chriswheat.bsky.social
Ecological & Evolutionary Functional Genomics, mostly butterflies. Biology Professor, Stockholm University.
59 posts
1,835 followers
367 following
Prolific Poster
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Really great to see this out. Congrats to team!!!
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Awesome, what’s the time frame? Y’all ok w some poolseq data?
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It is sad that even basic research needs to be defended with utility. For me, basic research is in the same category as art: civilized societies can't do without it, because we all want to know who we are and what our place in the natural world is -- questions that only science can answer.
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www.theguardian.com/us-news/2025...
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Adaptive LOF likely explains why much of the pan genome is not within the core!
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I think it falls also under the general lack of awareness that adaptive evolution through LOF is incredibly common, especially given background rates of gene duplications, or re-diploidization after WGD, or even the evolution of gene regulation (eg loss of TFBS, miRNA bonding sites).
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And should we follow the Conservation Genomics crowd and view LOF alleles as deleterious?
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Exactly that.