nebanovich.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Latest news feature in @natbiotech.nature.com on recent developments in spatial biology to unravel disease mechanisms, with insights from experts in field. @aruthak.bsky.social @nebanovich.bsky.social @ai4pathology.bsky.social @jasmineplummer.bsky.social www.nature.com/articles/s41...

submitted 13 days ago • 0 comments

Really excited about this new work from Sam Hart (and joint with @kelleyharris.bsky.social) trying to disentangle mutational differences between groups of cancers. Check out Kelley's thread with the major results!

submitted 13 days ago • 0 comments

absolutely crushing

submitted 13 days ago • 0 comments

submitted 15 days ago • 1 comment

people need to internalize, very quickly, that federal research grants are a hypercompetitive contracting process not charity, and that what Uncle Sam gets in return for that money is American dominance in the future

submitted 16 days ago • 165 comments

say it again: 4 million people work in higher ed, the largest employer in 10 states, second largest employer in 10 more, and in 60 of the 100 biggest cities ROI for NIH and NSF for local economies is conservatively 4x, often close to 10x demolishing higher education is economic sabotage

submitted 16 days ago • 70 comments

As a former @hhmi.org Gilliam fellow, I’m deeply disappointed to see HHMI cancel the Hanna Gray this year and pause all competitions. @leslievosshall.bsky.social, Erin O’Shea — this was a moment to lead with vision, not retreat.

submitted 17 days ago • 6 comments

All NIH and NSF grants for my entire team--and for all of Harvard, I guess?--have been terminated. As provocative as that sounds, the practical effect is probably not much. Everything was already frozen. 🤷‍♂️ On the upside, it makes tracking terminated grants easier. No more guesswork at Harvard!

submitted 18 days ago • 27 comments

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

submitted 20 days ago • 146 comments

All of my NIH grants terminated this afternoon along with those of all of my colleagues including big (and extremely successful) P01 grants.

submitted 18 days ago • 38 comments

Happy to share the published version of Omar & Sayan’s paper. We generated a DNA-damage-associated cardiomyocyte protein co-expression network to gain insights into tolerance to genetic variation and disease. www.sciencedirect.com/science/arti...

submitted 24 days ago • 0 comments

New preprint! My (now former) postdoc @kvastad.bsky.social led this integration of GWAS and spatial transcriptomics (ST) data to identify tissue structures with enrichment of disease-implicated genes = likely causal drivers of disease biology. www.biorxiv.org/content/10.1...

submitted 29 days ago • 4 comments

🎉 This paper has been a long time and a labour of love (and hardship) for multiple group members, but, finally: we MPRA'ed 25k introgressed variants (Denisovan and Neanderthal) segregating at allele frequencies > 0.15 in humans today to evaluate their potential to regulate gene expression.

submitted 29 days ago • 5 comments

Why are they trying to kill the goose that lays the golden eggs? #WithoutNSF the US would not be at the forefront of science innovation in the world. #SaveNSF #StandUpForScience www.nsf.gov/policies/doc...

submitted 32 days ago • 9 comments

This new guidance is yet another step closer towards an isolationist, diminished view of American science. Changing rules on the fly wastes time & effort and undermines the pipeline of discovery and innovation. Unacceptable & inexcusable (again): grants.nih.gov/grants/guide...

submitted 32 days ago • 1 comment

NEW: The NIH has begun terminating grants for active projects studying gender identity, DEI, environmental justice, climate change, among other topics. At least 16 termination letters have already been sent — and hundreds more are coming, people inside NIH tell me. www.nature.com/articles/d41...

submitted 89 days ago • 37 comments

Current NIH funding slump represents: - Research labs closing - PhD students abandoning their dreams. - Trial participants left to their own devices mid study. - A halt to scientific progress and innovation for cancer, chronic and infectious diseases. - Minority health research terminated. Etc.

submitted 33 days ago • 1 comment

The National Cancer Institute has disbanded its Board of Scientific Advisors — a group of experts that played a vital role in shaping the future of U.S. cancer research. Here’s why that matters. 🧵

submitted 34 days ago • 7 comments

There are few things as cost effective as Narcan, especially in a country where (entirely preventable) opioid overdoses have been a leading cause of death for years. For every 6 kits distributed 1 OD is prevented. The $56M in this grant trained >66K people and distributed >282,500 kits in 2024 alone

submitted 34 days ago • 164 comments

NIH just posted a Notice with the new Terms and Conditions... grants.nih.gov/grants/guide...

submitted 42 days ago • 16 comments

Looks like ~9,000 people made it to the Bernie/AOC rally in #Missoula yesterday. Considering it was a Wednesday in the middle of the day, that’s super impressive. Comparing it to the prior records: the 10k Women’s march was on a Saturday and Trump’s BZN 8k rally was at night. #FightingOligarchy

submitted 46 days ago • 0 comments

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

submitted 49 days ago • 1660 comments

I was in Boston a few weeks ago and my colleagues at Harvard were looking to their leadership for this type of response. Way to go Harvard! www.harvard.edu/president/ne...

submitted 49 days ago • 0 comments

Free idea: a website where you enter the name of your disease/injury/condition/procedure and get shirts, stickers, signs, etc. with “NIH grant number X saved my life.”

submitted 54 days ago • 15 comments

There's nothing like a puppy break to rejuvenate and recharge after a productive week 🐶 And thankfully, #ATS2025 has got that covered! The puppies will return to the exhibit hall this year for attendees to enjoy a little paws-itivity!🐾 Register today! conference.thoracic.org/attendees/re...

submitted 59 days ago • 0 comments

I’m excited to share our new preprint, “Overcoming myeloid-driven resistance to CAR T therapy by targeting SPP1.” In this study, we identified and targeted a macrophage population shaping the tumor microenvironment in GBM, greatly increasing the efficacy of CAR T therapy. doi.org/10.1101/2025... 1/7

submitted 61 days ago • 1 comment

Excited to share our new work exploring strategies to overcome resistance to CAR T cell therapy in solid tumors. Using scRNA-seq, mouse models, and functional studies, our work points to SPP1 signaling in the TME as a critical component of this resistance. www.biorxiv.org/content/10.1...

submitted 61 days ago • 1 comment

Had a great visit to BWH/Harvard yesterday. Enjoyed spending the day talking fun science with the the great folks in the Channing. Thanks for the invite @asaferali.bsky.social! Had to snap a quick shot of this old add displayed on the wall highlighting how horrible tobacco companies were.

submitted 62 days ago • 1 comment

Excited to share Ruqian has developed a package for this transcript based niche analysis. Check out the preprint and the package! This is a flexible approach and we're working on extending this for other spatial analyses! @davisjmcc.bsky.social www.biorxiv.org/content/10.1...

submitted 68 days ago • 0 comments

New lab photo(s)! First time the whole lab was together in person in ~4 years. Had the bright idea to stick us all in the freight elevator on the way down for our photo shoot.

submitted 69 days ago • 0 comments

SpatialRNA: a Python package for easy application of Graph Neural Network models on single-molecule spatial transcriptomics dataset www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/pyg-team/pyt...

submitted 70 days ago • 0 comments

I just had my busiest week in lab since finishing my PhD, and I loved every second of it. This government can attack diversity and science and education all they want, but they’ll NEVER take away my passion for science and my responsibility to use my education to research cures for human disease

submitted 73 days ago • 0 comments

It's not every day your work is on the cover of a magazine. Congrats to first author and TGen post-doc, @annikavannan.bsky.social, @nebanovich.bsky.social, his team and collaborators on earning the cover of this month's publication of @naturegenet.bsky.social 🧬 🫁 👏 Photo courtesy of Nature Genetics

submitted 75 days ago • 1 comment

When I hear people shrug and say "Columbia/The Ivies will recover", I'm not worried about the institutes. I'm worried about people like this and the cascade of lives their work would have benefitted. Shattering.

submitted 76 days ago • 0 comments