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rkoszul.bsky.social
#3Dgenome, #3R, #chromatin, #synbio, #microbiome... Opinions are my own.
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How to find Evolutionary Conserved Enhancers in 2025? 🐣-🐭 Check out our paper - fresh off the press!!! We find widespread functional conservation of enhancers in absence of sequence homology Including: a bioinformatic tool to map sequence-diverged enhancers! rdcu.be/enVDN github.com/tobiaszehnde...

Excited our paper is out in Cell @cp-cell.bsky.social! 🧬⚡ DNA photo-crosslinking proteomics in living cells 🎯 Pinpoints protein-DNA interactions to single amino acids 🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes 🔗 www.cell.com/cell/fulltex... 🧵

#CoNRS #CNRS #ESR La liste des candidat.e.s par section est maintenant disponible Vote du 19 au 26 juin 2025 www.dgdr.cnrs.fr/elections/sc...

I will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!

New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!

Come start your lab in beautiful Strasbourg 🇫🇷 www.nature.com/naturecareer...

So after 2 months of trump2 you now need a burner phone to enter the US 😭

Neonatal fungi promote lifelong metabolic health through macrophage-dependent β cell development | Science www.science.org/doi/10.1126/...

Suite à la conférence de presse entre D. Trump et V. Zelensky vendredi dernier, qui a basculé avec la mention de négociations avec la Russie sur l'Ukraine, #LeCollimateur se penche sur l'histoire et les perspectives de négociations avec V. Poutine, avec Dimitri Minic. ▶️ lerubicon.org/collimateur-...

Once upon a time, in the late 1800s, people in Japan got really into breeding mice. Coloured mice. Patterned mice. Even mice that danced. They became known as Japanese Fancy Mice, and that caught the attention of researchers in Europe and America, who imported them for study. 2/n

Job alert: full-time researcher position for AI with CNRS here in France. Initial contract for 5 years (tenure track). Attractive starting package and better salary than regular positions. I have been w/ @cnrs.fr since 2013, it's great! Applications due 31/03 www.ins2i.cnrs.fr/en/cnrsinfo/...

Are you curious about eukaryotic plasmids? PhD student Fabien Girard with Axel Cournac in the lab explore the positioning of plasmid 2u, one of these rare (known) episomes, in the budding yeast nucleus. The results were surprising. #plasmids #chromatin #3Dgenome www.embopress.org/doi/full/10....

Zelensky is a wartime leader watching his people suffer and die under Russian attacks every day. To be lectured and lied to by Trump and Vance, as they defend the war criminal dictator committing these atrocities, is unimaginable agony. An everlasting shame for America.

"officials at the Dept. of HHS... have pressed staff at the agency to ignore court orders, according to nearly a dozen former and current NIH officials I spoke with. Even advice from NIH lawyers to resume business as usual was dismissed by the agency’s acting director, those officials said."

One week left!! Here is a reminder that Institut Pasteur launched an International call to recruit top young researchers. Diversity, Equity, Inclusion, and improving health for people worldwide are among our top priorities. Come join our international community of passionnate and driven scientists.

Our new review on how the #chromatin domain is formed in the cell is now available @Curr Opin Struct Biol.📄✨ We critically discuss the domain formation mechanism from a physical perspective, including #phase-separation and #condensation. 📥 Free-download link: authors.elsevier.com/a/1keGn,LqAr...

If it hasn't sunk in: The United States is aligned with Russia in a war of aggression against Ukraine and the broader democratic world.

AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns Today, @arcinstitute.org in collaboration with Nvidia releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life.

I have to admit I never thought I'd see the day when a US vice president would warmly support European far right and spit on all democratic principles. www.theguardian.com/us-news/2025...

🤨 SCotUS in ‘Grants Pass v. Johnson’ makes the EXACT SAME ARGUMENT on criminalizing homelessness that was used as a joke by Anatole France: “The law, in its majestic equality, forbids the rich and poor alike to sleep under bridges, to beg in the streets, and to steal bread.”

Two more weeks to apply to join us in Paris ! research.pasteur.fr/en/call/call...

Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin? By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient! #chromatin #3Dgenome #generegulation www.science.org/doi/10.1126/... 👇

This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/... #microsky #microbial #microbiology #genomics #transcriptomic 🦠🧫

If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)