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grantkinsler.bsky.social
Postdoc at UPenn thinking about mutations, cells, and evolution.
34 posts 387 followers 748 following
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Check out this brand new fellowship from the Simon’s Foundation in Ecology and Evolution. Incoming grad students this year are eligible to apply. No citizenship restrictions. www.simonsfoundation.org/grant/simons...

submitted 4 days ago • 0 comments

1/n 🧵 Excited to share our new paper! We developed a framework to reveal hidden simplicity in how organisms adapt to different environments, particularly focusing on antibiotic resistance evolution. #EvolutionaryBiology #MachineLearning

submitted 22 days ago • 1 comment

Very excited about this work by @mrazo.bsky.social in collaboration with www.madhavmani.com bsky.app/profile/mraz... I am so lucky to be able to collaborate with such brilliant people! Learned a lot. This is our first foray into ML approaches and I am quite taken with their power 1/n

submitted 22 days ago • 1 comment

Why is sex so common if it's so costly? Super excited to share our new preprint “Sex decreases the pleiotropic costs of local adaptation”, where we bring a new angle to this age-old evolutionary question. Co-led by Parris Humphrey, in Michael Desai's lab. Short thread here: (1/n)

submitted 64 days ago • 4 comments

"The end of the genetic paradigm of cancer" - a provocative piece in @plosbiology.org from Sui Huang, Ana Soto & Carlos Sonnenschein: "We expect that the diminishing returns from the ceaselessly growing databases of somatic mutations... may soon reach a pivot point" journals.plos.org/plosbiology/...

submitted 80 days ago • 0 comments

Super excited to be launching NimbusImage.com! Cloud-based image analysis to democratize machine learning! Documentation here! docs.nimbusimage.com

submitted 81 days ago • 7 comments

1/ Hey y'all, I'm excited to share my latest paper, which is out now in PNAS! We introduce FAVA, a statistical framework to measure compositional variability across microbiome samples. If you want to measure variability across a stacked bar plot, FAVA is for you! Paper: doi.org/10.1073/pnas...

submitted 83 days ago • 5 comments

Excited to be co-chairing the Molecular Mechanisms in Evolution GRS this year! Please submit an abstract by this Sunday (3/16) if you want to be considered for a talk!

submitted 84 days ago • 0 comments

I’m thrilled to share my first ever publication, now published in PNAS! www.pnas.org/doi/10.1073/... With mentorship from the amazing @ksxue.bsky.social, I looked at how the outcomes of species introductions to microbial communities are influenced by the number of introduced microbes.

submitted 87 days ago • 1 comment

Delighted to share a major update on our work investigating age-related deceleration in clonal haematopoiesis. Takehome: Widespread and substantial deceleration in fitness with age! Amazing effort by PhD student Hamish MacGregor 💪 www.biorxiv.org/content/10.1...

submitted 91 days ago • 1 comment

I'm so happy that I can finally share the results of my first postdoc paper with @baym.lol!!! Turns out plasmids are an amazing system to study multi-scale evolution and we can track within-cell and between-cell dynamics! (1/n) www.biorxiv.org/content/earl...

submitted 104 days ago • 10 comments

1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social. www.nature.com/articles/s41...

submitted 92 days ago • 16 comments

First of a few publications on lions for this year and one which relied heavily on federally funded collections and federal-academic partnership. The folks who know these collections and populations intimately were instrumental in this work and we are delighted to share it. Feedback welcome.

submitted 95 days ago • 0 comments

Happy 37th birthday to the LTEE! the-ltee.org/history/

submitted 102 days ago • 8 comments

Excited to share SpaceBar - our new method for labeling and detecting clones with imaging-based spatial transcriptomics platforms! w/ Yael Heyman and @arjunraj.bsky.social www.biorxiv.org/content/10.1... 🧵

submitted 108 days ago • 2 comments

Very excited to have this paper officially out. This one is pretty special... Unfortunately, @kevinwoodum.bsky.social passed away when this paper was in its final stages. He was my biggest supporter, and I miss him deeply as a mentor and friend.

submitted 148 days ago • 2 comments

It is that time of the year again when @odedrechavi.bsky.social and I do our annual “your favorite paper of the year” thread. Now only on Bluesky! Please link to your favorite paper in the comments and say a few words why you loved it so much. Happy holidays and happy reading!

submitted 162 days ago • 17 comments

Is it “winner-takes all” when the simplest living things compete? Check out my fresh publication on phage coexistence in Science and a thread below🧵 www.science.org/doi/10.1126/...

submitted 175 days ago • 5 comments

A really lovely perspective on our paper led by @grantkinsler.bsky.social and Yuping Li in Plos Biology! journals.plos.org/plosbiology/...

submitted 178 days ago • 0 comments

In a cool twist on their previous work, @grantkinsler.bsky.social Yuping Li @gsherloc.bsky.social & @petrovadmitri.bsky.social use yeast to reveal that #evolution involves a) early large-effect pleiotropic mutations, b) a shift towards more modular adaptation @plosbiology.bsky.social plos.io/4glXoXJ

submitted 182 days ago • 0 comments