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Every year there so many amazing @nanoporetech.com updates at London Calling. Here I'll focus on some of my top picks for Microbiology & Infectious Disease 🦠 First, we saw how the technology continued to advance research in 2024 with ~2/3 of ONT publications in micro/infectious #nanoporeconf

submitted 15 days ago • 1 comment

🧪 I will be presenting some of my research on the oral microbiome at @nanoporetech.com WYMM tour: Bay Area This coming Thursday June 5th. I hope to see you there! 🦷🧫🫡 nanoporetech.com/about/events...

submitted 9 days ago • 0 comments

Did you miss Dr. Michael Wiley’s (@unmc.bsky.social) talk at #nanoporeconf? Watch it now online: nanoporetech.com/resource-cen... In it, Dr. Wiley demonstrates the use of BugSeq in Nebraska for outbreak detection and investigation. #PublicHealth #AMR #LondonCalling2025 @nanoporetech.com

submitted 8 days ago • 0 comments

🚨 We’re hiring ! 🚨 Join our cutting-edge research team as a molecular biologist at @nanoporetech.com HQ in Oxford. Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI 👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...

submitted 5 days ago • 0 comments

Got a chance to take the @nanoporetech.com hyp(er accuracy) model for a spin. Pretty decent improvement in read quality 🚀 but expect to spend quite some more GPU hours 😉 (Reads were mapped with minimap2 and identity scores from nanoplot were used for phred score calculations)

submitted 3 days ago • 3 comments

Oxford @nanoporetech.com hyper model vs sup. Better Q-scores by simply better modelling and more AI compute.

submitted 3 days ago • 0 comments

With all that is happening it is very exciting to see the Price Lab's very first, in-house, Oxford Nanopore direct RNA seq running! Not bad for a ~3 year expired flow cell!

submitted 8 days ago • 2 comments

SWARM (Single-molecule Workflow for Analysing RNA Modifications) detects pseudouridine, m6A, and m5C on individual molecules from direct RNA nanopore signals (in both chemistries RNA002 and RNA004) github.com/comprna/SWARM see more on poster P2-396 at #rna2025 #RNA25 #RNAmods

submitted 8 days ago • 1 comment

Recombinases your thing? In the latest from my lab, Veronica Greco shows how @nanopore sequencing + automated liquid handling provides the perfect platform for characterising these systems at scale! Awesome collaboration with @jennbrophy.bsky.social @sarah-guiziou.bsky.social doi.org/10.1101/2025...

submitted 9 days ago • 1 comment

Much of biology remains hidden, especially the proteome. Jeff Nivala explores progress toward Oxford Nanopore-based single-molecule protein sensing — offering a path to decode proteins like DNA and transform our understanding of cellular machinery. #NanoporeConf

submitted 15 days ago • 0 comments

With organ shortages critical, Brendan explores gene-edited pig transplants & blood-based monitoring. He describes how Oxford Nanopore technology offers a rapid, minimally invasive method – paving the way for faster, safer, & more accessible transplants. #NanoporeConf

submitted 15 days ago • 0 comments

Cost-effective, fast, and accessible. Anna Flavia Peres shares how Oxford Nanopore sequencing could offer vital potential to characterise rare paediatric germ cell tumours in regions with limited infrastructure.

submitted 15 days ago • 0 comments

Robustness and scalability matter in clinical genomics. Respiratory metagenomics has shown us what’s possible —but to scale, we need a method that’s robust, transferable, and standardised. That’s where Judith Breuer believes Oxford Nanopore comes in: flexible, scalable, and ready to roll out.

submitted 15 days ago • 0 comments

Think of it as a genomic radar shield. With UK government backing, Ian shares how Oxford Nanopore sequencing is being implemented across hospitals in the UK — not just for potential diagnostics, but for biosurveillance and biosecurity. Ready to detect new pathogens and respond to future pandemics.

submitted 15 days ago • 0 comments

Make sure to save the date for next year's London Calling! #NanoporeConf

submitted 16 days ago • 0 comments

Everything we’ve looked for so far, we’ve been able to detect. Some leukaemia patients still lack a defined subtype — leaving clinicians with few options but aggressive treatment. But with Oxford Nanopore sequencing, Steven Hair believes we could unlock those missing diagnoses. #NanoporeConf

submitted 16 days ago • 0 comments

A breakthrough moment in brain infectious. Faced with a mystery infection, Judith Breuer sequenced a biopsy sample—and identified a pathogen never before linked to brain infections. Find out more. #NanoporeConf

submitted 16 days ago • 0 comments

Our spotlight winner, Ruben Cools, presented his full talk exploring how they are bridging genotype and phenotype through long Oxford Nanopore read, single-molecule multiomics. #NanoporeConf

submitted 16 days ago • 0 comments

For rare disease cases, speed and answers matter. Danny shares how, with nanopore sequencing, we can rapidly investigate suspected genetic conditions—zooming in on key genes & regions to find what others may have missed. With the potential to say to families: Here’s what we found. #NanoporeConf

submitted 16 days ago • 0 comments

Why wait weeks for a diagnosis? Danny Miller discusses the future potential of Oxford Nanopore sequencing, and how clinicians could get actionable results within hours—not days or weeks. No need to batch samples. Same-day sequencing, same-day answers.

submitted 16 days ago • 0 comments

Sebastian shared how Oxford Nanopore technology adaptive sampling characterises complex genomic regions, encompassing SVs, repeat expansions, high-homology regions, CNVs and more behind disease - resulting in a time and cost-effective solution. #NanoporeConf

submitted 16 days ago • 0 comments

Nate shares how they are solving unanswered questions with Oxford Nanopore technology by unlocking “so much more in our genome than previously before”. Watch how this is providing novel information about rare diseases. #NanoporeConf

submitted 16 days ago • 0 comments

Ian Abbs shared how we're entering a new era in disease diagnosis, biosurveillance & biosecurity. After 6 years of metagenomic development, he team is unlocking rapid, clinically relevant pathogen detection—directly from human samples

submitted 16 days ago • 0 comments

Eva Maria Novoa shared how the RNA 004 chemistry is unlocking questions we couldn’t answer before — improved flow cell stability and higher throughput is enabling her to push the boundaries of RNA sequencing. #NanoporeConf

submitted 16 days ago • 0 comments

Lennart Kester showcased their deep-learning tools, that combined with Oxford Nanopore sequencing, classify paediatric tumours in under two hours – potentially enabling same-day, cost-effective and intraoperative characterisation in the future. #NanoporeConf

submitted 16 days ago • 0 comments

Sissel Juul shared how Oxford Nanopore is setting the 'gold standard' as a single platform for telomere-to-telomere sequencing, with Sean McKenzie showcasing updates in assembly models providing contiguous, accurate and cost-effective T2T genomes. #NanoporeConf

submitted 16 days ago • 0 comments

Ira Deveson discusses how they are using Oxford Nanopore sequencing as a single technology to provide genome assemblies to detect complex genomic regions, providing insights into underrepresented populations, rare disease and more. #NanoporeConf

submitted 16 days ago • 0 comments

#NanoporeConf Lakmal Jayasinghe ONT is the only sequencing technology that detects RNA modifications directly. They're now up to 8 modifications that can be detected simultaneously. [This is something I think ONT should be shouting from the rooftops every day] RNA barcoding is in beta testing.

submitted 16 days ago • 1 comment

In the studio, Matt Loose shares how: “Surgeons were literally knocking, saying I’ve got a patient today. Once people see what’s possible, they start to believe it — and get excited.” when talking about his new CNS tumour profiling method.

submitted 16 days ago • 0 comments

Judith Brewer shared how their faster metagenomic method using Oxford Nanopore technology can detect AMR with the future potential to enable early, targeted treatment for brain, blood, & respiratory infections & reduce antibiotic use in critical care. #NanoporeConf

submitted 16 days ago • 1 comment

Missed our flow cell loading demo in the last break? Don't worry, join us at lunch in the live lounge to gain hands-on experience and tips on how to load an Oxford Nanopore flow cell. #NanoporeConf

submitted 16 days ago • 0 comments

Absolutely brilliant work at GOSH on targeted rapid metagenomics for same day results on respiratory infections at a hospital. 30 new centres across the UK to adopt this. #nextgen medicine. #Nanoporeconf

submitted 16 days ago • 1 comment

We caught up with Tilda and Alimat from the 22,000 genome project. They discussed the robustness of nanopore data, scaling for 100s of samples and the ability to sequence even low-quality samples. #nanoporeconf

submitted 16 days ago • 0 comments

At London Calling, Rosemary Sinclair Dokos and Lakmal Jayasinghe shared how we’re doubling down on what matters: delivering a future-ready platform with proven performance across DNA, RNA, and now proteins. Click here to discover what’s new – and why it matters: nanoporetech.com/news/london-...

submitted 17 days ago • 0 comments

Back a London Calling 10 years after my first #NanoporeConf

submitted 17 days ago • 0 comments

Amazing time to be working with @nanoporetech.com sequencing! The pace of innovation in this network of researchers is astonishing! #NanoporeConf

submitted 17 days ago • 0 comments

Oxford Nanopore sequencing will be ubiquitous for multiomics….and the next step is proteomics. First panel-based proteomics assays, before driving towards full protein sensing in the future. #nanoporeconf

submitted 17 days ago • 2 comments

Oxford Nanopore delivers industry-leading RNA sequencing with higher throughput, now outperforming alternate technologies. With direct RNA and cDNA workflows, it’s built for drug discovery, QC, and RNA applications beyond mRNA vaccines. #nanoporeconf

submitted 17 days ago • 0 comments

We’re targeting 200 Gb per flow cell — powered by new chemistry, smarter pores, AI-driven basecalling & new conditions. All designed to cut cost-per-genome while scaling large-cohort sequencing.

submitted 17 days ago • 0 comments

With significant ML advances, Dorado & MinKNOW now power built-in accurate variant calling, default methylation detection & short fragment mode. Adaptive sampling & T2T assemblies are production-ready — enabling faster, richer, more meaningful insights.

submitted 17 days ago • 0 comments

We’re scaling innovation with purpose. This means: -Consolidation of devices & chemistry -Fewer & more robust launches. -Software-led performance improvements -Industry-standard pricing -✔️ Guaranteed outputs. ❌Theoretical maximums #nanoporeconf

submitted 17 days ago • 0 comments

Methylation assists tandem repeat expansion estimation from @nanoporetech.com sequencing using strcount. #NanoporeConf

submitted 17 days ago • 0 comments

Javeria Aijaz shares how the #MinION is enabling more accessible, streamlined, and accurate leukaemia identification - with the potential to be used across a range of critical applications where current technology falls behind.

submitted 17 days ago • 0 comments

Kim shared how their scalable, long Oxford Nanopore read sequencing approach uncovered SVs, gene expression, & epigenetic regulation in neurodegenerative disease cohorts, offering new insights into Alzheimer’s and Parkinson’s risk across diverse populations.

submitted 17 days ago • 0 comments