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Much of biology remains hidden, especially the proteome. Jeff Nivala explores progress toward Oxford Nanopore-based single-molecule protein sensing — offering a path to decode proteins like DNA and transform our understanding of cellular machinery. #NanoporeConf

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With organ shortages critical, Brendan explores gene-edited pig transplants & blood-based monitoring. He describes how Oxford Nanopore technology offers a rapid, minimally invasive method – paving the way for faster, safer, & more accessible transplants. #NanoporeConf

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Cost-effective, fast, and accessible. Anna Flavia Peres shares how Oxford Nanopore sequencing could offer vital potential to characterise rare paediatric germ cell tumours in regions with limited infrastructure.

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Robustness and scalability matter in clinical genomics. Respiratory metagenomics has shown us what’s possible —but to scale, we need a method that’s robust, transferable, and standardised. That’s where Judith Breuer believes Oxford Nanopore comes in: flexible, scalable, and ready to roll out.

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Think of it as a genomic radar shield. With UK government backing, Ian shares how Oxford Nanopore sequencing is being implemented across hospitals in the UK — not just for potential diagnostics, but for biosurveillance and biosecurity. Ready to detect new pathogens and respond to future pandemics.

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Make sure to save the date for next year's London Calling! #NanoporeConf

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Everything we’ve looked for so far, we’ve been able to detect. Some leukaemia patients still lack a defined subtype — leaving clinicians with few options but aggressive treatment. But with Oxford Nanopore sequencing, Steven Hair believes we could unlock those missing diagnoses. #NanoporeConf

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A breakthrough moment in brain infectious. Faced with a mystery infection, Judith Breuer sequenced a biopsy sample—and identified a pathogen never before linked to brain infections. Find out more. #NanoporeConf

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Our spotlight winner, Ruben Cools, presented his full talk exploring how they are bridging genotype and phenotype through long Oxford Nanopore read, single-molecule multiomics. #NanoporeConf

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For rare disease cases, speed and answers matter. Danny shares how, with nanopore sequencing, we can rapidly investigate suspected genetic conditions—zooming in on key genes & regions to find what others may have missed. With the potential to say to families: Here’s what we found. #NanoporeConf

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Why wait weeks for a diagnosis? Danny Miller discusses the future potential of Oxford Nanopore sequencing, and how clinicians could get actionable results within hours—not days or weeks. No need to batch samples. Same-day sequencing, same-day answers.

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Sebastian shared how Oxford Nanopore technology adaptive sampling characterises complex genomic regions, encompassing SVs, repeat expansions, high-homology regions, CNVs and more behind disease - resulting in a time and cost-effective solution. #NanoporeConf

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Nate shares how they are solving unanswered questions with Oxford Nanopore technology by unlocking “so much more in our genome than previously before”. Watch how this is providing novel information about rare diseases. #NanoporeConf

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Ian Abbs shared how we're entering a new era in disease diagnosis, biosurveillance & biosecurity. After 6 years of metagenomic development, he team is unlocking rapid, clinically relevant pathogen detection—directly from human samples

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Eva Maria Novoa shared how the RNA 004 chemistry is unlocking questions we couldn’t answer before — improved flow cell stability and higher throughput is enabling her to push the boundaries of RNA sequencing. #NanoporeConf

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Lennart Kester showcased their deep-learning tools, that combined with Oxford Nanopore sequencing, classify paediatric tumours in under two hours – potentially enabling same-day, cost-effective and intraoperative characterisation in the future. #NanoporeConf

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Sissel Juul shared how Oxford Nanopore is setting the 'gold standard' as a single platform for telomere-to-telomere sequencing, with Sean McKenzie showcasing updates in assembly models providing contiguous, accurate and cost-effective T2T genomes. #NanoporeConf

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Ira Deveson discusses how they are using Oxford Nanopore sequencing as a single technology to provide genome assemblies to detect complex genomic regions, providing insights into underrepresented populations, rare disease and more. #NanoporeConf

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#NanoporeConf Lakmal Jayasinghe ONT is the only sequencing technology that detects RNA modifications directly. They're now up to 8 modifications that can be detected simultaneously. [This is something I think ONT should be shouting from the rooftops every day] RNA barcoding is in beta testing.

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In the studio, Matt Loose shares how: “Surgeons were literally knocking, saying I’ve got a patient today. Once people see what’s possible, they start to believe it — and get excited.” when talking about his new CNS tumour profiling method.

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Judith Brewer shared how their faster metagenomic method using Oxford Nanopore technology can detect AMR with the future potential to enable early, targeted treatment for brain, blood, & respiratory infections & reduce antibiotic use in critical care. #NanoporeConf

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Missed our flow cell loading demo in the last break? Don't worry, join us at lunch in the live lounge to gain hands-on experience and tips on how to load an Oxford Nanopore flow cell. #NanoporeConf

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Absolutely brilliant work at GOSH on targeted rapid metagenomics for same day results on respiratory infections at a hospital. 30 new centres across the UK to adopt this. #nextgen medicine. #Nanoporeconf

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We caught up with Tilda and Alimat from the 22,000 genome project. They discussed the robustness of nanopore data, scaling for 100s of samples and the ability to sequence even low-quality samples. #nanoporeconf

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At London Calling, Rosemary Sinclair Dokos and Lakmal Jayasinghe shared how we’re doubling down on what matters: delivering a future-ready platform with proven performance across DNA, RNA, and now proteins. Click here to discover what’s new – and why it matters: nanoporetech.com/news/london-...

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Back a London Calling 10 years after my first #NanoporeConf

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Amazing time to be working with @nanoporetech.com sequencing! The pace of innovation in this network of researchers is astonishing! #NanoporeConf

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Oxford Nanopore sequencing will be ubiquitous for multiomics….and the next step is proteomics. First panel-based proteomics assays, before driving towards full protein sensing in the future. #nanoporeconf

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Oxford Nanopore delivers industry-leading RNA sequencing with higher throughput, now outperforming alternate technologies. With direct RNA and cDNA workflows, it’s built for drug discovery, QC, and RNA applications beyond mRNA vaccines. #nanoporeconf

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We’re targeting 200 Gb per flow cell — powered by new chemistry, smarter pores, AI-driven basecalling & new conditions. All designed to cut cost-per-genome while scaling large-cohort sequencing.

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With significant ML advances, Dorado & MinKNOW now power built-in accurate variant calling, default methylation detection & short fragment mode. Adaptive sampling & T2T assemblies are production-ready — enabling faster, richer, more meaningful insights.

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We’re scaling innovation with purpose. This means: -Consolidation of devices & chemistry -Fewer & more robust launches. -Software-led performance improvements -Industry-standard pricing -✔️ Guaranteed outputs. ❌Theoretical maximums #nanoporeconf

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Methylation assists tandem repeat expansion estimation from @nanoporetech.com sequencing using strcount. #NanoporeConf

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Javeria Aijaz shares how the #MinION is enabling more accessible, streamlined, and accurate leukaemia identification - with the potential to be used across a range of critical applications where current technology falls behind.

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Kim shared how their scalable, long Oxford Nanopore read sequencing approach uncovered SVs, gene expression, & epigenetic regulation in neurodegenerative disease cohorts, offering new insights into Alzheimer’s and Parkinson’s risk across diverse populations.

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After her talk at #nanoporeconf, Nathalie Kingston joined Zoe in the studio to discuss how, for us to truly understand complex human diseases, we need to sequence large, diverse cohorts—and detect all variants.

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⁦Boston Children’s Hospital‬⁩ showing DNA from samples in a fridge can be successfully assessed for methylation at #nanoporeconf 🧪

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By targeting cognitive traits, rare diseases, and eating disorders, Nathalie Kingston and Kathy Stirrups’ pipeline has uncovered novel genetic variants—reshaping how we assess neurodegenerative disease risk.

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Collaboration is a vital part of the transformative research achieved by the Nanopore Community. That is why events like London Calling, bringing people together, are so important. #nanoporeconf

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Gordon welcomed us to London Calling, highlighting how the Oxford Nanopore community is right at the heart of the fourth industrial revolution. #NanoporeConf

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The first Poster Networking Session of London Calling 2025 is about to start! Head to the poster area now to explore cutting-edge science and connect with presenters. See you there! #NanoporeConf nanoporetech.com/about/events...

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Your speakers for London Calling 2025! #NanoporeConf

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Welcome to London Calling 2025! #NanoporeConf

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Over 14,000 publications. In areas making a real impact. One Community, driving discover. #nanoporeconf

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Live from London Calling 2025! Speakers, attendees and the Oxford Nanopore crew are starting to fill into Old Billingsgate! Ready for Gordon to kick things off for the 11th time! Make sure you keep your posts coming using: #nanoporeconf

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