gottschalklab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

This would be a great time for everyone to be cool when reviewing manuscripts and not request $25,000 worth of new experiments that don’t substantially advance or validate the study...

submitted 7 days ago • 4 comments

New powerful article up in the New York Times on cancelled and delayed grants www.nytimes.com/interactive/...

submitted 7 days ago • 11 comments

Super cool new paper from the O'Shea lab. STAT interactions and consequences for inflammatory responses during viral infection. www.science.org/doi/10.1126/...

submitted 7 days ago • 1 comment

@jclinical-invest.bsky.social preview: IL-13 priming in precursors drives beige adipogenesis and enhances metabolic homeostasis www.jci.org/articles/vie... article www.jci.org/articles/vie...

submitted 8 days ago • 0 comments

Cytokines 2025 promises to be an exceptional program! Visit seattle.cytokinesociety.org for the full list of invited speakers, to submit your abstract for an oral or poster presentation by June 18, or register today. You don't want to miss this year.

submitted 9 days ago • 1 comment

Check out this multiomics study by @naehasubramanian.bsky.social on Lyme disease patients. It reveals localized immune responses at the site of infection, rather than in the periphery. www.biorxiv.org/content/10.1...

submitted 11 days ago • 1 comment

Stat1 gain-of-function mice fail to resolve inflammation in viral infection because of insufficient early STAT4–IFN-γ responses @sciimmunology.bsky.social www.science.org/doi/10.1126/...

submitted 12 days ago • 1 comment

Heartbreaking effects of NSF, Americorps cuts to Pittsburgh’s after school programs that support and enrich our city’s kids. The need and benefits of these programs is obvious. Isn’t this what we pay taxes for? Doubt philanthropy can take over. www.publicsource.org/federal-fund...

submitted 14 days ago • 0 comments

submitted 19 days ago • 0 comments

David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏 youtu.be/8YhJM6zxYDw?...

submitted 19 days ago • 1 comment

"Modeling the #HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death" We're pretty excited about this one. doi.org/10.1182/bloo...

submitted 29 days ago • 0 comments

We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...

submitted 35 days ago • 3 comments

#WeekendRead! #EveryCellIsAnImmuneCell! Peng Bai Marichal &co show @ Science Immunology that endothelial cells produce TGFb to differentiate monocytes into #lung interstitial macrophages preventing aging & fibrosis www.science.org/doi/10.1126/...

submitted 45 days ago • 0 comments

#EpigeneticPower! Ivashkiv, Mishra &co show @natimmunol.bsky.social that anti-inflammatory IL-10 epigenetically silence IRF1 & IRF5 gene transcription by decreasing H3K27ac & chromatin accessibility, thus preventing sustained #interferons & IL6/TNF signaling! www.nature.com/articles/s41...

submitted 50 days ago • 1 comment

We have an opening for a PhD/Postdoc in Spatial Omics for Cardiology in Heidelberg 🫀 #job #academicjob #phd #postdoc #cadiology 👇 jobrxiv.org/job/heidelbe...

submitted 51 days ago • 0 comments

The five senses of immunity #immunology

submitted 54 days ago • 0 comments

Hearing from sources that grant terminations are starting now, likely targeting grants aimed at broadening participation of underrepresented groups in science.... which congress explicitly asks NSF grants to do.

submitted 54 days ago • 3 comments

🚨 Not a drill: NSF GRFP results are NOW OUT!!!!! But...good news and bad news. 👍 I'm thrilled for the grad students for whom getting this award will be life-changing, esp now. 👎 # of fellowships went down by 51% (1000 this year vs. 2036 last year) See here: www.research.gov/grfp/Awardee...

submitted 65 days ago • 14 comments

Congrats to @sarahmbelcher.bsky.social & @gottschalklab.bsky.social, alums of the Supporting Our Scientists Program, for being selected for the 2025 Senior Vice Chancellor’s Lecture Series! #PittResearch #WomenInScience 👏 Dr. Belcher presented Feb. 21 👏 Dr. Gottschalk presented March 14

submitted 70 days ago • 0 comments

🚀 Apply now 🚀 The new Max Planck #Postdoc Program offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. postdocprogram.mpg.de #ScienceCareer #PostdocProgram

submitted 72 days ago • 1 comment

Happy to share our reflections @cp-trendsimmuno.bsky.social on our favourite cells: IL-1β+ macrophages 🔥🔥🔥 Molecular, spatial, temporal, functional properties in cancer and beyond... it's all in there from the awesome Nicoletta Caronni, Federica La Terza and @frosio.bsky.social tiny.cc/y94f001

submitted 71 days ago • 0 comments

Co-Chairs, Michael Gale, Jr. and @ramlabuw.bsky.social invite abstract submissions for Cytokines2025. Topics include adaptive immunity, cytokine signaling, interferon stimulated genes, structure- function, and more. Submit: seattle.cytokinesociety.org/call-for-abs... Deadline is May 18, 2025.

submitted 77 days ago • 0 comments

Labeling your axes and then explaining them slowly is perhaps the biggest bang for the buck you can get for making your slides more understandable.

submitted 91 days ago • 5 comments

So happy to share our latest paper on #AlveolarMacrophage responses to low-dose #LPS led by @pamelialim.bsky.social!AM #innate responses are enhanced by IFN-beta due to low c-Maf and IL-10 expression, with implications for AM responses to respiratory infections and environmental exposure. #ImmunoSky

submitted 99 days ago • 3 comments

15 new Postdoctoral Fellow jobs in Immunology! Job titles and links below👇 #Sciencejobs #AcademicSky 1/16

submitted 99 days ago • 1 comment

Sanofi is hiring! 4 new positions available @sanofi Individual job details below!👇 #ScienceJobs 1/5

submitted 101 days ago • 1 comment

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

submitted 102 days ago • 63 comments

Yinz ready to stand up for science?

submitted 106 days ago • 3 comments

🚨PA colleagues: "Senator Fetterman wants to hear from you about how the federal funding freeze is affecting Pennsylvania." "If your project has been impacted, please fill out our constituent impact form:" forms.office.com/g/mFv2JAPxpC Get out your Other Support and share that info!

submitted 109 days ago • 5 comments

New study in @cellpress.bsky.social by Allen Distinguished Investigator @elowitzlab.bsky.social and collaborators explores the versatility of protein dimers. #FrontierScience 🔗 www.cell.com/cell/fulltex...

submitted 112 days ago • 0 comments

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️

submitted 113 days ago • 1 comment

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

submitted 123 days ago • 82 comments

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic. globalnews.ca/news/9793403...

submitted 122 days ago • 526 comments

www.fiercebiotech.com/research/rep...

submitted 123 days ago • 2 comments

I am starting this morning by reaching outside of my science echo chamber (posting on facebook) to explain why the NIH matters and why the new indirect rate policy will be catastrophic to everyone

submitted 123 days ago • 4 comments

Here's the script I wrote for calling my representative about the latest horrors. Would probably benefit from a better breakdown of how indirects work, but I didn't want it to get too long. Now I just need to decide whether to call now or wait for Monday when I can talk to an actual person.

submitted 124 days ago • 5 comments

www.senate.gov/senators/sen...

submitted 124 days ago • 0 comments

www.house.gov/representati...

submitted 124 days ago • 0 comments

A new issue of Cell is out, featuring the 4 winners of the Rising Black Scientists Awards. Their essays bring hope, inspiration and reinforce the importance of equity in science. Do take a moment to check them out: www.cell.com/cell/current @cp-cell.bsky.social

submitted 125 days ago • 5 comments

Absolutely delighted that Ron Germain has been recognised with the 2025 AAAI Mentoring Award! Very lucky to have been (and still be) his mentee!

submitted 132 days ago • 1 comment

Why scratching makes a rash worse and a potential benefit to scratching--it reduced S. aureus on skin. Andrew Liu's paper from our lab is out now at #science #neuroimmune #immunology www.science.org/doi/10.1126/...

submitted 132 days ago • 8 comments

Caroline Larkin is paving her own path after graduation and integrating science into the things she loves. “I think science needs a voice to be heard in government and business decisions, so I’m excited to communicate that to people,” she said. tinyurl.com/CarolineLarkin

submitted 133 days ago • 0 comments

Not a day for levity, but I needed something to distract myself

submitted 134 days ago • 5 comments

I'm delighted to share a new story from our lab published today at @cp-cellmetabolism.bsky.social! In it, we describe how cellular therapies for cancer can be metabolically and epigenetically enhanced by redirecting how glucose is utilized during in vitro expansion. 1/ www.cell.com/cell-metabol...

submitted 134 days ago • 2 comments

New: Lee et al. @harvardmed.bsky.social provide a compendium of early transcriptional responses to major inflammatory #cytokines across all major immunocyte lineages of the mouse, highlighting unappreciated relationships btwn these cytokines and with other cytokine families https://buff.ly/4gn71Fg

submitted 134 days ago • 0 comments

Who will develop the technologies of the future? The answer is simple...look to the past. Institutions that invest in exploration make discoveries that change the world. Those that do not, do not.

submitted 135 days ago • 1 comment

Innate immune memory is stimulus specific @arjunraj.bsky.social @aofarrell.bsky.social doi.org/10.1101/2025...

submitted 136 days ago • 1 comment

Tools "Here, we present parallel-flow projection and transfer learning across omics data (PLATO), an integrated framework combining microfluidics with deep learning to enable high-resolution mapping of thousands of proteins in whole tissue sections." www.cell.com/cell/fulltex...

submitted 136 days ago • 0 comments