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davidmartinez.bsky.social
Assistant Professor of Immunobiology and Microbial Pathogenesis at Yale University School of Medicine. Hanna H. Gray Faculty Fellow of the HHMI. Scientist. Husband/Dad. Viral pathogenesis. Vaccines. Immunobiology. Above all, be kind.
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🙌🏼 praise be for the judicial branch putting the brakes on the illegal actions of this current administration. Judge Rules N.I.H. Grant Cuts Illegal, Orders Funds Restored www.nytimes.com/live/2025/06...

Real vaccine science, check it out

A paper from our pancoronavirus vaccine P01 grant group is now out in Science Translational Medicine. Here we show that non-stabilized spike delivered as mRNA is sufficient to elicit broadly neutralizing antibodies in monkeys. @alexschaefer.bsky.social www.science.org/doi/10.1126/...

Kennedy’s ACIP 2.0 is as expected. Headlined by charlatans that have nothing to lose and will rubber stamp ludicrous policies. I strongly urge my fellow healthcare providers to speak up and be unafraid. We must ensure there is accountability through collective action.

The process for ACIP membership usually takes years of vetting, particularly for conflicts of interest. Have these people undergone the same level of scrutiny? I'm pretty sure Malone has made money from saying falsely that mRNA vaccines are unsafe.

RFK Jr.’s attack on vaccine experts endangers every American www.statnews.com/2025/06/10/a... via @statnews.com "Kennedy is not fit for the office he holds." "Congress must act. The medical and public health community must speak out. And the public should demand better."

www.nature.com/articles/d41...

~40% cuts to NIH research awards. ~35% cuts to training programs. ~27% cut to internal research. ~30% fewer grants awarded overall. The Common Fund will be cut in half. American science has never faced a threat like this. www.statnews.com/2025/06/06/n... via @statnews.com

Remember the day when the cyber truck was unveiled by Elon Musk trying to channel his best Steve Jobs? When he took a hammer to the ‘bulletproof windows’ which were not? Today is better.

Losing the US contribution to GAVI is predicted to lead to 1.2 million additional preventable child deaths globally. From our new piece about measles: www.nature.com/articles/s41...

I grew up in the US in the 1980s, so exceptionalism is a defining trait. My default setting is USA #1. I can’t accept that making America great again means voluntarily stepping off the podium and relinquishing our medals. It’s the least American thing we could ever do.

RFK has always a history of making his own reality which requires making stuff up to support his fantasy-reality

🚨 In a stunningly short-sighted move, HHS just canceled its contract with Moderna to test mRNA vaccines for #H5N1 and other pandemic threats. When the next big outbreak hits, what’s the plan—bleach again? This will come back to bite us. Hard. #BirdFlu #PublicHealth #PandemicPreparedness

New paper about ACE2 using Merbecovirus. Hot stuff. So hot but you can't Letko. @fviromics.bsky.social and Nick Catanzaro. www.nature.com/articles/s41... #ACE2 #emergingviruses #bats #batman #MERS #HKU5

Definitely fool’s gold. Pun intended.

Our study screening the majority of all published Merbecovirus RBD’s for cell entry phenotypes is now published in Nature Communications! (1/5) shorturl.at/gYz4E

3 guys, none with infectious disease or pedatric expertise, just ran roughshod over normal procedures to block COVID shots for kids, pregnant people. This is so awful & insane & we should treat it as such. Reporters, you're on notice. Both sides this at your peril & watch your credibitlity evaporate

ACOG is deeply disappointed by HHS’s move to drop COVID-19 vaccine recommendations in pregnancy. The science is clear: COVID-19 remains dangerous in pregnancy and vaccination protects both patients and newborns. The vaccine is safe and protects families. Read our full statement: buff.ly/OGue7sO

"During his confirmation hearings, Kennedy assured lawmakers he would not take away anyone’s vaccines. But removing the vaccine from CDC’s recommended list will have a similar impact." thehill.com/policy/healt...

This is one of the dumbest health policy decisions I have ever seen.

Covid was a gift to republicans to strategize & use it to the fullest to create a foundation to kill health agencies - countless disinfo spreading non-profits, summits, studies & journals, podcasts, social media campaigns, congressional hearings, etc. A great piece by @walkerbragman.bsky.social

Breaking News: A judge blocked a Trump administration move to bar Harvard University from admitting international students, hours after the school filed suit.

This story is finally out! Deletion of E from some coronaviruses abolishes virus production & infectivity (MERS-CoV). Deletion in others merely attenuates replication (SARS-CoV). Turns out SARS2 is like SARS1. We asked how a virus can tolerate removal of a structural protein involved in 1/

Sooooo… ICE now has a bigger budget than the NIH which funds almost all of the biomedical research in America. This is precisely where the priorities of this administration lie.

(1/2) Under 65 with no risk factors? Congrats, you're now a COVID-19 Hunger Games tribute. May the odds be ever in your favor. 🎯 www.theguardian.com/us-news/2025...

If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.

Calling all virologists: my lab is hiring a tech for high containment work! Come work with our amazing team at 🇨🇦's National Pandemic Research Centre, using experimental, systems biology, & AI-driven approaches to study infection & pathogenesis of emerging viruses.

Exciting study on infant immune responses to sars-cov-2 and how they compare to adults.

All 4 of my NIH research grants are terminated. These were grants on MDR-TB treatment & strategies for supporting adolescents living w/ HIV. This is a massive waste of resources. I am heartbroken for my Harvard team, my partners in Peru, the next generation of scientists & our country. Shame.

So this is not a problem?...But we can't even buy an NIH researcher a cup of coffee because of conflicts of interest!? The hypocrisy is insane. Investigations into universities, but at the White House all gifts and straight up crypto-bribes are fine. WTF www.nytimes.com/2025/05/11/u...

www.nature.com/articles/s41...

How dengue defies dogma: An extrafollicular tale www.science.org/doi/10.1126/...

New commentary by stellar student in my group @jordanpolster.bsky.social is now out in Science Immunology! www.science.org/doi/10.1126/...

3 more states report their first #measles case of 2025. At least 27 states have reported cases of measles as it spreads. abcnews.go.com/Health/3-sta...

When you scan the email from the editor and spot the words "accepted in principle"

After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors. www.nature.com/articles/s41...

Harvard steps up www.harvard.edu/research-fun...

Our study on the molecular basis of shifts in receptor recognition by western equine encephalitis virus (WEEV) in the past century, led by Xiaoyi Fan and @wanyuviridae.bsky.social , is online! 👏🎉 www.cell.com/cell/fulltex...

Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.

Yesterday was one of the darkest days in NIH history, all because Jay Bhattacharya was so outraged that he was criticized for a shitty serology study that he went all in on burning it all down. www.scientificamerican.com/article/nih-...

Carnage. www.nature.com/articles/d41...

Started/Going. Two infants died of pertussis in Louisiana, where last month the state’s surgeon general banned health department staff from encouraging vaccination.

...a “pointless, ill-advised move that will hurt U.S. science and pandemic readiness,” says Charles Rice, a Nobel Prize–winning virologist at Rockefeller University www.science.org/content/arti...

I got the news this morning on two COVID related grants that were being terminated because its no longer seen as a research priority by Health and Human Services. My people have been given their notice. I have no words to express my feelings. www.nbcnews.com/health/healt...

The damage being done to the biomedical community will probably not be appreciated for years