febrigunawan48.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Mars: simplifying bioinformatics workflows through a containerized approach to tool integration and management academic.oup.com/bioinformati... 🧬🖥️🧪 github.com/GenomicAI/mars

submitted 10 days ago • 0 comments

NIH PostBac program is open again! And I will be hiring! #JobPostComing www.training.nih.gov/research-tra...

submitted 58 days ago • 2 comments

Challenging times. Harvard at risk of losing $9 billion in federal funds as US launches review www.reuters.com/world/us/us-...

submitted 66 days ago • 0 comments

New this evening (3/28): Major update in NIH grant termination numbers. ❌ 695 NIH grants now terminated (up from 429) ❌ 232 on HIV/AIDS ❌ 44 on cancer ❌ 28 on Alzheimer's ❌ 123 on Covid* *And this doesn't count cancelled non-NIH Covid grants. HUGE THANKS to @noamross.net for pushing the updates!

submitted 69 days ago • 3 comments

“If large numbers of academics working in the U.S. do decide to leave, Gold doubts other countries will be able to absorb them all. The end result, he warns, could be an exodus of talent from global science. “My biggest fear,” he says, is that “we’re going to lose a cohort of researchers.”” 🧪

submitted 76 days ago • 16 comments

Some scientists in the United States have told Nature that they are considering leaving the country in the wake of widespread disruption to research brought in by the Trump administration Are you thinking about leaving? https://go.nature.com/4bMGd0J

submitted 82 days ago • 12 comments

A #SciencePerspective by @zalaly.bsky.social and @erictopol.bsky.social identifies key issues that need to be prioritized in the study of #LongCovid. Learn more on #LongCovidAwarenessDay: scim.ag/3XKbds3

submitted 82 days ago • 10 comments

Uncovering the road to MIS-C… -TGFβ links EBV to multisystem inflammatory syndrome in children- Brilliant work by a massively brilliant team. #LongCovid #MISC #KD www.nature.com/articles/s41...

submitted 85 days ago • 2 comments

This is really, really bad. Columbia made the mistake of thinking that placating the administration would spare them. Other universities made the mistake of thinking it would stop with Columbia. It won’t stop without disciplined pushback; it’s an existential question for American universities.

submitted 85 days ago • 66 comments

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

submitted 90 days ago • 16 comments

If you like chromatin remodellers and centromeres, this might be of interest. In it, we generated omics data from isogenic PBRM1 cell lines, which we hope is of use to the community, freely available (when evil forces aren't messing with the publicly funded websites 🙄) www.nature.com/articles/s41...

submitted 92 days ago • 2 comments

Wow Just Wow youtu.be/G8ECt04qPos?...

submitted 94 days ago • 5 comments

Heartbreaking chats this week with students thinking of giving up on their dreams of getting a PhD. They worry about getting in PhD programs and careers post PhD. My suggestions: don’t be hasty, think broadly incl EU & Canada, & careers beyond traditional academia. What’re you telling your students?

submitted 97 days ago • 20 comments

Many US students don’t know how to seek opportunities outside the US. With some help from our colleagues in EU and Canada, we could put together a consolidated website of PhD opportunities and scholarships outside the US, organized by field. There might still be time for this year in some places.

submitted 97 days ago • 58 comments

Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis | Science Immunology www.science.org/doi/abs/10.1...

submitted 101 days ago • 0 comments

Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...

submitted 101 days ago • 45 comments

The University of Pittsburgh confirmed Friday that there would be no new Ph.D. offers of admission while Pitt works to understand how reduced federal aid could impact the institution.

submitted 104 days ago • 56 comments

Freeze meetings -> reviews stop Reviews stop -> no scores No scores -> no recommendations No recommendations -> no awards No awards -> no $ No $ -> job & career loss, projects halted, lost discovery/cures/innovation + more We have a narrow window before the science supply chain grinds to a halt.

submitted 106 days ago • 0 comments

www.nature.com/articles/d41...

submitted 117 days ago • 1 comment

The Howard Hughes Medical Institute, the nation’s largest private funder of biomedical research, yesterday killed a $60 million program aimed at making universities’ STEM education more inclusive. scim.ag/3EtS0US

submitted 119 days ago • 83 comments

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it. www.science.org/content/blog...

submitted 121 days ago • 21 comments

The gears of the grantmaking machinery at NIH have begun moving again, after a 2-week standstill following a controversial ban on communications imposed by President Donald Trump. scim.ag/4aLQ0U6

submitted 122 days ago • 2 comments

SOME GOOD NEWS ABOUT NIH FUNDING Closed sessions of institute and center Advisory Counsel meetings are now permitted. This is where grant applications are discussed and approved for potential funding. Open sessions where there are public presentations and discussions are still not allowed.

submitted 122 days ago • 11 comments

ASM did a spotlight article on me last February and it has also been taken down as “under review”. Other spotlight articles are still up so not sure how else to interpret this besides the obvious. It feels pretty crappy to have been singled out and I won’t be engaging with them in the future.

submitted 123 days ago • 23 comments

What it’s like being a PI right now…

submitted 125 days ago • 0 comments

Since 1991, the NIH Science Education Partnership Award (SEPA) is dedicated to K-12 students & funds innovative STEM educational projects. It supports our EvolvingSTEM program that engages >1500 students/yr in authentic research. 🚨Its Program Announcement (PAR-23-137) is now GONE.😡 nihsepa.org

submitted 126 days ago • 10 comments

A mechanism for maintaining and spreading H3K9me3 in heterochromatin from the Fejes Toth and Aravin labs that depends on the local H3K9me3 density: HP1 dimers recruit SetDB1 to chromatin by simultaneously binding H3K9me3 on histone H3 and auto-methylated SetDB1. www.biorxiv.org/content/10.1...

submitted 132 days ago • 0 comments

A thing I didn't know. You can see who you've blocked, who's blocked you (interesting!) and lists you're on on Bluesky if you go to clearsky.app (this time unlinked to me🙄)

submitted 149 days ago • 5 comments

Humans: “We should exercise our immune muscles by catching viruses.” Viruses:

submitted 159 days ago • 8 comments

www.harvardmagazine.com/2025/01/harv...

submitted 168 days ago • 0 comments

Excited to share the preprint of the last portion of my grad work with co-first-author Gemechu Mekonnen and my adviser Sua Myong! We show that the RNA helicase DDX6 can tune the nucleation and fluidity of FUS condensates, including ALS-linked variants. Read more here: papers.ssrn.com/sol3/papers....

submitted 170 days ago • 0 comments

Excited to share the first of 2 new papers diving into functions of UHRF1 ubiquitin ligase activity. Here, a connection to the support of 5mC maintenance in regions of low CpG density. These same regions are prone to 5mC loss in cancer. A potential mechanistic link to PMD formation. #epigenetics

submitted 186 days ago • 1 comment

H3-H4 histone dimers act as copper reductase. This is important because ETC and SOD1 require bio-usable Cu+ for function. This article shows a new mechanism by which chromatin histones can affect the cell metabolism via a new role in metal processing #redoxepigenetics www.science.org/doi/10.1126/...

submitted 186 days ago • 1 comment

The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation www.biorxiv.org/content/10.1...

submitted 192 days ago • 10 comments

Waiting for ASM Journals here

submitted 192 days ago • 0 comments

Learning the Language of Life with AI in 4K AlphaFold; New Life Science LLMs; Virtual Lab; Impact and Future;

submitted 193 days ago • 0 comments

Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web. 🌐 bfvd.foldseek.com 💾 bfvd.steineggerlab.workers.dev 📄 academic.oup.com/nar/advance-...

submitted 194 days ago • 6 comments

Hi Bluesky! I am Phd student who work with Epstein-Barr Virus latency maintenance and lytic reactivation.

submitted 201 days ago • 0 comments

I made a list of Herpes virologists you can sue to follow. Please let me know who is already here and I missed! : bsky.app/profile/did:...

submitted 195 days ago • 4 comments

This #glycotime work by @virusesimmunity.bsky.social is intriguing; terminal GlcNAc is a viral epitope recognized by Abs that keep endogenous retroviruses at bay. Must be something about the context of that GlcNAc, would love to see some followup structural biology. www.science.org/doi/10.1126/...

submitted 195 days ago • 1 comment

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation journals.plos.org/plospathogen...

submitted 195 days ago • 0 comments