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radaiglesiaslab.bsky.social
Enhancer biology in development and congenital disease. Mushrooming and Birding.
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📣 New pre-print from the lab: 👉 “Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML #GBM 📝 Read the #BioRxiv here: doi.org/10.1101/2025...

If you are attending #EMBLChromatin, go and check @mariamafau.bsky.social poster and learn more about how ZIC2 controls neural induction and patterning by playing a dual and sequential regulatory role.

#EMBLChromatin keeps being awesome: fantastic talks, lots of networking and troubleshooting! But guess who is also multitasking? ZIC2! Particularly during neural induction! Come by this afternoon to check poster 158 and I’ll tell you all about it 😉 @radaiglesiaslab.bsky.social

I am thrilled to share our preprint where we take advantage of the unique opportunities offered by human blastoids to uncover a human-specific mechanism potentially playing a role in preimplantation 🧵. www.biorxiv.org/content/10.1...

Very happy to share the peer-reviewed version of our paper in which we study the formation and function of pair-wise and multi-way enhancer-promoter interactions in gene regulation (see thread below): www.nature.com/articles/s41...

Check out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social. www.nature.com/articles/s41... This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu

Please RT ! Gordon Conference “Histone and RNA modifications” Tuscany 🇮🇹 20.-25. July 25 🗓️ Theme: Regulation of genome function by histone and nucleic acid modifications. Great speaker lineup. >20 talks will be chosen from abstracts. Submit yours soon ➡️ shorturl.at/hBjyT

Our BAT paper is accepted in Nature Ecology & Evolution! Single cell, gene regulation, TADs and key TFs that shape the bat wing. Genomics goes Evodevo 😍

Really proud of Michaela Bartusel, who initiated this work while being a PhD in our lab. Michaela never gave up and, together with the great guidance of my friend and former colleague Eliezer Calo, made some very interesting findings regarding the genetic basis of orofacial clefting.

Celebrating 10 years of our lab with a new preprint: www.biorxiv.org/content/10.1... How does enhancer location within a TAD control transcriptional bursts from a cognate promoter? Experiments by Jana Tünnermann and modelling by Gregory Roth

Te quedan tres días (solo hasta el lunes 31 de marzo) para hacerte con algún ejemplar de los pocos que quedan de dos de mis libros editados por #NextDoor #EditandoGenes sobre #CRISPR y #PorQueMiHijo sobre #enfermedadesraras Los tienes disponibles en: www.nextdoorpublishers.com/libros/

This is a super-interesting, though speculative, paper from Adrian Bird. He is challenging the prevailing view that the protein cohesin organizes chromatin for functionality (transcription) by creating loops that allow genes to access their regulatory regions... www.cell.com/molecular-ce...

📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪

Postdoc position #1 is live! Please apply / spread the word! lms.mrc.ac.uk/work/vacanci...

📣 Four more days left to submit your abstract to the @embo.org workshop on "Enhancer mechanics and Enhanceropathies". Submit now and present your latest work in one of our short talks 📣 #EMBOenhanceropathies 👇

Only one week left to submit your abstract to the @embo.org workshop on "Enhancer mechanics and Enhanceropathies". Submit now and present your latest work in one of our short talks.

Don't miss the opportunity to present your work at this exciting @embo.org workshop on enhancer mechanics! 🧬 Submit an abstract latest by March 17 to be considered for a short talk 🔊, and by April 1 to present a poster. ✏️ Please share!😀 #genomics, #transcription, #chromatin

This was an awesome meeting last time out- #enhancer folks should register now!

Do you have an exciting story about #enhancers or #enhanceropathies?. Then submit your abstract to the @embo.org workshop on "Enhancer mechanics and Enhanceropathies" in Denmark before is too late: the deadline for abstract submissions is in two weeks (March 17th)! meetings.embo.org/event/25-enh...

#Enhancer folks, submit your abstracts and register soon! Deadlines are around the corner and there are many opportunities for short talks.

Important paper showing that acetylation of trans-acting factors rather than histones controls transcriptional bursting dynamics www.cell.com/molecular-ce...

!THREE OPPORTUNITIES TO JOIN US! We are looking for 3 (!!!) PhD students interested in: How Metabolism affects Genome Regulation. Join us at @carrerasijc.bsky.social as Marie Sklodowska Curie network fellow. More info: 2 x experimental: www.nuclear-dn.eu 1 x computational: www.hubmol.eu

Looking forward to it!! Abstract submission deadline: 17 March 2025.

Excited to announce that the EMBO workshop on Enhancer Mechanics and Enhanceropathies, June 16-20, 2025, Hindsgavl Castle, Middelfart, Denmark, is now open for registration and abstract submission. !! SAVE THE DATE and register soon !! 👇 meetings.embo.org/event/25-enh... #EMBO #enhancer

2025 EMBO workshop on "Enhancer Mechanics and Enhanceropathies" now open for registration I was at the 2023 workshop in Marseille and it was a great event - recommend!

Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21). Book the dates and register soon!!! meetings.embo.org/event/25-enh...

New paper out at the Journal of Neuroscience from our president’s @eloisaherrera.bsky.social lab!👇🏻👇🏻👇🏻

Fantastic opportunity: 🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH 👉 go.epfl.ch/ELISIR

📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy

Birding in Santoña

Fulfilling a family tradition the day before Christmas. Hike to la Picota #Cantabria

Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!

Congrats, Ana Pombo! The #mdcBerlin scientist receives Germany's most important science prize: the Gottfried Wilhelm Leibniz Prize by the German Research Foundation #DFG. About @apombo1.bsky.social and her work: www.mdc-berlin.de/news/news/an... #mdcBIMSB @www.helmholtz.de @humboldtuni.bsky.social

I wrote some thoughts about why peer review matters It shapes scientific standards, maintains field coherence & trains new researchers Yes, it needs improvement—but it's the glue that holds scientific progress together briscoelab.org/2024/12/11/i...

I am happy to share our latest accepted article @dev-journal.bsky.social The work of Carolyn Engel-Pizcueta in col with Jean Livet at Institut de la Vision (Paris). Enjoy the reading !! journals.biologists.com/dev/article/... @sebioldev.bsky.social

We are live on Bluesky too!