brockhurstlab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Massive effort lead by the amazing @fabbenz.bsky.social to discuss the present and future of CRISPR-based antimicrobials ⚡

submitted 1 day ago • 0 comments

New opinion paper from the lab! www.cell.com/trends/micro...

submitted 1 day ago • 3 comments

That was fun: 2 days of bacterial genome evolution in beautiful Bath Ta @edfeil.bsky.social @eseb.bsky.social Great to see @craigmaclean.bsky.social @wtmatlock.bsky.social @jpjhall.bsky.social @taylorlabgroup.bsky.social @zaminiqbal.bsky.social @epcrocha.bsky.social @jomcinerney.bsky.social &co

submitted 1 day ago • 3 comments

CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferred https://www.biorxiv.org/content/10.1101/2025.05.09.653016v1

submitted 6 days ago • 0 comments

Lab mice (domesticated for >100y) have kept gut bacterial strains that codiversified w/ rodents for >25My. Here, authors show genetic drift occured in the lab, leading to loss of microb diversity+more deleterious mutations, impacting microbial fitness in lab vs wt mice www.nature.com/articles/s41...

submitted 71 days ago • 2 comments

We are seeing multiple instances of reviewers doing manuscript reviews via use of AI/LLM. If you don't want to do a review the old-fashioned way, better to decline the request. Giving someone else's manuscript to AI is a violation of intellectual property rights/laws; the manuscript isn't yours...

submitted 4 days ago • 11 comments

Diversity Between but Not Within Microbial Communities Increases With the Diversity of Supplied Nutrients https://www.biorxiv.org/content/10.1101/2025.05.10.653264v1

submitted 5 days ago • 0 comments

I really enjoyed contributing to this perspective on how to use routine clinical data for AMR surveillance, with @katholt.bsky.social, @gmknght.bsky.social, and the @lshtmamrcentre.bsky.social management team! www.nature.com/articles/s44...

submitted 5 days ago • 2 comments

Our opinion piece on transmission timing in phages and plasmids graces the cover of @cp-trendsmicrobiol.bsky.social this month. Featuring the work of talented master student Andrina Bernhard, the illustration showcases cues that MGEs use to switch between horizontal and vertical transmission.

submitted 7 days ago • 2 comments

1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below. shorturl.at/o6S1w

submitted 7 days ago • 1 comment

When things add up: environmental structure and microbial interactions drive antibiotic-resistance plasmid evolution. New paper from the lab, and the third chapter of Lars Zandbergen’s thesis! www.biorxiv.org/cgi/content/...

submitted 8 days ago • 2 comments

New Research Assistant position available in my lab to work on a project testing the efficacy of pills dependent #phage against clinical isolates of enteric bacteria . Part of a growing phage research theme in my lab my.corehr.com/pls/uoxrecru...

submitted 7 days ago • 2 comments

🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉 Short 🧵 www.science.org/doi/10.1126/...

submitted 7 days ago • 15 comments

Q: What happens when a #PublishOrPerish" research culture meets #AI readable biomedical databases? A: "An explosion of formulaic research articles, including inappropriate study designs and false discoveries." New in @plosbiology.org... journals.plos.org/plosbiology/...

submitted 7 days ago • 0 comments

May’s ‘Microbe of the Month’ is a novel archaeon called Methanobrevibacter intestini which was isolated from a human faecal sample taken from an individual in the United States. Find out more about M. intestini and other exciting discoveries by clicking the link in our bio 🧫🔬

submitted 8 days ago • 1 comment

#phage #phagesky 😮

submitted 9 days ago • 0 comments

Wow www.biorxiv.org/content/10.1... A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome

submitted 9 days ago • 4 comments

Having recently read >500 applications for recent hirings, AI CVs are a fast growing problem Giveaways are summaries eerily matching the job spec (but bearing little relevance to the rest of the CV) & weird generic phrases like “detail orientated” no-one says Tell your mentees/classes to avoid!

submitted 10 days ago • 3 comments

📣 Imperial College Research Fellowships! Prestigious 4yr fellowship ✔️ Salary from £48k ✔️ Up to £45k for research ✔️ A supportive, inclusive research environment ✔️ UK or international ✔️ <4 yrs post-PhD Drop me a pm if you are interested in bee/microbe related research! tinyurl.com/mr3k5a93

submitted 10 days ago • 0 comments

How do vaccines work? Prof @robinmay9.bsky.social explains how #vaccination changed the world, saving millions of lives and enabling us to eradicate a lethal disease for the first time in human history... Watch full lecture: gres.hm/how-vaccines #immunology #vaccine

submitted 13 days ago • 0 comments

Highlights how the AMR crisis is also a cancer research issue Redirecting just a tiny fraction of cancer research funding to AMR would be transformative

submitted 12 days ago • 1 comment

⏰ Only 2 Days Left! ⏰ This is it: your last chance to submit your abstract for hashtag#ESEB2025! Don’t miss the opportunity to showcase your research and be part of one of the most important events in Evolutionary Biology. 📬 Submit now: https://eseb2025.com/call-for-abstracts/

submitted 13 days ago • 0 comments

Good Pseudomonas aeruginosa comparative genomics study by @reeskassen.bsky.social &co journals.asm.org/doi/10.1128/...

submitted 12 days ago • 0 comments

New post on the challenges of communicating uncertainty - and the lengths people will go to in an effort to avoid being pinned down… kucharski.substack.com/p/possibly-a...

submitted 13 days ago • 1 comment

Today is the day - #NoMowMay is here! Ready to start your #NoMowMovement and help nature? 🌸🥳 & remember, this is just the start...leaving wildflowers to grow in the summer helps biodiversity & local wildlife. 🦋 Join & give #PowerToTheFlowers 👉 bit.ly/3UWii6B

submitted 15 days ago • 0 comments

We are pleased to announce that registration for 3rd MGE Workshop is now live! If you are interested in giving a talk please register online through our website by Friday 16th May. We look forward to seeing you all in Southampton in June! www.ukmgeworkshop.org

submitted 15 days ago • 1 comment

Come join us in Southampton! You need to register to participate (free registration!). To give everyone an opportunity to showcase their science, we extended the deadline for title submission to May 16. Share widely!

submitted 14 days ago • 1 comment

The evolution of robustness and fragility during long-term bacterial adaptation #mevoSky #evoSky #evolSky #evolution #ExperimentalEvolution #LTEE www.pnas.org/doi/10.1073/...

submitted 24 days ago • 0 comments

#Mevosky

submitted 14 days ago • 0 comments

Another great looking meeting for UK #Mevosky aficionados June 16-17 with socials on 15 June in Southampton Homebrewed and low £cost (Excellent logo too…) www.ukmgeworkshop.org

submitted 14 days ago • 0 comments

This meeting will be great! Abstract submission open now See you 26-27 Nov in Liverpool microbiologysociety.org/event/societ...

submitted 16 days ago • 2 comments

Fresh in @NatureBiotech! We developed a synthetic biology tool for tracking gene transfer in microbial communities and applied it to study plasmid hosts in a wastewater microbiome. Awesome collab with James Chappell & @joffsilberg.bsky.social and incredible students. www.nature.com/articles/s41...

submitted 58 days ago • 3 comments

www.sciencedirect.com/science/arti... Nearly missed my bus stop reading this fascinating review :)

submitted 19 days ago • 1 comment

Junior faculty job alert in Germany - Marine Evolutionary Genomics @geomarkiel.bsky.social / University of Kiel www.geomar.de/en/karriere/... Marine study system of your choice (no microbes, sorry…), excellent infrastructure and ship access, moderate teaching requirements, closing date 6 June

submitted 19 days ago • 1 comment

PhD opportunity in St Andrews on plasmids, antibiotics and defence systems, in collaboration with Helen Alexander in Edinburgh. Funding via BBSRC EastBio, please share & pass on to anyone interested! #microsky🦠🧫🧬 www.findaphd.com/phds/project...

submitted 155 days ago • 0 comments

Antibiotics are life-saving, but even short use can drive resistance in gut bacteria, with mutations lasting over a year, as seen here for ciprofloxacin. Antibiotic stewardship helps protect these powerful drugs for the future. #AMR #OneHealth #AntibioticResistance www.nature.com/articles/s41...

submitted 22 days ago • 0 comments

Great work from Ana Victoria and team! I'm not surprised #prophages are involved and happy to contribute to a fabulous study. doi.org/10.1099/mgen...

submitted 24 days ago • 0 comments

A huge, new resource for plasmid research - PlasmidScope is a database of 852,000 #plasmid sequences with a rich set of annotations, automated online analysis and interactive visualisation academic.oup.com/nar/article/...

submitted 24 days ago • 4 comments

Engineering bacteriophages through deep mining of metagenomic motifs www.science.org/doi/full/10.... #jcampubs

submitted 24 days ago • 0 comments

New paper @isme-microbes.bsky.social : Among a sample of 1044 vibrio phages, we found 17 new Schizotequatrovirus with large genomes (>250kb), a broad host range, and yet a low frequency in our samples (?!). #MicroSky #PhageSky

submitted 32 days ago • 4 comments

I am thrilled to share the first manuscript from the Wiles lab! We present "Phollow", an in vivo phage-tagging approach that enables direct observation of phage outbreaks with single-virion resolution by live imaging. Here some highlights 👇 www.nature.com/articles/s41...

submitted 27 days ago • 5 comments

1/ In our new paper, we explored whether obligate mutualisms can survive abrupt stress via evolutionary rescue. We found that evolutionary rescue is possible—but it comes at the cost of mutualism. @jfriedman.bsky.social #microsky #evosky #mevosky

submitted 32 days ago • 1 comment