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microbegrrl.bsky.social
Microbiome, drugs, phages, ecology, AI, the Bronx
38 posts 3,163 followers 1,814 following
Prolific Poster

Sharing the most significant work from my group, led by the @evolvingstem.bsky.social team. Come for the discoveries of how Pseudomonas adapts in biofilms, stay for the story of how they were discovered by thousands of young scientists in grades 9-12. 🧪🧫🧬🧵 www.biorxiv.org/content/10.1...

Simon Fraser University invites applications from world-renowned researchers for the Canada Excellence Research Chairs (CERC) 2026 competition, offering up to $8M over eight years to support innovative and impactful research. Learn more and apply by June 30: www.sfu.ca/vpacademic/a...

check out our newest paper in JB: Kuchma, Geiger et al. identify key components of flagellar-mediated surface sensing system of P. aeruginosa. journals.asm.org/doi/10.1128/... @asm.org #Jbacteriology

Various classes of riboswitches bind the nitrogen-rich compound guanidine, but its physiological significance remains elusive. In #JBacteriology, discover what we know so far about this important compound and open questions to guide future research: asm.social/2rW

Now open - LOIs for the Investigators in the Pathogenesis of Infectious Disease (PATH) program. Deadline is July 17 @ 3pm ET. More information here: buff.ly/iSu3v60 #bwfpath #GrantOpportunity

📣 Happy to share our review on host-microbiome genomics! We synthesize the growing field exploring interactions between human genetics and the microbiome, building a roadmap for mapping the dialogue between our genes and microbes Out now in Nature Reviews Genetics👇 www.nature.com/articles/s41...

Super happy to share our latest in @natcancer.nature.com co-led by @pannunziolab.bsky.social! We review the complex role of the circadian clock in genome integrity, DNA repair, immunity, metabolism, and cancer with a specific focus on early-onset cancer. Check it out! www.nature.com/articles/s43...

Ecological assemblages may be spatially organized by both context dependency and general processes. Here the authors find general patterns in the organization of regional biodiversity in biogeographical regions www.nature.com/articles/s41...

A single-cell perspective on host–virus dynamics in the ocean @cp-trendsmicrobiol.bsky.social Opinion from @vardilab.bsky.social www.cell.com/trends/micro...

After working at it for a while, I finally convinced @clequere.bsky.social to join Bluesky. Many of you know her, but if not, she’s an extraordinary scientist whose impact on climate science and society is hard to measure. Please give her a follow. research-portal.uea.ac.uk/en/persons/c...

We’re hiring: GIMM is launching its first call for Group Leaders. Looking for scientists ready to push boundaries, ask bold questions & build the future of biomedical discovery. 🔗 gimm.pt/jobs/open-ca... 📅 Apply by June 8 #ScienceJobs #GroupLeader #BiomedicalResearch

E. coli prophages’ arsenal against temperate phages New work isolates temperate phages from diverse E. coli strains, enabling identification of 17 conserved, prophage-encoded anti-phage defense systems that protect against other temperate phages www.cell.com/cell-host-mi...

📣 Latest from the lab: Performance of deep-learning-based approaches to improve polygenic scores www.nature.com/articles/s41... Its thought deep learning will substantially improve PGS but the reality is MANY have tried but no/little gain has been seen so far. Here we report our negative results.

He's right. "Nothing short of devastating" By @holdenthorp.bsky.social @science.org www.science.org/doi/10.1126/...

Not all persister bacteria are dormant! 🦠 Single-cell imaging of over a million #EColi shows that many antibiotic-resistant persisters were actively growing before drug exposure. Persistence appears to be more dynamic than once thought. buff.ly/04T4L1k

Introns have to come from somewhere, right? @celineh2ooo.bsky.social and I looked at multiple genome alignments with 1000s of genomes and found 342 cases where humans (and our relatives) had gained a new intron. Still not sure where these come from, but it's a fascinating question

📢 Big day for archaeal microbiology! Today, we jointly shed light on the mysterious world of archaeal extracellular vesicles from human gut archaea - published in @natcomms.nature.com ‬ in parallel with our precious colleagues around @mkrupovic.bsky.social 🇦🇹🤝🇫🇷.

We have a new 3-year postdoc position in our group at the @hifmb.de to study plasmids and plasmids systems of the marine environment to survey their utility in microbial responses to environmental change. Please see the official job ad here, and spread the word: jobs.awi.de/Vacancies/20...

A versatile information retrieval framework to quantify sample activity and similarity in large-scale profiling data @natcomms.nature.com @alxndrkalinin.bsky.social @shantanu-singh.cc @drannecarpenter.bsky.social www.nature.com/articles/s41...

How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.

Joint w/@asinclair.bsky.social and the #SCIMaP team: brief correspondence in @nathumbehav.nature.com on the impact of NIH indirect cost cuts on the economy and employment, impacts that will only worsen given similar proposals for NSF/DOE + overall science proposal. rdcu.be/eo3Hp

"Imagine the auto industry without 3D printing. NSF funded that. Artificial intelligence? NSF. MRI machines that help doctors diagnose you? NSF. Doppler radar technology that makes aviation safer by conquering wind shear? NSF. Duolingo‘s underlying programming? NSF. The internet itself? NSF."

High-affinity PQQ import is widespread in Gram-negative bacteria www.science.org/doi/full/10.... #jcampubs

1 plant hormone receptor ☘️ 3,500 mutants, to single-site saturation 🧬 >45,000 binding and abundance measurements 📶 Very happy to present our latest work – where deep mutational scanning meets the world of small molecules.

 www.biorxiv.org/content/10.1...

 With @benlehner.bsky.social [1/7]

Out now in @nathumbehav.nature.com: Cuts to NIH funding will impact the economy and employment nationwide. We visualize these losses and advocate for a theory-driven approach to communicating local, self-relevant impact. w/ @joshuasweitz.bsky.social + SCIMaP team: www.nature.com/articles/s41...

Get the word out far and wide. New opportunity from the Simons Foundation in the Eco-Evo space. 2026 Simons Graduate Fellowship in Ecology and Evolution Awards, due July 31, 2025, only for incoming PhD students who plan to start their PhDs in Fall 2026. www.simonsfoundation.org/grant/simons...

Simons Graduate Fellowships in Ecology and Evolution www.simonsfoundation.org/grant/simons... Application Deadline July 31, 2025

E. coli prophages encode an arsenal of defense systems to protect against temperate phages: Cell Host & Microbe www.cell.com/cell-host-mi...

We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data        Generous starting package 💰 shorturl.at/FAk6n

I am working with ASM to re-launch the Central NY ASM Branch! 🧫🦠 We have funds allocated for us and now just need 25 signatures from ASM members in the geographic region in support of this branch. More info is in the form and also I’ve attached a FAQ sheet. docs.google.com/forms/d/e/1F...

Let's dive into this a bit. A short and very incomplete thread on US Forest Service research. 1/

Viewpoint in JAMA details the consequences of the proposed cuts to NIH: ❌15% reduction in new therapies ❌reduction in life expectancy by 83M life years in the US = $8.2T ❌loss of $51B in economic output annually All to save $20B annually. The math ain't mathin.' jamanetwork.com/journals/jam...

“Our calculations suggest that the proposed budgetary cuts to the NIH will create a social cost that is 16 times greater than the savings that the administration is attempting to achieve.” ITS 👏🏼 BAD 👏🏼 FOR 👏🏼 BUSINESS 👏🏼

🇨🇦🚨Job Alert🚨🇨🇦 Canada Excellence Research Chair (C$5 or C$10M, 8 yr budget) U Toronto, Dept of Biochem/LabMedPath *Was just told they're looking for a structural biologist using cryoEM* (related to infectious disease?) Are you an established PI ready to move to 🇨🇦? research.utoronto.ca/funding-oppo...

The private sector will not fill the gaps. The size of the cuts is too big, and the incentives does not align to do basic research or train the next generation of PhD students. donmoynihan.substack.com/p/are-univer...

We're hiring! Assistant/Associate Professor jointly appointed: Institute for Genome Sciences (IGS), the Institute for Health Computing (IHC), and the Greenbaum Comprehensive Cancer Center (UMGCCC) @medschool.umaryland.edu ‬ #Science #Cancer #Bioinformatics #Genomics Learn more: bit.ly/igsihcgcc

Last chance to apply for this faculty position in my department @healthsciences.mcgill.ca Assistant Professor (Teaching), Department of Global and Public Health We are looking for an expert in nutrition & Africa! Deadline: June 6, 2025 mcgill.wd3.myworkdayjobs.com/en-US/mcgill...

#amr #microsky

Opening for a #postdoc in the lab available immediately. Please spread the word. DETAILS HERE: jobrxiv.org/job/baylor-c... cc: #academicJobs #postdocJobs #microbiome #Celegans #organoids #IBD #PathSky #Medsky #AcademicSky 🧪 🧬 🦠

📢 Thrilled to announce the return of MoML @ MIT on Oct. 22 and that paper submissions are now open! Students & postdocs w/ accepted papers will be granted FREE admission to attend and have the chance at winning the Octavian-Eugen Ganea Prize for Best Paper! 🧵 #AcademicSky #compchem #drugdesign

The National Science Foundation budget proposal would be a devastating blow to American science. 240,000 fewer people would be involved in federally-funded science in fiscal year 2026, according to estimates in the document. nsf-gov-resources.nsf.gov/files/00-NSF...

📣 We are recruiting new group leaders in Innovative Biology! RNA biology Epigenetic regulation Cell cycle regulation Cancer, immunology Virology Application and information ⬇️ application.igmm.cnrs.fr @cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social

Write with Science Homecoming, and put your piece on the map: sciencehomecoming.com

How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)

The President's Budget request as released yesterday will gut scientific research. Why should you care? 1) Science is fundamentally a jobs program. Many 100,000s are employed to do science and work for you, the US taxpayer.

Super excited to release a huge evolution project on the works for many years: Evolution experiments synchronized across climates to understand rapid adaptation Preprint: doi.org/10.1101/2025... All data available: www.grene-net.org/data #MOILAB @ucberkeleyofficial.bsky.social @hhmi.org 🧵👇

90% of doing science is being open to new ideas.

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We have NASA's proposed budget for FY26, and it is brutal to science. Earth science would be cut by more than half. Astrophysics (like JWST, Hubble) by nearly two-thirds. Full details at www.nasa.gov/fy-2026-budg...

Presidential budget is out. Here's NSF. Biggest cut, by amount, is $1 billion, or 66.8%, from MPS (Physics & Math directorate). nsf-gov-resources.nsf.gov/files/00-NSF...