evanirvingpease.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

🆕 The "Machine learning of spatial data" section is now live on the CRAN Spatial Task View! 🌍 Check it out at https://cran.r-project.org/view=Spatial Have suggestions or improvements? Contributions are welcome!💡 #rstats #rspatial #MachineLearning #gischat

submitted 7 days ago • 0 comments

The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples

submitted 9 days ago • 0 comments

devastated to discover Cheddar Man was lactose intolerant

submitted 9 days ago • 30 comments

Celtic languages are now limited to NW Europe, but they were once far more widespread. How did they spread? I'm excited to have contributed to this new ancient DNA study led by @hmcccoll exploring exactly that. 🧬 1/n www.biorxiv.org/content/10.1...

submitted 12 days ago • 1 comment

A common sentiment is “I can’t share my code because it’s messy and there might be errors” But if it’s that untrustworthy, why are you publishing the results it generates?

submitted 12 days ago • 3 comments

Delighted to see our paper on the evolutionary history of the CCR5Δ32 deletion published this week in @cellpress.bsky.social. Work led by @ravnkirstine.bsky.social, Leonardo Cobuccio and Rasa Muktupavela, and co-supervised by me and @simorasmu.bsky.social. See 🧵 for main findings...

submitted 14 days ago • 2 comments

Super excited to share my latest preprint with @klohmueller.bsky.social! Here we leverage the unique signature that recessive deleterious variants can lead to an increase in archaic ancestry to tackle a classic question - the dominance distribution on the human genome www.biorxiv.org/content/10.1...

submitted 13 days ago • 2 comments

Delighted to see our paper on the evolutionary history of the CCR5Δ32 deletion published this week in @cellpress.bsky.social. Work led by @ravnkirstine.bsky.social, Leonardo Cobuccio and Rasa Muktupavela, and co-supervised by me and @simorasmu.bsky.social. See 🧵 for main findings...

submitted 14 days ago • 2 comments

Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n

submitted 19 days ago • 57 comments

Excited to share our study on and with Picuris Pueblo! It’s a true honor to have worked alongside the community. Combining oral history and genomics, we show a long-standing continuity in the US Southwest and challenge ideas of pre-Columbian population collapse. www.nature.com/articles/s41...

submitted 16 days ago • 3 comments

Ancient and present-day genomes from members of the Indigenous American tribe Picuris Pueblo in the US Southwest show genetic continuity with Ancestral Pueblo individuals from the Chaco Canyon, New Mexico. https://go.nature.com/4cWV2Os

submitted 20 days ago • 1 comment

@evanirvingpease.bsky.social exploring the evolutionary origins of diseases. MS genetic risk rose among Steppe pastoralists & was brought into Europe by migration ~5kya. These MS-associated immunogenetic variants underwent positive selection, likely driven by pathogenic challenges. #HumanEvo25

submitted 22 days ago • 0 comments

Great start to final mirning if #HumanEvo25 by @evanirvingpease.bsky.social 🤩Major insights gained by using European & W Asian ancient genomes to establish stratified ancestries that shaped current European 🧬 pool through Ancestry-specic selection. Focus on #HLA, MS & other immune loci

submitted 22 days ago • 0 comments

We are pleased to announce that the early bird registration deadline has been extended to May 7th! www.isba11.com/registration/ #archaeology #biomoleculararchaeology #ISBA11 #archaeologists @archaeobiomics.bsky.social @isbarchaeology.bsky.social

submitted 27 days ago • 0 comments

Deadline for expressions of interest to join the ISBA board close tomorrow. This is your opportunity to help shape the direction of the society!

submitted 27 days ago • 0 comments

Nominations are now open for the ISBA Distinguished Article Award! ISBA members are encouraged to nominate their own articles for these awards or those of others. Deadline for nominations is 29th June and the winners will be announced at ISBA11 docs.google.com/forms/d/e/1F...

submitted 44 days ago • 0 comments

Nominations are now open for the ISBA Outstanding Publication Student Prize! ISBA members are encouraged to nominate their own articles for these awards or those of others. Deadline for nominations is 29th June and the winners will be announced at ISBA11 docs.google.com/forms/d/e/1F...

submitted 44 days ago • 0 comments

A final request for those involved in the Ancient Biomolecule Communities: If you follow the activities of AaRC, HAAM, PAASTA, SPAAM and LAARD, help us improve our understanding of our communities with this short survey! #aDNA #palaeoproteomics #biomoleculararchaeology #ZooMS #ancientDNA

submitted 44 days ago • 1 comment

submitted 43 days ago • 8 comments

Register now to get the early bird rate for ISBA11! isba11.com/registration/ #archaeology #biomoleculararchaeology #ISBA11 #archaeologists @isbarchaeology.bsky.social @archaeobiomics.bsky.social

submitted 47 days ago • 0 comments

Would your institution like to host ISBA12? We are inviting expressions of interest from ISBA members to host the next ISBA12 symposium in 2027. Please contact the ISBA board ([email protected]) for application requirements. Applications are due by the 25th May 2025.

submitted 44 days ago • 0 comments

Would you like to help shape the future of ISBA? We are taking expressions of interest to become a trustee of the International Society for Biomolecular Archaeology. Nominations are open for members at any stage of their career! The deadline is the 26th April 2025 docs.google.com/forms/d/18jx...

submitted 44 days ago • 0 comments

A funded PhD at Aberdeen, forming part of @whatkatiedigs.bsky.social’s ERC funded project on Late Glacial Scotland. Application deadline April 13: www.findaphd.com/phds/project...

submitted 80 days ago • 0 comments

We have a 4-year PhD-student opening in our lab, deadline on Wednesday noon. For anyone interested in computational genomics of ancient human, pathogen, or canid genomes. www.crick.ac.uk/careers-stud... If you are curious, send in an application!

submitted 65 days ago • 0 comments

Job alert! @katerinad.bsky.social and I are looking for an archaeologist/archaeological scientist to join us on a 4 year post-doc, helping to manage and participate in field and lab work on 2 ERC grants in our group. We would love to hear from you via the link! 👇 jobs.univie.ac.at/job/Postdoct...

submitted 71 days ago • 4 comments

Our scientific committee is busy evaluating your abstracts. In the mean time, registration for ISBA11 is now open! For the special early bird discount, make sure to register by April 30, 2025! www.isba11.com/registration @isbarchaeology.bsky.social @archaeobiomics.bsky.social

submitted 78 days ago • 0 comments

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

submitted 71 days ago • 55 comments

Heritability = one of the most commonly confused concepts in public (mis)understanding of genetics. Let’s break it down. Imagine studying a cohort of people in a specific set of environmental circumstances. You assess everyone for an observable trait & find it varies from one person to another. 🧪1/5

submitted 73 days ago • 4 comments

We finally have some well-powered whole-genome heritability estimates, including a quasi-behavioral trait (BMI). For height, ~89% of the heritability estimated to reside in common variants. For BMI and WHR, ~100% estimated in common variants. www.biorxiv.org/content/10.1...

submitted 84 days ago • 1 comment

Once upon a time, in the late 1800s, people in Japan got really into breeding mice. Coloured mice. Patterned mice. Even mice that danced. They became known as Japanese Fancy Mice, and that caught the attention of researchers in Europe and America, who imported them for study. 2/n

submitted 78 days ago • 20 comments

(1/9) I’m hiring! Join my ‘Terraform’ ERC project at the University of Malta, looking at the origin, evolution, and impacts of agricultural terracing in the Maltese Islands. Please circulate to anyone you think could be interested. Starting in the summer.

submitted 86 days ago • 1 comment

Abstract submissions are still open by 4 March for our #HumanEvolution conference! Don’t miss the chance to join our amazing speakers! @sarahpederzani.bsky.social @paleogenomics.bsky.social @amygoldberg.bsky.social @jjrowan.bsky.social @martamlahr.bsky.social @evanirvingpease.bsky.social

submitted 91 days ago • 1 comment

Showcase your insights from #archaeology, #palaeontology, or #PopulationGenetics at our 2025 Human Evolution conference! #HumanEvo25 Support peers to bridge knowledge gaps between #AncientDNA and modern #genomes. ⏰Build your research profile - submit an abstract by 18 February 📎 bit.ly/4ajmLI6

submitted 106 days ago • 0 comments

Think of a polygenic score you care about. Are direct genetic effects driving variation among people in this predictor? Or perhaps other, confounding factors? We at the @arbelharpak.bsky.social & @docedge.bsky.social Labs developed a method to tackle this question. [1/n]

submitted 106 days ago • 2 comments

Thread and open access version to come- Ancient genomics and the origin, dispersal, and development of domestic sheep | Science search.app/gtSKYHF5HqRa... #adna

submitted 111 days ago • 6 comments

The ISBA11 abstract submission deadline is quickly approaching! Submit now before its too late! The final day to submit your abstract is January 31st, 2025! #archaeology #biomoleculararchaeology #ISBA #ISBA11 #archaeologists @isbarchaeology.bsky.social @archaeobiomics.bsky.social

submitted 112 days ago • 1 comment

🔊Calling all School of Archaeology staff, students, projects and alumni! So far I've found 27 of our School community on here, let us know if there are more! go.bsky.app/JX5CP1k

submitted 126 days ago • 3 comments

How population stratification makes environments look like genes. A short 🧵:

submitted 121 days ago • 7 comments

You asked and we listened! The ISBA11 abstract submission deadline is extended to January 31st! Submit your abstract before time runs out! www.isba11.com/abstract-sub... #archaeology #biomoleculararchaeology #ISBA #ISBA11 #archaeologists @isbarchaeology.bsky.social @archaeobiomics.bsky.social

submitted 125 days ago • 1 comment

A reminder of the aDNA feed - follow it! and for inclusion use #aDNA, #aRNA, #sedaDNA, #Palaeoprot or #AncientGenomics bsky.app/profile/did:...

submitted 154 days ago • 0 comments

I just discovered this brilliant talk by Dr. Audrey Lin (@undeaddandy.bsky.social) on ancestry & cultural importance of Coast Salish woolly dogs. youtu.be/_GSj8aKPAuE?... #bioarchaeology #zooarchaeology #evolutionarybiology #aDNA 🏺 🐕. Thanks to @archsw.bsky.social for making this publicly available.

submitted 154 days ago • 1 comment

1) Postdoc job opportunities…join my TerraForm ERC project, at the University of Malta. One position for a geoarchaeologist and one in GIS/spatial analysis. The formal advert and application procedure will be out soon (and shared here), so I am releasing this as an early notice.

submitted 153 days ago • 3 comments

What do GWAS and rare variant burden tests discover, and why? Do these studies find the most IMPORTANT genes? If not, how DO they rank genes? Here we present a surprising result: these studies actually test for SPECIFICITY! A 🧵on what this means... (🧪🧬) www.biorxiv.org/content/10.1...

submitted 156 days ago • 4 comments

A surprising (to me) result! Polygenic score portability across groups does not improve if based on within-family GWAS, which accounts for most forms of environmental confounding. Suggests genetic architecture is main driver and shows within-family GWAS aren't a solution to poor PGS transferability.

submitted 156 days ago • 1 comment

In this comment piece with James Fellows Yates and Christina Warinner (@christinawarinner.bsky.social), we highlight the mounting problems with data archiving and metadata reporting in ancient DNA research. The field cannot afford to keep neglecting this issue. www.nature.com/articles/d41...

submitted 162 days ago • 0 comments