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iainwilsonwien.bsky.social
Associate Professor interested in molecular glycobiology, glycomics of lower eukaryotes, glycan arrays, chemical glycobiology, classical music. Viva la libertà!
103 posts 249 followers 13 following
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I guess we need more unusual glycan standards, e.g., with GlcA or PC, to increase coverage of, e.g., insect structures! The 83% for MMF seems high for Sf9-produced Spike, unless the BEI stuff is very different from Novavax.
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I know that some people are not convinced. Without going through the data in detail or having peptides without other possible sites … it’s anyway a low overall claimed percentage.
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Question: can O-GlcNAc sites can be specified by HCD due to the lability of O-GlcNAc? One opinion expressed: 50% of O-GlcNAc sites in repositories are incorrect.
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We could be interested for non-mammalian samples.
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Thanks to Elisa & Callum for the modelling! I’m sure we can send more crazy structures for consideration!
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How was the GRC hotel‘s food? As Barga is in Italy, my culinary expectations at our GRC were far from fulfilled!
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EDD reminds me of the motif in GlcNAcTI (see Rini‘s paper from 2000).
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My personal experience: The standard of English in China and Japan is rather variable amongst young scientists, so a Chinese translation is certainly valuable. My own Chinese graduate student (10 years or more ago) had good conversational skills, but scientific English was not always understood.
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I agree. No insider deals!