pitarresilab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

I'm excited to share the lab’s new paper on PDAC-associated cachexia on bioRxiv today, led by star postdoc @nikitab.bsky.social “Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis” A 🧵 below, if you are interested... www.biorxiv.org/content/10.1...

submitted 10 hours ago • 1 comment

I'm not sure I will ever experience this again as a PI, but THREE trainees in the lab gave invited talks today at the UMass Chan GI Research Day. Congrats to @nikitab.bsky.social @calvinjohnsonio.bsky.social @jessicapeura.bsky.social! Cahexia-Metastasis-Immunosuppression....we do it all!

submitted 15 days ago • 0 comments

The 80-year recipe stoking America’s Prosperity: 1) Free-market capital investments in brilliant ideas… 2) enabled by Engineering Innovations… 3) based on Science Research in Universities… 4) funded by Grants from the US Government. It’s time more people understood this.

submitted 21 days ago • 388 comments

My trainee just sent me this notification from the NIH about a pending F31 application. We knew it was likely to come, but it still hurt to read the words.

submitted 32 days ago • 12 comments

Congrats to first author @skyeweisse.bsky.social and co-authors @jessicapeura.bsky.social @nikitab.bsky.social @calvinjohnsonio.bsky.social on our recent collaborative effort with the Foskett lab on the role of mitochondrial calcium and MCU in pancreatic cancer metastasis @cellreports.bsky.social

submitted 40 days ago • 1 comment

“Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity,” is now available at Cell Reports. MCU-KO blocks EMT & reduces metastasis in PDAC, reversed by Snail. @pitarresilab.bsky.social #sciencesky www.cell.com/cell-reports...

submitted 40 days ago • 0 comments

Article Mitochondrial Ca 2+ controls pancreatic cancer growth and metastasis by regulating ... - goo.gl/alerts/LVVbLH #GoogleAlerts

submitted 43 days ago • 0 comments

Congrats to @anirbanmaitra.bsky.social @linghua-wang.bsky.social and the rest of the team on this absolute tour de force to map plasticity in PDAC, in @nature.com today. So much exciting data to explore here! www.nature.com/articles/s41...

submitted 45 days ago • 0 comments

Congrats to grad student @calvinjohnsonio.bsky.social for being chosen for an oral presentation at the Immunology Microbiology Program (IMP) retreat!

submitted 50 days ago • 1 comment

Gov. Maura Healey came to UMass Chan Medical School on Tuesday to learn about the implications of cuts and delays to the Medical School’s NIH funding. “Institutions like UMass Chan are under threat." Watch the video to see what else Gov. Healey had to say: direc.to/nbsV #NIHfunding

submitted 52 days ago • 0 comments

Congrats to @nikitab.bsky.social for being selected to give a talk at the Cancer Cachexia Society meeting today! She did a great job representing the lab and showcasing her exciting project on the role of PTHrP in mediating PDAC-associated cancer cachexia.

submitted 59 days ago • 0 comments

www.thebaltimorebanner.com/economy/scie...

submitted 59 days ago • 0 comments

Absolutely terrible news.

submitted 66 days ago • 0 comments

Princeton has announced that it is considering selling approximately $320 million of taxable bonds. The bonds are a way for the University to raise short-term funds. The major credit-rating agencies rate University bonds AAA, the highest level of creditworthiness.

submitted 66 days ago • 32 comments

I’ve taken the Senate floor and will speak for as long as I’m physically able to lift the voices of Americans who are being harmed and not being heard in this moment of crisis. Watch here:

submitted 68 days ago • 11136 comments

This is absolutely devastating. My young lab has benefitted from a DOD Pancreatic Cancer Research Program Idea Development Award that allowed me to extend my research program in exciting new directions that wouldn't have happened without this critical support. Just terrible....

submitted 73 days ago • 1 comment

It feels weird to celebrate in this current climate, but really proud of my group for our paper getting accepted at Cell Reports, in collaboration with the Foskett lab at Penn! Congrats @jessicapeura.bsky.social @calvinjohnsonio.bsky.social @nikitab.bsky.social

submitted 86 days ago • 2 comments

Via pancan.org. Congress is voting on a bill that cuts Dep’t of Defense cancer research funding by more than 50% — devastating to #PancreaticCancer Research. Demand your reps approve a full-year FY25 Defense Appropriations Act that fully funds the Congressionally Directed Medical Research Program.

submitted 88 days ago • 0 comments

Accepted!

submitted 94 days ago • 0 comments

Anyone have experience doing phosphoproteomics with a company? There are many options out there, so looking to see if anyone had a good experience with a company. We have a relatively simple experimental design: Pancreatic cancer cell lines +/- our gene of interest (a kinase).

submitted 95 days ago • 1 comment

Some good-ish news from NIH “Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again” As far as I know, the timing for this is not clear, but I will be checking the Federal Register.

submitted 103 days ago • 17 comments

By crushing cancer research, what are Elon & Trump making more efficient? Their NIH funding cuts are illegal—so instead, they're suffocating the grant approval process for cancer researchers with so much red tape that labs & clinical trials will be forced to shut down.

submitted 103 days ago • 34 comments

SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers www.embopress.org/doi/full/10....

submitted 106 days ago • 0 comments

It’s like pricing 🚗s @ cost of material & labor Tooling, facilities, safety, QC, advertising, shipping etc: capped 80% ⬇️ cost Consumers save💰but co. is out of business in a week. No more cars Stupid business model Same analogy for govt-contracted maker of rockets and satellites Oh, wait…

submitted 117 days ago • 0 comments

Congrats to postdoc in the lab @nikitab.bsky.social for being awarded a Pancreatic Cancer Alliance Postdoc Fellowship!!

submitted 130 days ago • 0 comments

Welcome to the lab our 2 new rotation students, Ethan Chang @ethanhcchang.bsky.social and Janhavi Sawant @janhaviysawant.bsky.social . Head over to pitarresilab.com/team to learn more about them!

submitted 143 days ago • 0 comments

Excited to co-chair #ASBMB2025 with the incredible Dave Pagliarini! This year’s ASBMB meeting promises to showcase cutting-edge science, foster dynamic collaborations, & inspire new ideas. Don’t miss your chance to be part of it—register & submit your late breaking abstracts. t.co/UwgMdxBo15

submitted 148 days ago • 2 comments

Welcome Suheera Haq, our new undergrad from UConn, to the team! Head over to www.pitarresilab.com/team to learn more about her, her love for exploring national parks, and her passion for the NYT games!

submitted 155 days ago • 0 comments

Did you ever wonder why metastatic cancers often spread to the lungs? Amazing research from @ginevradoglioni.bsky.social! Many thanks to all collaborators, funders and patients. Wishing you all an enjoyable read and a happy new year and Ginevra a great next endeavor @salkinstitute.bsky.social

submitted 157 days ago • 5 comments

Manuscript resubmission due on Christmas Eve......

submitted 170 days ago • 1 comment

RNA sensing induced by chromosome missegregation augments anti-tumor immunity www.cell.com/molecular-ce...

submitted 170 days ago • 0 comments