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microbegrrl.bsky.social
Microbiome, drugs, phages, ecology, AI, the Bronx
40 posts 3,174 followers 1,817 following
Prolific Poster

Earth system models are plagued by uncertainties in the response of microbes to climate change. We leveraged metabolic insights from genome scale models when coupled to an ocean model in this new exciting work 🌊 www.science.org/doi/full/10....

My latest @newscientist.com cartoon

New pre-print out \o/ All about CRISPR, metagenomes, and what you learn when you collect (a lot of) spacers from natural communities, with @apcamargo.bsky.social @urineri.bsky.social @lhug.bsky.social but also Uri Gophna, Nikhil George (not on Bsky I think) & others at JGI doi.org/10.1101/2025...

The Wadsworth Center is expanding it's research focus on #virology /vector-borne diseases! www.asmcareerconnections.org/job/research-scientist-5-g-31/78488664/ This is a unicorn assistant prof equivalent position with 12-month hard money salary and no teaching commitments (!) Reposts appreciated 🙏

How can we build a general theory of mutualistic communities? After five years, we finally completed a new Neutral Theory of Cooperation that is fully solved analytically and displays remarkable properties @jordipinero.bsky.social @artemyte.bsky.social @manlius.bsky.social arxiv.org/abs/2506.09737

Hello everyone! I am pleased to share information on the first ever Computational Structural Virology Symposium, conducted August 4th on zoom and highlighting work in this emerging field. You can register for this event here: forms.gle/CNiqskMwQEuV.... Please re-post!

Our paper in @science.org 👉🏽 www.science.org/doi/10.1126/... is accompanied by an especially thoughtful perspective by Carey Nadell and Chris Marx 👉🏽 www.science.org/doi/10.1126/...

Thrilled to see our review out in @natrevimmunol.nature.com together with my amazing mentors @jfcryan.bsky.social and Ger Clarke. @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social @uccresearch.bsky.social www.nature.com/articles/s41...

Thrilled to share our new paper in @science.org describing our discovery that bacteria can switch from competitors to bonafide predators when resources run dry—arming nanoscale “spears” (T6SS) to stab & consume neighbours. www.science.org/doi/10.1126/... #MicroSKy #Microbiology

Postdoc Insights from the Vienna BioCenter - Hear it directly from our fellows! The VIP³ call is open – apply now for a fully-funded, three-year postdoctoral fellowship in an interdisciplinary environment. Apply here: training.vbc.ac.at/post-docs/vi... #VBCPostDoc

“The search is on for 25 researchers from around the world in Lund University’s largest ever international recruitment drive. The main focus will be on AI research and other areas in which the University has a strategic focus.” www.lunduniversity.lu.se/article/lund...

‘Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees https://go.nature.com/3ZYip4X

Nature research paper: Metabolic adaptations direct cell fate during tissue regeneration https://go.nature.com/4l4GP5c

Modulating levels of a mitochondrial metabolite can direct intestinal stem cells to specialise for absorption or secretion https://go.nature.com/3ZrJ0HI

Check out the new pre-print from our lab on phage-assisted evolution of light-switchable, allosteric proteins. Congrats to first author @neuroscinikolai.bsky.social, co-corresponding author @jmathony.bsky.social and everyone from the @niopeklab.bsky.social involved! www.biorxiv.org/content/10.1...

Excited to share my main PhD work is finally out! 🥳 We built a phage-assisted evolution platform to evolve allosteric protein switches (POGO-PANCE) and introduce cumulative, targeted mutations/Indels (RAMPhaGE)! See how we evolved ultra-strong, light-switchable AraC variants 🌚🌞

I’m happy to announce our publication in @CMIJournal.bsky.social , focusing on emerging pathogenic E. coli O80:H2 and the role of humans as a potential reservoir for these atypical « hybrid » strains #ecoli #stec #expec #genomics #reservoir www.clinicalmicrobiologyandinfection.com/article/S119...

Nature research paper: Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III https://go.nature.com/44eE3Va

New @fwf-at.bsky.social CoE Microplanet Publication in NatureComms! @theviktoriaeffect.bsky.social from the lab of @chmoei.bsky.social @medunigraz.at profiled the proteome & metabolome of extracellular vesicles from key gut archaea, revealed immune-stimulating capacities and unique molecular cargo.

Evolution of gene order in prokaryotes is driven primarily by gene gain and loss www.pnas.org/doi/abs/10.1... #jcampubs 🌊

🚀 Our paper on the updated PrankWeb, a web app for protein binding site prediction using P2Rank, is out in @narjournal.bsky.social. Now with docking integration! 👨‍💻 Try it: prankweb.cz 📄 Paper: doi.org/10.1093/nar/... 💻 GitHub: github.com/cusbg/prankweb Developed at @cusbg.bsky.social

Two tenure-track positions at Amherst College www.amherst.edu. apply.interfolio.com/168795 (molecular genetics and biochemistry) apply.interfolio.com/168794 (molecular/cellular neurobiology)

2030STEM in partnership with Burroughs Wellcome Fund (BWF) is building a new, catalytic resource to advance the careers of early to mid-career STEM researchers and professionals who are motivated to build an inclusive STEM ecosystem. Get more informarion at 2030stem.org/fellowship-1

I'm happy to announce the latest release of the GlobDB, available at globdb.org. The GlobDB is a database of "species dereplicated" microbial genomes, and as of release 226 contains twice the number of species-representative genomes (306,260) than the latest GTDB release.

🦑🌊🧪 Please share among your networks, a Research Fellow post in #Ocean Dynamics and Floating Offshore #Wind Consequences on Key Ecosystem Drivers in the Celtic Sea working with me, @alexnimmosmith.bsky.social & @peterimiller.bsky.social tinyurl.com/44x66b5z #PlanktonImaging #RemoteSensing #AUVs

In her new book, published today, neuroscientist @nicolecrust.bsky.social takes a bird's-eye view of where the neuroscience community is currently and where it needs to go to solve some of the field’s biggest questions. #neuroskyence www.thetransmitter.org/community/el...

New genome announcement from our team: Draft genome sequence of Desulfobacterota strain M19, a mesophilic sulfur-disproportionating bacterium from a #DeepSea hydrothermal vent on the Mid-Atlantic Ridge journals.asm.org/doi/10.1128/... #Bacteria #Microbes #Genomics #HydrothermalVents #Extremophiles

"These are scientists, physicians, epidemiologists & other experts who are honored to serve their country because they care deeply about public health." @richbesser.bsky.social in defense of #ACIP and on the risks posed by political interference in its critical work. www.statnews.com/2025/06/10/a...

Today, my NIH colleagues and I did something scary but really important. We spoke up about egregious harms we are seeing happen to research participants and public health through thoughtless and politicized policies at NIH. 🧵1/3 apnews.com/article/nih-...

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

We have two new positions, a PhD and a Post doc at #InstituteofBiologyLeiden within our @microclockerc.bsky.social #ERCSyG project to discover interaction of #circadianclocks between Bacillus subtilis and Arabidopsis please share these with your network! 🙏 links below👇 [1/3]

Big day for the Gurney lab, first paper from the lab is now published. @sczerwinski.bsky.social led this work and answered a simple question does phage steering work when other bacteria are around? Tldr: yes! journals.asm.org/doi/epub/10....

I’ve written threads about the GBR-MGDs pMAGs, but it also contains viruses (vMAGs), including a monophyletic clade of marine Crassvirales, chromosome-level eukaryote eMAGs, and putative plasmids. We wanted a holistic DB. One problem: some key software appear to break with long reads. A 🦠 🧵.

www.votervoice.net/mobile/ASMUS... From @asm.org

Our newest special issue is now live! Check it out to discover more about diverse and beautiful Fungi🍄🍄‍🟫🍄 On the cover: the fly agaric, Amanita muscaria, releasing its spores in the early morning light. www.cell.com/current-biol...

New preprint "Drivers of genetic diversity across the marine tree of life" out lead by my former postdoc Rachel Toczydlowski, along with @reidbrennan.bsky.social, Joanna Kelley, Jamie Pringle, @seaprof.bsky.social, and @johnwares.bsky.social. www.biorxiv.org/content/10.1...

What comes next with reinforcement learning Scaling RL, sparse rewards, continual learning, and the progress wall when pretraining really stops. www.interconnects.ai/p/what-comes...

Trichodesmium metaproteomes reflect the differential influence of resource availability across ocean regions academic.oup.com/ismej/advanc... #jcampubs 🌊

Official accounts for SMBE and affiliated journals are now on Bluesky: ▫️ Society for Molecular Biology and Evolution @official-smbe.bsky.social ▫️ Molecular Biology and Evolution @molbioevol.bsky.social ▫️ Genome Biology and Evolution @genomebiolevol.bsky.social Starter Pack: go.bsky.app/2xnyMrS

🎙️I am thrilled to share this episode of #MattersMicrobial hosted by @markowenmartin.bsky.social. @symbionticism.bsky.social and I talk about One Health Microbiome Sciences and what is next for the microbiome research field! 🦠🌏

For all the microbiologists out there. asm.org/advocacy

New STAT story about NIH rescinding the institution-wide anti-DEI term and condition that had been added to Notices of Award. www.statnews.com/2025/06/09/n... 1/n

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪 www.richmondscientific.com/how-a-discov...

Job vacancy as senior scientist on #fluorescent #microscopy (incl confocal and high resolution) open at University of Vienna! Apply until June 15: jobs.univie.ac.at/job/Senior-S...

🚨BREAKING: 300+ NIH employees call out the harm of censorship & politicized science in scathing email to Bhattacharya, demanding an end to political interference, a lift on funding freezes, & rehiring of fired staff whose work saves lives. This is historic - insiders are blowing the whistle. 🧵(1/5)

CrossFilt: A Cross-species Filtering Tool that Eliminates Alignment Bias in Comparative Genomics Studies www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/kennethabarr...

I'm thrilled to share the newest paper from the Yang Lab! Ever wonder how bacterial metabolism affects antibiotic resistance #AMR? In this study, Barry Li, a former MD/PhD student in the lab, took on this question using a systems and #synthetic_biology approach. 1/n www.nature.com/articles/s41...

RFK Jr says he's dismissing all 17 members of CDC's vaccine advisory committee (ACIP) and will appoint new members, calling a number of them "last-minute appointees" of the Biden administration. HHS still says it plans to hold the next ACIP meeting June 25-27 www.cnn.com/2025/06/09/h...