caffalette.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

The amazing Sofia Lövestam initiated the below project, when she became interested in the vault particles that we sometimes observe in #cryoEM images of brain-derived #amyloid filaments. www.biorxiv.org/content/10.1...

submitted 23 hours ago • 2 comments

This isn’t just numbers on a table–it’s my lab and the labs of my colleagues. Terminated grants mean shuttered projects, lost talent, and stalled progress against deadly pathogens. The damage to science–and to public health–is real and immediate. Thanks @peterhotezmdphd.bsky.social for speaking out.

submitted 5 days ago • 0 comments

Back to @mblscience.bsky.social Woods Hole - teaching on the Pair Up Microscopy Course. Great experience and awesome participants. Wild - last time here I was a student (Physical Biology of the Cell Course in 2018). Now introducing my lab. Thanks Abhishek Kumar for organising and the invitation.

submitted 10 days ago • 1 comment

If people of means are interested in establishing a 2025 “Institute for Advanced Study” for displaced/defunded biomedical scientists, I know many people who will help, including myself. @mcuban.bsky.social @arcadiascience.com @arcinstitute.org

submitted 10 days ago • 4 comments

Here’s another spectacle of New York spring entomology: Eastern tent caterpillars (Malacosoma americanum) are among the most social lepidopterans. In May, you can find their silken tents, in which they aggregate (and defecate).

submitted 23 days ago • 1 comment

My lab at NYU is hiring a postdoc interested in RNA biology and local translation in neurons following axonal injury/neurodegenerative diseases!! Apply here: apply.interfolio.com/165681

submitted 28 days ago • 0 comments

Tomorrow at the Systems Virology Journal Club, @tamanash.bsky.social will present his beautiful work with @harmitmalik.bsky.social on optimizing temperature-dependent trade-off between protein production and processing in alphaviruses through stop codon selectivity pubmed.ncbi.nlm.nih.gov/40249804/

submitted 28 days ago • 0 comments

Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...

submitted 55 days ago • 2 comments

Rachael, thank you for this. We can all benefit from the example of your courage and wisdom in speaking out.

submitted 61 days ago • 1 comment

Structural insights into the coupling between VCP, an essential unfoldase, and a deubiquitinase. New study from Lauren Vostal, Tarun Kapoor and colleagues @rockefelleruniv.bsky.social: rupress.org/jcb/article/... #StructuralBiology #Biochemistry #ProteinHomeostasis #CryoEM

submitted 68 days ago • 0 comments

WE GOT THE COVER!!!

submitted 69 days ago • 5 comments

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉 You can find the full story here www.science.org/doi/10.1126/... @verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

submitted 69 days ago • 12 comments

Proud that one of my photographs has made the cover of Cell. (first 'official' photograph publication) Very happy to contribute the pic and highlight the latest publication of the Ruta lab.

submitted 69 days ago • 8 comments

In preparation for the lecture tomorrow, I opened "The Cell in Development and Heredity" by E.B. Wilson (Columbia Univ), and realized that this 3rd edition was published in 100 years ago. So many things happened since then, including the fact that I, a Japanese Prof in NY, own and read the book.

submitted 77 days ago • 1 comment

Fantastic #TeamTomo story on retrotransposon particles by @svenklumpe.bsky.social and friends. Take a look! 🧪🧶🧬

submitted 84 days ago • 0 comments

Retrotransposon-derived capsids in the Dros. ovary revealed by CryoET! Amazing PhD work by @svenklumpe.bsky.social (still MPI Biochemistry) in collab with @juliusbrennecke.bsky.social lab - congrats to all authors! Really looking forward to exciting times with Sven @viennabiocenter.bsky.social!

submitted 84 days ago • 0 comments

This has to be one of the coolest papers of the year: retrotransposon VLPs, visualized inside cells! #TeamTomo #CryoET

submitted 84 days ago • 1 comment

Congrats to our postdoc Jan-Hannes Schaefer @jhschaef.bsky.social on being awarded a fellowship from the Walter Benjamin Program! Jan is collaborating with the Kelly lab here at Scripps Research @scripps.edu to understand how transthyretin forms amyloids that lead to heart disease.

submitted 86 days ago • 0 comments

Hey #chemsky and beyond, with all that is going on, I am curious what expensive, high margin molecules we could provide to the community for free. What things do you use all the time, cost way too much, and would make a difference? Alexa Fluor 488 NHS? Other dyes? Other molecule?

submitted 88 days ago • 7 comments

Beautiful story on HIV-1 Matrix maturation and seeing it out in complete story by my postdoc colleagues James and Dominik from the Briggs group @briggsgroup.bsky.social Congratulations to all!

submitted 89 days ago • 0 comments

we recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓) We decided to call them TIGR-Tas systems 🐯

submitted 89 days ago • 2 comments

Thanks to everyone for coming out in solidarity today in New Haven despite the chilly temperatures. Props to the speakers for sharing their stories and experiences. Onward! @valeriejhorsley.bsky.social @aaup.bsky.social #labor4highered

submitted 98 days ago • 0 comments

The Democratic staff of the Committee on Science, Space, and Technology is surveying the impact of the mass firings of federal employees from science agencies. democrats-science.house.gov/sciencefirings

submitted 98 days ago • 0 comments

We had a great @aaup.bsky.social HANDS OFF rally today in New Haven CT! Thx to coorganizer @luskinglab.bsky.social and all of our speakers! When we fight, we win!

submitted 98 days ago • 0 comments

Thanks. You folks are the primary things that keeps me motivated to fight as hard as I effing can. This system greatly enriched my life and my ability to contribute, and others deserve the same opportunities.

submitted 98 days ago • 2 comments

Good news! The website for the Yale Chapter of @aaup.bsky.social just dropped: aaupyale.org Just in time to help make a difference. ❤️‍🩹

submitted 100 days ago • 0 comments

Cultural revolution in the US. Elevation of ignorance and empowerment of the ignoramus. Large scale, capricious upheaval of core government functions. This is likely to lead to illness, hunger and poverty for many.

submitted 103 days ago • 0 comments

My heart goes out to all my NIH people. Unbelievable.

submitted 103 days ago • 0 comments

Excited see the final portion of my PhD work with Vanessa Ruta out today in @cellpress.bsky.social, in the midst of everything. In time for valentines day, @rufeili.bsky.social and I describe how competition between males sculpt mating decisions in 🪰🫶. www.cell.com/cell/fulltex...

submitted 104 days ago • 5 comments

So exciting! It makes me so happy to see a round of private funding toward preserving the magical place that MBL is!

submitted 112 days ago • 0 comments