rogerjlewis.bsky.social
Emergency physician and statistician; Bayesian adaptive and platform trial clinical trial design and implementation; Senior Statistical Editor at JAMA.
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I love how well this point is made, though I don't think the marketplace of ideas should be neutral but, rather, should preferentially value those supported by actual objective evidence.
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Guidance outlining key design points and specific reporting requirements was published earlier this year 7/7
www.bmj.com/content/388/...
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When they are applied appropriately, however, they can be effective. Examples include the SUDDICU and the PEPTIC trials 6/7
SUDDICU: jamanetwork.com/journals/jam...
PEPTIC: jamanetwork.com/journals/jam...