bsky.social, taking place 2-4 Sept in Ingelheim, Germany! 'Flexibility and robustness of nervous system function', hosted by the Gutenberg Workshops @unimainz.bsky.social & with a fantastic line-up! Details below 🔻

submitted 43 days ago • 1 comment

Bonkers!

submitted 44 days ago • 0 comments

Read preprints. Cite preprints. Email people and tell them you loved their preprint. Email people you hated their preprint. Embrace preprints, preprints are good.

submitted 44 days ago • 7 comments

There is a lot I disagree with here but perhaps this most of all: “I’ve interviewed dozens of scientists who don’t know how to evaluate preprints, what they can trust, or what they can use in their own research.”

submitted 45 days ago • 10 comments

Super weird debris covered thing ‘walking’ on a diatom from the charles river, with another diatom attached to it, along for the ride. For the life of me could not make out what it was. #sciart #microscopy #plankton

submitted 45 days ago • 3 comments