pietraslab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

📣 New pre-print from the lab: 👉 “Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML #GBM 📝 Read the #BioRxiv here: doi.org/10.1101/2025...

submitted 29 days ago • 2 comments

🚨 We’re hiring a bioinformatics-focused PhD student for our ERC-funded project on recurrent GBM! Focus: tumor-supportive microenvironment 🔬 Experience with scRNA-seq, spatial transcriptomics & Python/R a plus. Must be self-motivated & driven. DM for details! Repost=❤️ lu.varbi.com/en/what:job/...

submitted 35 days ago • 1 comment

🚨 We’re hiring a bioinformatics-focused PhD student for our ERC-funded project on recurrent GBM! Focus: tumor-supportive microenvironment 🔬 Experience with scRNA-seq, spatial transcriptomics & Python/R a plus. Must be self-motivated & driven. DM for details! Repost=❤️ lu.varbi.com/en/what:job/...

submitted 35 days ago • 1 comment

Just a few spots left for this exciting symposium on brain tumor plasticity—grab yours (free of charge!) before they're gone! 🚨

submitted 38 days ago • 0 comments

+1

submitted 45 days ago • 0 comments

👋We have 2 amazing projects: A) basic molecular regulation of the LN lymphatic vasculature & B) lymphatic metastasis with new models & human samples describing completely new phenomena - both projects with solid preliminary data to build on. Open for interested postdoctoral scientists 📩

submitted 48 days ago • 0 comments

Join us for innovative explorations of the tumor microenvironment🔬 Learn cutting-edge technologies and grow in a dynamic environment💡 The postdoc will work alongside a doctoral student from @adaptmet.bsky.social, gaining access to collaborative partners across 🇪🇺. Apply now👇 tinyurl.com/4mby45hf

submitted 57 days ago • 1 comment

I'm delighted to host @ggargiul.bsky.social for a talk in the LUCC seminar series today. Medicon Village Auditorium @ 1.30 - you don't want to miss out if you're in Lund! Welcome!

submitted 72 days ago • 1 comment

Hot off the press! 🧬🔬 We developed in utero nano-injection to label & trace the mouse neural plate and otic placode using next generation single cell lineage tracing. We couple progenitors to mature cell types in the CNS & resolve the lineages of cells in the hearing organ: doi.org/10.1126/scie...

submitted 76 days ago • 9 comments

📣 Online now! Our study shows how recurrent focal deletions constitute a mechanism by which cancer cells can dampen toxicity due to gene amplification. www.cell.com/cell-genomic... 🧵👇:

submitted 92 days ago • 2 comments

Huge congrats to @kpietraslab.bsky.social on this well-deserved recognition! 🙌🥳

submitted 101 days ago • 0 comments

"EMT favours the emergence of genomic-unstable, highly fit tumour cells, which strongly supports the concept of cell-state-restricted patterns of evolution" Exceptional work addressing a classic chicken & egg paradigm in cell-state-driven tumor evolution. Congrats Gianni, Luigi & teams!

submitted 105 days ago • 0 comments

Congratulations to winners of The Brain Prize 2025! Professors @michellemonje.bsky.social, @stanfordmedicine.bsky.social and @hhmi.org Investigator, and Frank Winkler, Heidelberg University Hospital, have pioneered the field of Cancer Neuroscience. Learn more: brainprize.org/winners/canc...

submitted 106 days ago • 1 comment

Exciting tech advance 4 cancer research: FFPE-CUTAC enables phenotype queries from archived FFPE tissues. This finds a striking correlation between hypertranscription of histones (but not ribosomal genes) & chromosome arm losses, hence, cancer evolution.

submitted 117 days ago • 1 comment

Come and join us at our annual meeting in Freiburg! There is still time to submit your abstract! Deadline 21.02.! 👇 www.matrixbiologie.de/annual-meeti...

submitted 129 days ago • 0 comments

At the Brain Tumor Microenvironment Symposium @institutducerveau.bsky.social, Sebastian Braun presented our comprehensive study of pericytes in GBM 🤩. Pericytes act as guardians of the peri-vascular niche to prevent malignant cell invasion, read more at www.biorxiv.org/content/10.1...

submitted 139 days ago • 0 comments

We're excited to be at the Institute du Cerveau in Paris for the brain tumor microenvironment symposium 🧠 Here's Pauline Jeannot with the first presentation of the day from the lab 🔥

submitted 140 days ago • 1 comment

We have been waiting impatiently but can finally share our latest efforts in understanding the biology of the TGF-beta type I receptor ALK1 (gene name ACVRL1), see graphical abstract in post and the full article here: www.jci.org/articles/vie... 1/6

submitted 154 days ago • 2 comments

End-of-the-year preprint & first 🧵 where the sky is blue! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?

submitted 170 days ago • 2 comments

The two Pietras labs @pietraslab.bsky.social @kpietraslab.bsky.social collide in a fierce game of Ping Pong. The losers fill all pipette tip boxes the next year 😜

submitted 183 days ago • 0 comments

I can't be more stoked to start my #scienceblue feed with this! OOPS WE DID IT AGAIN with @nabalabuic.bsky.social ! 🤩🤩🤩 And for the nerds, this is all in @rshiny.bsky.social ! #democratizescience #bigdataforall #ECMatrix

submitted 184 days ago • 0 comments

We are looking for future cancer researchers! The Advanced Cancer Biology course is offered at Lund University and provides both theoretical and practical preparation for doctoral studies in cancer research. Deadline for international admission: January 15, 2025. www.lucc.lu.se/education/ed...

submitted 204 days ago • 0 comments

1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...

submitted 203 days ago • 47 comments

Delighted to see this paper from Anna Blom's group published in its final form! 🎉 Huge congrats to @karolinasmolag.bsky.social and the entire team—another fantastic collaboration unraveling the roles of complement proteins in the GBM microenvironment. 👏🧠

submitted 204 days ago • 0 comments

Hello Bluesky, we are recruiting PhD students in cancer and metastasis biology! This is a fantastic program that brings together several leading European research institutes. Details here: adaptmet.eu/recruitment/

submitted 206 days ago • 0 comments

Meet our PhD student Rebecca! This year, she beat cancer AND published her first 1st-author paper on how hypoxia induces complement signaling in GBM, alters macrophage polarization, and how the C3-C3AR1 axis can be therapeutically targeted in GBM models. Check it out! insight.jci.org/articles/vie...

submitted 212 days ago • 0 comments

There are a lot of excellent Starter Packs available, but I didn’t see one focused on Neuro-oncology. If you want to be added to this list, please reply below! go.bsky.app/VgzHLtt

submitted 212 days ago • 25 comments

We love to explore unexpected findings 🤔 Check out our two latest studies detailing the unexplored expression of ALK1 in immunosuppressive macrophages and the critical role of pericytes as a paracrine signaling hub in GBM. www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

submitted 213 days ago • 0 comments

Cool new lineage tracing tool provides in vivo evidence that tumor regrowth following radiotherapy stems from cells that were hypoxic at the time of irradiation! www.sciencedirect.com/science/arti...

submitted 213 days ago • 1 comment

Our friends @kpietraslab.bsky.social made it over as well!

submitted 213 days ago • 0 comments

the undisputed MVP of brain tumor twitter just arrived!

submitted 213 days ago • 1 comment

Hi Bluesky! 👋 We're the Alexander Pietras Lab, exploring the complexities of the brain tumor microenvironment. We study how therapies like radiotherapy reshape it and seek innovative ways to outsmart tumors. Follow for updates on our discoveries, collaborations, and science-in-action snapshots! 🧠✨

submitted 216 days ago • 1 comment