hypothesisfund.bsky.social
Nimble funding for nimble minds.
www.hypothesisfund.org
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5/ #DYK that microbes from the deep ocean 🌊 can make their own food without the sun? Awardee Elaine Luo (@oceanmicrobes.bsky.social) will study how these organisms carry out that process, and how they shape our global carbon cycle 🌍.
🥳 Congrats Dr. Luo!
🙏 #HFScout Angel White
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4/ Can a cell's skeleton carry instructions that guide when cells should stick together vs move💨? Awardee @rogerslabucd.bsky.social aims to decode how cells transform in a process critical for development & cancer.
🥂Congrats Dr. Rogers! @ucdavisvetmed.bsky.social
🙏 #HFScout @drkhaynes.bsky.social
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3/ How do respiratory viruses penetrate the layer of protein meshwork that protects our airways🫁? Awardee Michael Vahey uses a novel approach to study viral entry of these cellular structures w/ unprecedented detail!
🎉 Congrats Dr. Vahey!
🙏 #HFScout Jeanne Stachowiak
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2/ How do viruses spread w/o bursting💥 & killing host cells? Awardee @drstarbird.bsky.social aims to discover the mechanisms of an understudied driver of viral spread-which could change the future of virology research!
🍾Congrats Dr. Starbird! @unc-bcbp.bsky.social
🙏 #HFScout @harmitmalik.bsky.social
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The first episode drops on Monday, May 12th! Find it on the @scifri.bsky.social podcast: www.sciencefriday.com/the-leap/. 4/4
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Hosted by gifted storyteller, @flichtman.bsky.social, The Leap dives deep into the personal stories behind some of the #boldestscience. What drives scientists to pursue their boldest ideas, to bet on themselves, to put their careers & safety on the line in the search for truth? 3/
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At the Hypothesis Fund, we support scientists to take intellectual risks & go after their biggest ideas🌠. We celebrate the courage required to make groundbreaking discoveries, & believe that science is not just a discipline, but a **daring & profoundly human** endeavor. 2/
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4/ Awardee Tim Cernak is decoding the chemical mechanisms behind toxin production in an endangered 🐸 species. His project may uncover gene-environment interactions that are critical to restoring natural defense mechanisms.
🎉 Congrats Dr. Cernak! @umich.edu
🙏 #HFScout Janet Jansson
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3/ Leveraging large population studies & small scale lab experiments, Awardee @hjp.bsky.social will integrate diverse datasets to strengthen our ability to interpret rare genetic🧬 variants in disease. 🤯
🥳 Congrats Dr. Pimentel!
🙏 #HFScout Kay Tye
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2/ Awardee Danielle Guez Barber will examine how blood & brain macrophages impact the severity of hypoxic-ischemic brain🧠 injury. Her work may be key to addressing the 2nd leading cause of neonatal death & disability.
🍾 Congrats Dr. Guez Barber! @cudeptofmedicine.bsky.social
🙏 #HFScout Kay Tye
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4/ With a 'molecular scalpel'🔪 to 'biopsy' membrane sites where cells/organoids make contact, Awardee @moitrayee-lab.bsky.social's research may reveal new insights into cellular processes & disease development (e.g. ALS).
🎉Congrats Dr. Bhattacharyya! @yale.edu
🙏#HFScout @krishnanyamuna.bsky.social
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3/ Awardee @cmholab.bsky.social tackles the complex challenges of protein sequencing by leveraging microbial molecular machinery. Her work can revolutionize how we study protein function/structure & our understanding of biology🤯.
🥳Congrats Dr. Ho! @columbiauniversity.bsky.social
🙏#HFScout Ellen Yeh
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2/ By introducing new 'building blocks' to protein synthesis, Awardee Ahmed Badran aims to discover new functions in a key enzyme in photosynthesis, RuBisCO. His work may be key to combatting 💪#climatechange 🌎.
🍾Congrats Dr. Badran! @scripps.edu
🙏#HFScout @krishnanyamuna.bsky.social
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His multidisciplinary science thrives on collaboration: "I find great joy in talking w/ other scientists. The drive to better understand how the world works can lead to conversations & collaborations in new & unexpected directions, & I am always up for the adventure!"🌄4/4
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His research also involves the development of new measurement technologies, such as a tool that combines mobile devices with microscopy🔬 to enable rapid, low-cost diagnosis of neglected tropical diseases in remote areas. cellscope.berkeley.edu 3/
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His group is tackling fundamental science questions, such as: how does a "very small but very potent" fusogenic protein from a reovirus drive cell-cell membrane fusion? This mechanism is important for understanding how some viruses replicate and spread. 2/
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His multidisciplinary science thrives on collaboration: "I find great joy in talking w/ other scientists. The drive to better understand how the world works can lead to conversations & collaborations in new & unexpected directions, & I am always up for the adventure!"🌄4/4
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His research also involves the development of new measurement technologies, such as a tool that combines mobile devices with microscopy🔬 to enable rapid, low-cost diagnosis of neglected tropical diseases in remote areas. cellscope.berkeley.edu 3/
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His group is tackling fundamental science questions, such as: how does a "very small but very potent" fusogenic protein from a reovirus drive cell-cell membrane fusion? This mechanism is important for understanding how some viruses replicate and spread. 2/
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“I think I was too naive back then to realize that pursuing a hypothesis that upended established dogma was a career risk. I hope that as we grow more experienced in our careers, we will still have the courage to propose ideas that might meet with opposition.” 💯 4/4
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As a new faculty member, Jeanne made a paradigm-shifting discovery showing that proteins can drive membrane bending through a steric crowding mechanism. “The first few times we presented our data on this mechanism, it was seen as sacrilege!”😲 3/