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pjsaez.bsky.social
Husband - Dad of 2 - Scientist πŸ‡¨πŸ‡± Chilean expat. I love to study how cells walk & talk. PI of the @cellcommlab.bsky.social #CellMigration #CellComm #calciumsignaling #organelles πŸ§ͺπŸ”¬
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#FluorescenceFriday #Mitochondria, powerhouse of the #cell were labeled (cyan) and it's possible to visualize how they reach *every* corner to provide energy. All recorded under the microscope @cellcommlab.bsky.social #scicomm #sciencesky #microscopy #organelles @focalplane.bsky.social πŸ§ͺπŸ”¬

This is why we love #cell dynamics ! Look at this #macrophage branching exploring the surroundings videoed under the microscope This what immune cells do in our body in search of bacteria, viruses and death cells #microscopy #cellbio #sciencesky @focalplane.bsky.social @cellcommlab.bsky.social πŸ§ͺπŸ”¬

Very excited to share the first preprint from the lab: www.biorxiv.org/cgi/content/... We investigated neural crest migration all the way from head to tail of the Zebrafish embryo and we found their nuclei suffer dramatic deformations. Want to know of they cope with feeling squeezed? 🐟🐠🐟

50 Years of Cell Biology: German Society for Cell Biology Meeting, October 26 – 29, 2025 | Heidelberg, Germany Early bird registration deadline: June 15, 2025

πŸ‘‹ Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab! πŸ‘‰ deadline 20/06 πŸ‘‡ check it out www.godinholab.com

@syncellbiolab.bsky.social: Thanks for organising! #microtubules 🀩

#Science Bluesky, do your thing: We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas. Can you indicate some names to me?

I’m excited to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @science.org ! (link at end of 🧡)

It was a great @dgz.bsky.social session with a lot of #CellMigration and trafficking of #ImmuneCells Thanks to all the speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU

#CellMigration Join us today @dgz.bsky.social !! See you in 1 h (zoom id and password in the pic below)

100 years ago it was founded the most successful and popular football team in Chile πŸ‡¨πŸ‡±: #ColoColo βš½πŸ† This year I had the chance to be in, Valladolid, where David Arellano (the the founder of the club) died (Hotel Inglaterra). He died while playing for Colo-Colo. #centenarioalbo #ColoColo100

Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system There will be of course some #CellMigration of leukocytes ;) Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU

The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! πŸ§‘β€πŸ”¬πŸ§‘β€πŸ”¬πŸ§¬

Jueves, 20 de marzo ⏰ 12.30 SEMINARIO Ad Hoc en el #IIBmCSICUAM πŸ“™ Pablo J. SΓ‘ez de la University Medical Center Hamburg-Eppendorf (UKE), Alemania, darΓ‘ una conferencia πŸ—£οΈ"Decision-making during cell migration” @pjsaez.bsky.social @cellcommlab.bsky.social @csic.es @uam.es

New preprint out πŸ”₯πŸ”₯ on my postdoc work with @manuelthery.bsky.social and @lblanchoin.bsky.social about how we can create sustained dynamic steady states of actin network inside microscopic wells that contract "forever" without collapsing! A thread 🧡 www.biorxiv.org/content/10.1...

Hot from the press: #CellMigration #vesicles #organelles Jeppesen et al @mag2art.bsky.social lab introduce blebbisomes: organelle-rich motile vesicles, have immune checkpoint inhibitors, released by #cancer cells & used for #cellcomm @naturecellbiology.bsky.social www.nature.com/articles/s41... πŸ§ͺπŸ”¬

The next deadline for the JCS-FocalPlane Training Grants is Friday 7 March 2025. These grants are open to ECRs that otherwise wouldn’t have sufficient funding to attend a microscopy or bioimage analysis course to support their research in cell biology. www.biologists.com/grants/jcs-f...

An oldie (10 y!) but goodie: cellular interaction at the top! #cellcomm Video of a T cell (orange) interacting with a target cell (blue) From Chen et al. @ Betzig lab (@hhmijanelia.bsky.social) game changing paper !! Full science.org/doi/10.1126/... @focalplane.bsky.social #scicomm #microscopy πŸ§ͺπŸ”¬

#CellMigration for #FluorescenceFriday πŸ§ͺπŸ”¬ If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes... OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide. More in the paper: www.nature.com/articles/s41...

Hot from the press for #CellMigration + #Nucleus aficionados Karling @helenweavers.bsky.social lab show *in vivo* how immune cell adapt quickly to confined microenvironments during motility. Live-cell imaging, image analysis, #Drosophila ! Full @emboreports.org www.embopress.org/doi/full/10....

#CellMigration happens all the time in our bodies. This may (or not) rely on adhesion molecules #Cancer cells switch strategies during metastasis to invade other tissues Naomi Wee (naomiwee.com) did this neat movie to explain it: www.youtube.com/watch?v=D9aD... #SciSky πŸ§ͺπŸ”¬ @cellcommlab.bsky.social

🚨Postdoc vacancy alert! Interested to work on apoptosis/inflammation? Have some experience in biosensor-imaging and quantitative analysis of dynamic systems? 2 positions available for 2 years with potential of extension Apply now! πŸ‘‰ uq.wd3.myworkdayjobs.com/uqcareers/jo...

The #nucleus contains the info of a #cell, but it does much more than that !! Since the nucleus is *big*, acts as the main intracellular obstacle, and during #CellMigration can get 'trapped'/stuck until the cell pushes it FWD. #scicomm @focalplane.bsky.social @cellcommlab.bsky.social #Skyscience

We just released and uploaded a new version of *Mastodon*, the large-scale tracking and track-editing framework for large, multi-view images. Mastodon is available via Fiji, via a dedicated update site. mastodon.readthedocs.io/en/latest/do... Below is a thread that survey some of the novelties ⏬️

The Institute for Integrative Biology of the Cell (I2BC) is recruiting group leaders in cell biology. Don't miss the opportunity to start your team in the vibrant environment of Paris-Saclay University. Application deadline: Feb 28, 2025 www.i2bc.paris-saclay.fr @i2bcparissaclay.bsky.social

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