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michaelhoffman.bsky.social
Chair, Computational BIology and Medicine Program, Princess Margaret Cancer Centre, University Health Network. Associate Professor, Medical Biophysics, University of Toronto. Disclosures: https://github.com/michaelmhoffman/disclosure/
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You “gave up everything?” does that mean you were kidnapped by masked goons and sent to an offshore slave camp without due process, or

The flood of encomiums and morality tales about Elon's turn in Washington cldn't be more predictable, vapid & sickening. If you want a story, get me the story about the crisis comms team directing this. He ran anti-constitutional blitzkrieg thru the federal government, did massive harm, violated ...

Congestion pricing in NYC has been a policy miracle. It has dramatically reduced air and noise pollution, saved drivers time money and New Yorker *lives.* There has been a ~50% reduction in injury crashes in the congestion relief zone. Pricing driving delivers better transportation for *everyone.*

Once again, it's not "doxxing" to report the name of a government employee.

BREAKING: Federal court says Trump exceeded his authority to impose tariffs under IEEPA. storage.courtlistener.com/recap/gov.us...

No one ever talks about how the Titanic successfully crossed 80% of the Atlantic

Hindenburg Has Partially Successful Trip To US.

I no longer have the right to free speech and I have to show my papers to heavily armed ICE officers every time I cross the street. But I can still own an AR-15 and that is what freedom really means.

The war on science in the US is already having an effect on private sector research like AlphaFold. Bears repeating but the private sector builds on top of things created by academic research for the public good. This hurts everyone.

the climb was arduous but finally we reached the temple. the guru sat motionless as night descended. hours passed before he finally spoke and he said only this: "the backlash against shitty behavior is what causes shitty behavior, actually." it was then i knew i'd found the joe rogan of the left.

Me (crying): Please...I just need to message my coworkers Microsoft Teams Developers: No you don't. You want a Bunch of Bullshit that also changes week-to-week for some reason

We're having a "scientific conferences need to become more accessible" conversation again, this time in terms of the Trump administration making it unsafe for some international colleagues to join us in the US. I'm on the Board of multiple orgs that plan conferences. Here are some thoughts. 🧵🧪🦑🌎

“A sane country does not wage war against civilians, does not kill babies as a pastime, & does not engage in mass population displacement...The Jewish people, who have endured persecution, pogroms, & genocides throughout our history...are the ones now taking actions that are utterly unconscionable.”

Criticism of Israeli war crimes isn't anti-semitism. This essay on Israel's war crimes was penned by, let me see, oh, Israel's former Prime Minister. www.haaretz.com/opinion/2025...

Academia in 2025: For weeks I’ve been working through botched copy-edits of my monograph, outsourced by the publisher to a company I’d never heard of, until it finally dawned on me the terrible job might be AI. A quick search confirmed the company recently launched new AI software, which now means..

The bad news is Bluesky's daily unique liker count is down over a three-month period. The good news is you can just use whatever websites you want to without caring about that kind of stuff for any reason

We should have a memorial day for COVID. It is horrific that we as a society have done virtually nothing to remember the millions who have died. Rushing to forget what happened also makes it much more likely that we will continue to repeat our deadly mistakes.

How is it that Reading Rainbow, produced by Buffalo Toronto Public Media, is not available on any streaming services in Toronto?

“Instagram has no idea what my styleis, every clothing ad is something I’d never wea…. holy shit…”

"Getting permission from Chanel would kill the fake handbag industry"

Billionaires spend a decade funding anyone and everyone who says science is broken, leverage it to wrest control of science, and it’s somehow uncouth to point that out.