reptilerhett.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Get more from your sequencing. #PacBio HiFi reads are long, accurate, and packed with insights—from variant detection to methylation—all in a single workflow. 🎥 Watch the video to see what makes it different: bit.ly/4msXbWJ #PrecisionWithHiFI #HiFisequencing

submitted 16 hours ago • 0 comments

Friendly reminder: #PacBio wants to hear from you! Take our survey by Friday for a chance to win: 🎁 A complete, free Revio SPRQ sequencing run 💳 $1,000 PacBio coupon 🎉 $100 Amazon gift card (or equivalent) Take the survey: bit.ly/4cjoopZ Official rules are at the end of the survey.

submitted 2 days ago • 0 comments

That’s a wrap on #PacBioPRISM 2025 in Boston! Over two days, we welcomed 220+ attendees for impactful talks and great conversations. It was the perfect way to close out this year’s #PacBio PRISM series. Thanks to everyone who joined us — we’re excited for what’s ahead.

submitted 3 days ago • 0 comments

So fantastic to see an all women panel at #PacBioPRISM today moderated by @magdoll.bsky.social. #HiFi #longreads @pacbio.bsky.social

submitted 7 days ago • 0 comments

Day 2 of #PacBioPRISM 2025 in Boston was a huge success! Inspiring talks on rare disease, cancer genomics, and more showed how HiFi sequencing powers discoveries across science and medicine. So grateful to be part of this innovative community. One more day to go! #PacBio

submitted 6 days ago • 0 comments

Awesome talk today by Adam Healey from Hudson Alpha on tackling the sugarcane genome with @pacbio.bsky.social #HiFi #longreads.

submitted 7 days ago • 0 comments

Great talk today by @treangen.bsky.social from Rice University on the advantages of @pacbio.bsky.social #longread #hifi for #microbiome and #metagenomics research + assembly of the great horned owl.

submitted 7 days ago • 1 comment

This week's HiFi fun fact: the #PacBio HiFi Solves consortium is a global dream team of clinical researchers. 🌍 Can you guess how many institutions are repping this HiFi-powered squad? Whatever the region. Whatever the research. #ThereHiFiForThat

submitted 7 days ago • 0 comments

From rare disease to reference-grade ape genomes, April’s Powered by #PacBio blog features studies in human health, evolution, agriculture & cancer—powered by #HiFiSequencing. See what researchers are uncovering with long-read data: bit.ly/3H3JxJb

submitted 10 days ago • 0 comments

Just wrapped #PacBioPRISM 2025 in San Francisco! 🌟 Grateful to connect with passionate scientists, innovators, and thought leaders pushing the boundaries of genomics with #PacBio. Thanks to all who made it unforgettable—next up: Boston!

submitted 13 days ago • 0 comments

Had a great time at #PacBioPRISM chatting to the community about the utility of reference genomes and the potential of long-read sequencing in conservation 🦊🐆🐺🐻 ! Some very inspirational talks and lots of potential applications to think about in the future!

submitted 14 days ago • 1 comment

🌟 Day 2 of #PacBioPRISM 2025 in San Francisco showcased groundbreaking research — from rare diseases and cancer to plant and animal genomics. Interactive workshops and networking sessions made it even more impactful. Proud to be part of a community driving innovation in science! #PacBio

submitted 14 days ago • 0 comments

Celebrating 25 years of big questions—like: What if researchers could actually see it all? We're kicking off a trivia series featuring rare disease wins, breakthroughs & proof that whatever the challenge, #TheresHiFiForThat. Which method uncovered 93% of the variants short reads missed? #PacBio

submitted 14 days ago • 0 comments

Join #PacBio at #ESHG2025 to explore scalable solutions for human disease research—from PureTarget panels to Kinnex RNA discoveries. 📍 Join us in Milan, 24–27 May. 📄 View the full agenda: bit.ly/3GG9wX7 The future of sequencing starts with HiFi...

submitted 15 days ago • 0 comments

@pacbio.bsky.social instrument lounge at PRISM San Francisco event today! Great talks this morning and now we’re moving into parallel workshops.

submitted 15 days ago • 0 comments

After stops in Danang and Athens, the #PacBioPRISM global tour has arrived in San Francisco! 🇺🇸 We kicked off Day 1 with 25 years of #PacBio innovation and a powerful keynote from Sean Baumstark on resilience, purpose & living beyond limits. We’re just getting started!

submitted 15 days ago • 0 comments

Emily Farrow from Children’s Mercy Hospital is the first speaker on day 2 of @pacbio.bsky.social PRISM SF.

submitted 15 days ago • 2 comments

Berry Genomics is transforming single-gene disorder testing in China with #HiFisequencing. Their Thalassemia assay has boosted diagnosis rates and is now powered by the #Vega system. Read the full story: bit.ly/4iOussj #PacBio #ClinicalGenomics

submitted 15 days ago • 0 comments

It was great to attend PacBio Prism in Athens & hear from leading experts about the latest developments in LRS and how they are applying these technologies to bring real answers to patients especially in rare & complex diseases. 🇬🇷🧬✨ @pacbio.bsky.social @uclqsion.bsky.social

submitted 17 days ago • 0 comments

#PacBio and Chulalongkorn University announced a newborn screening research program using HiFi WGS in Thailand—the first in Asia Pacific at population scale. The study aims to show how genome-wide data can improve early detection of rare, treatable conditions. Details here: bit.ly/4jD0TuV

submitted 17 days ago • 0 comments

About NSF’s new(est) bulletin - 15% indirect cost rates will kill universities. Apparently that’s the point. I am sick.

submitted 21 days ago • 3 comments

Close to home. Go Miami!

submitted 20 days ago • 0 comments

#PacBioPRISM 2025 in Athens is a wrap — and what an unforgettable few days it’s been! Thank you to everyone who joined us. Together, we’re shaping the future of genomics. Congratulations again to our award winners—celebrating this community is always a true highlight. #PacBio

submitted 20 days ago • 0 comments

We’re proud to announce the PacBio Compatible partners sponsoring #PacBioPRISM 2025 in San Francisco and Boston. If you’re attending, don’t miss the chance to connect with these industry leaders onsite and explore how their technologies support and enhance #PacBio sequencing.

submitted 21 days ago • 0 comments

Thanks to everyone who stopped by the #PacBio booth at #AACR25! It was a great week of conversations around cancer research, long-read sequencing, and what’s next for HiFi. We’re proud to be part of the progress.

submitted 21 days ago • 0 comments

And really nice press release by @reginafairbanks.bsky.social www.amnat.org/an/newpapers...

submitted 22 days ago • 0 comments

Have you heard the news? @pacbio.bsky.social is expanding their methylation detection capabilities. Look at epigenome variation alongside your HiFi reads with no additional prep necessary!! Also…if you haven’t heard of Fiber-Seq…look it up. Forget about ATAC-Seq and start Fiber-Seq(ing).

submitted 24 days ago • 0 comments

192 years old—and still going strong. 🐢 What secrets lie in the DNA of the world’s oldest land animal? This #EarthDay, discover how sequencing Jonathan the tortoise is helping unlock the science of longevity. 🌍 Curious what makes Jonathan timeless? Read the preprint: bit.ly/4iikQWn

submitted 30 days ago • 0 comments

Excited to announce the winners of the 2024 SMRT Conserve Grant! 🌍🔬 This year’s grant supports endangered vertebrate species research with #PacBio HiFi sequencing + Hi-C. Thanks to all who applied—we're proud to back such vital conservation work. Meet the winners: bit.ly/41QrBIQ

submitted 70 days ago • 0 comments

I didn't know PacBio maintained its own curation of sample/reference datasets. Saves me a bit of trouble of hunting down reliable ones for a pipeline testing: www.pacb.com/connect/data...

submitted 85 days ago • 0 comments

NEW: HiFi now brings Hi-C to #HiFisequencing with CiFi. Traditional short-read Hi-C falls short in repetitive and low-complexity regions, but #PacBio HiFi delivers with superior accuracy and lower input needs. bit.ly/4b8k10m #AGBT #AGBTGM

submitted 90 days ago • 0 comments

This looks extremely promising and it works with smallish amounts of input DNA. Why? Because it applies long range PCR amplification with 'polC' (KOD Xtreme™ Hot Start DNA polymerase) that we investigated in depth here: genomebiology.biomedcentral.com/articles/10.... #PacBio #HiFiSequencing #PCR

submitted 88 days ago • 0 comments

In honor of #RareDiseaseDay this month, learn how #PacBio HiFi sequencing is transforming the #RareDisease landscape for researchers like @childrensmercy.org. Blog here: bit.ly/3XbaMa7

submitted 91 days ago • 0 comments

Are you attending #AGBTGM? EpiCypher will be there, and we have some exciting chromatin mapping tech to share! How to find us: 🧬 DNA Methylation & Multiomics: Poster 447 on 2/24, 1:30-2:30PM 🧬 Long Read Seq: Poster 404 on 2/25, 4:45-6:10PM 🧬 DM if you want to set up a meeting!

submitted 91 days ago • 0 comments

We’ve passed 260,000 strike cards! We understand that people are tentative about signing their strike card. Here’s some info to help with that. drive.proton.me/urls/HZR5333... bsky.app/profile/gene... beautifultrouble.org/toolbox/tool...

submitted 92 days ago • 8 comments

I ❤️ Jonathan! Think of the things Jonathan has lived through. Fun fact: 192 years ago in 1833. The first enzyme was discovered and such was dawn of biochemistry….now we are out here sequencing Jonathan’s whole genome and methylome…

submitted 100 days ago • 0 comments

🧬🧪 Breaking news - EpiCypher will be developing Fiber-seq enzymes, kits, and services! First off- what is Fiber-seq? Fiber-seq is a method developed by the Stergachis lab, that allows users to map chromatin accessibility on long-read sequencing platforms. (1/n) www.genomeweb.com/sequencing/l...

submitted 105 days ago • 2 comments

Hi-C users, the wait is finally over! 🙌🏽 CiFi now enables Hi-C with #HiFisequencing. Short-read Hi-C struggles when it comes to repetitive and low-complexity regions. #PacBio HiFi rises to the challenge with better accuracy and lower input requirements. Congrats Megan and UC Davis team!

submitted 105 days ago • 0 comments

The 200k signatures goal has now been met and exceeded! 💪 Protests are a great time to build trust & community within all of our coalitions. Get out there if you can, share what you know with someone new, and trade web & social contacts!

submitted 106 days ago • 6 comments

"As #longread sequencing is more often used in #microbiome studies, we anticipate that our findings will open new dimensions to characterize how gut bacteria adapt to various stress conditions and host interactions using #epigenetic mechanisms." #PacBio 🧵 1/5 www.biorxiv.org/content/10.1...

submitted 106 days ago • 1 comment

Hi-C and HiFi…the perfect combination! Very excited for @mydennis.bsky.social to introduce the world to CiFi. Well done! I know a lot of people have been looking forward to this! @pacbio.bsky.social

submitted 106 days ago • 2 comments

“V3-V4 #16S rRNA sequencing was sufficient for genus-level analysis. However, V3-V4 sequencing was shown to perform poorly at the species-level, this study demonstrates using full rRNA operon (16S-ITS-23S) sequencing performs much better at this level.” #PacBio 🧵 1/3 www.nature.com/articles/s41...

submitted 118 days ago • 1 comment

With the new #PacBio Ampli-Fi protocol, you can now sequence genomes with as little as 1 ng of DNA! Paired with our #HiFisequencing technology, it provides a powerful solution for assembling high-quality genomes with exceptional accuracy. #PAG32

submitted 129 days ago • 0 comments