mariaperica.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

A study in Nature Neuroscience shows that high alcohol concentrations during binge drinking activate a small GABAergic neuronal ensemble in the medial orbitofrontal cortex, which subsequently reduces further alcohol consumption. 🔒

submitted 13 hours ago • 1 comment

Rethinking excitation/inhibition balance in the human brain — a Comment article by Roi Cohen Kadosh #neuroscience #neuroskyence www.nature.com/articles/s41...

submitted 19 hours ago • 0 comments

MUSC Youth Collaborative ✨superstars ✨ Drs Anna Kirkland, Lindsay Squeglia and Lindsay Meredith busting some myths at the Just Say Know workshop at #RSA_ISBRA2025

submitted 1 day ago • 1 comment

First full day of @rsaofficial.bsky.social 2025 meeting. Great seeing friends/colleagues last night. Starts with a NIAAA update from Dr. Koob. Most notable take-aways: no more NIAAA study sections... 25% reduction in staff.... no news on budget... 1/2

submitted 1 day ago • 2 comments

Brain food: New Orleans edition #RSA_ISBRA2025

submitted 2 days ago • 0 comments

On the one hand, I got a paper rejected today. But on the other hand, I won an award today. Just another day on the ~emotional rollercoaster of academia~

submitted 4 days ago • 0 comments

A discrete GABAergic neuronal ensemble in the mouse medial orbitofrontal cortex (mOFC) that is selectively recruited in response to binge alcohol drinking and limits further drinking behavior www.nature.com/articles/s41...

submitted 7 days ago • 0 comments

An NIH staffer reacts to today's ruling: "I'm looking forward to the day that we are so slammed with work trying to reinstate everything that we had to terminate illegally — I'll work 24/7 to make that happen if I can."

submitted 7 days ago • 9 comments

What? Some good news on a Friday? Parent Fellowship Notices of Funding Opportunities are up! F30, F31, F32, F33 grants.nih.gov/grants/guide...

submitted 10 days ago • 4 comments

Happy 18th birthday ggplot2! #rstats

submitted 13 days ago • 16 comments

Bethesda Declaration is live! 300+ workers at NIH call out NIH and HHS leadership to stop weaponizing research and censoring scientists. Read and then consider signing letter of solidarity. @standupforscience.bsky.social www.standupforscience.net/bethesda-dec...

submitted 14 days ago • 0 comments

If you only test your associations in clinical samples you preclude any inferences about how a risk factor actually increases risk

submitted 22 days ago • 2 comments

🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence? We asked this in our new paper just out in #ScienceAdvances ✨ “Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling” 📄 www.science.org/doi/full/10.... 🧵⤵️

submitted 19 days ago • 3 comments

Want your NIH and NSF program officers and division directors to be fired and turned into political appointees? Deadline extended: 3 days left! Already 33,000+ public comments Comments can tank a proposed rule in court. 📣 Oppose the rule with a brief comment: shorturl.at/WKuBj

submitted 19 days ago • 3 comments

1/6 Why does the brain maintain such precise excitatory-inhibitory balance? Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning. www.biorxiv.org/content/10.1... led by @jrbch.bsky.social

submitted 28 days ago • 4 comments

This proposed budget is a policy statement, not an appropriation. There are still a lot of steps and potential changes ahead before it becomes one. This is not a time to sit quietly, team. Let's go.

submitted 23 days ago • 2 comments

Delighted to see this piece with Victor Ambros, @carlbergstrom.com, Carol Greider, @michaelemann.bsky.social, and @briannosek.bsky.social in the wild. Trump’s new ‘gold standard’ rule will destroy American science as we know it @standupforscience.bsky.social www.theguardian.com/commentisfre...

submitted 25 days ago • 4 comments

If you are in Atlanta or can get there and have the interest, this is a great opportunity to demonstrate clearly the insanity of these recommendations.

submitted 25 days ago • 2 comments

When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...

submitted 26 days ago • 1 comment

Excellent review by @talliezee.bsky.social and Matthew T. Birnie on the neurobiological mechanisms underlying the consequences of early life adversity. Highly recommended! www.cell.com/neuron/fullt...

submitted 32 days ago • 1 comment

My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!

submitted 32 days ago • 11 comments

🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees Already 14,000+ public comments, deadline is Friday 📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful Speak up! shorturl.at/WKuBj

submitted 33 days ago • 27 comments

Hot off the press! We found that electroconvulsive therapy (ECT) induces a previously undescribed, second brain event after seizure, called cortical spreading depolarization (CSD), using optical neuroimaging in both a mouse model to human patients. 🧵 below! doi.org/10.1038/s414...

submitted 36 days ago • 3 comments

A new #Neurosalience episode is out! 🧠 Advancing fMRI: Big data, reliability, deep phenotyping with Michael Milham and Peter Bandettini @milhammichael.bsky.social @fmri-today.bsky.social www.youtube.com/watch?v=NoOL...

submitted 37 days ago • 0 comments

Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n

submitted 52 days ago • 57 comments

This is a really neat AI app to help you plan/brainstorm research!

submitted 38 days ago • 1 comment

Better Code, Better Science - Introducing a new open-source book project on scientific coding using AI tools russpoldrack.substack.com/p/better-cod...

submitted 40 days ago • 2 comments

Out now, led by @alexanderhatoum.bsky.social! GWAS associations are enriched for existing psychiatric drug targets www.nature.com/articles/s43...

submitted 38 days ago • 0 comments

This. This is why we invest in biomedical research and development in this country. A bespoke gene-editing treatment for a baby born with a life-threatening disorder : Shots - Health News www.npr.org/sections/sho...

submitted 39 days ago • 2 comments

FYI -- virtual registration is "$0/students or academics, or if you can’t afford the paid options above"!

submitted 39 days ago • 0 comments

Neuronal activity influences the growth of #myelin sheaths along axons by signalling through metabotropic glutamate receptor 5 (mGluR5) on oligodendrocytes 🧪🧠 www.nature.com/articles/s41...

submitted 40 days ago • 0 comments

In a little over a week, Patrick Curran and Dan Bauer will livestream their FREE structural equation modeling workshop - May 19, 21, 23. Learn about covariance structure, path tracing, model fit, and the key statistical concept of Whack-A-Mole. #academicsky #StatsEd #stats centerstat.org

submitted 46 days ago • 0 comments

We have updated our database of funding opportunities for Early-Career Researchers (private foundations, federal, international) We have 456 entries, for which we provide $ amount, deadline, eligibility criteria, etc. Download this massive database here for free: research.jhu.edu/rdt/funding-...

submitted 47 days ago • 3 comments

New preprint on ND and co-occurring mental health problems from my lab, led by Chiara Caserini! Using longitudinal data from ABCD we asked: What drives poor mental health outcomes in children with high ND traits? Here's brief summary 🧠🌳🏡 www.medrxiv.org/content/10.1.... 1/n

submitted 52 days ago • 1 comment

🚨 Just out in Nature Medicine: the RESiLIENT study (n=3,936; 9 CBT-based arms vs 3 controls) 📱 Massive RCT of smartphone-delivered CBT skills It challenges major assumptions in psychotherapy research. 📄 www.nature.com/articles/s41... 🧵Three key insights:

submitted 55 days ago • 4 comments

Taking the day off of being a clinical psychology intern to listen to Nora Volkow, George Koob, Eric Nestler, Marina Wolf and so many other brilliant scientists celebrate the career of Peter Kalivas and his research contributions. Low key toooootally starstruck rn 🤩

submitted 54 days ago • 0 comments

🗣️AMPLIFY AMPLIFY AMPLIFY!!! Please comment!

submitted 61 days ago • 0 comments

‼️ New paper @ Child Development discussing why it is inappropriate to use traditional common factor models to model adverse childhood experienced (ACEs) and other stressor inventories ‼️ Read full (brief) paper at srcd.onlinelibrary.wiley.com/doi/full/10.... @srcdorg.bsky.social #PsychSciSky 1/9

submitted 62 days ago • 10 comments

Ever wonder how many lives have been saved by NIH-funded research - including your own? Enter any medical condition and instantly see how your tax dollars transformed science into survival. www.ourhealthroi.com

submitted 64 days ago • 26 comments

Psychiatric disorders share genetic roots, but the mechanisms are unclear. With exon-level brain data, we linked common & rare variants to 110 core genes in pathways such as cortisol & dopamine cascades, mainly in excitatory neurons, offering new therapeutic targets 🧠✨ www.nature.com/articles/s41...

submitted 64 days ago • 0 comments

there are people out there who really, truly can't wait to just "hop on a quick call". like, genuinely for the love of the game. and they have to be stopped.

submitted 66 days ago • 50 comments

Thoughtful paper showing that true within-person effects don't always translate to between-person differences and discussion of why that might be. By Neubauer, Koval, Zyphur, & Hamaker #PsychSciSky #AcademicSky psycnet.apa.org/doiLanding?d...

submitted 67 days ago • 3 comments

New article out at Human Brain Mapping showing that brain age ≠ brain ageing (estimating brain age on all available features). This is not the only article showcasing this. Brain age is still useful, but be careful about the longitudinal claims. doi.org/10.1002/hbm....

submitted 69 days ago • 1 comment