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souvik-uthealth.bsky.social
Assistant Professor @University of Texas Health Science Center at Houston; #NewPI Bacterial behavior, Antibiotics, Bacterial Memory, Necrosignal; GGMU, Chess, Photography; ⚽ ♟️ 📷 he/him www.souvikbhattacharyyalab.org
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Prolific Poster

(Longish thread. Apologies) I have met many inspiring colleagues over the past few months, many of whom are in academic institutions targeted by the current administration, and many others who are about to be (the analogy to the ‘eye of Sauron’ has been invoked many times; gallows humor). 1/

Sharing the most significant work from my group, led by the @evolvingstem.bsky.social team. Come for the discoveries of how Pseudomonas adapts in biofilms, stay for the story of how they were discovered by thousands of young scientists in grades 9-12. 🧪🧫🧬🧵 www.biorxiv.org/content/10.1...

NEW: Unbelievable. A seemingly endless line of tanks & other military vehicles arrive in DC ahead of next week's parade. They departed Texas 5 days ago. What a colossal waste of time, money & military resources. All for a President who has shown zero respect for service personnel. (🎥 DW)

This parade will cost at least the equivalent of 180 years worth of an NIH biomedical research grant.

Our study on the first probiotic treatments for SCTLD testing in the wild has been published! www.sciencenews.org/article/prob...

🚬The molecular impact of cigarette smoking resembles aging across tissues ⭕This is the 1st comprehensive, multi-tissue analysis to show that smoking doesn’t just harm specific organs like the lungs 🫁 📄By BSC & Universidade do Porto researchers, published in Genome Medicine: bsc.es/Zt2

How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.

Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/... Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺

Major update to #SCIMaP visualization of impacts of cuts to federally supported health research. Map now includes information on future economic losses (impact of proposed reduction of NIH IDC to 15%) and current economic losses (impact of terminated NIH grants). scienceimpacts.org

Exciting news!! Our latest paper is out in Nat. Microbiol. @natmicrobiol.nature.com We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3 www.nature.com/articles/s41...

🚨 Out now! West African South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems #MicroSky 🦠 #Phage @mblokesch.bsky.social www.nature.com/articles/s41...

Napoli...What a story!

The May issue of JB is out! MInireviews on mobile elements i, M. marinum as a model system, gut microbiota & obesity, colony morphologies in Burkholderia, plus iron and energy metabolism. I'll highlight research papers in the coming weeks! journals.asm.org/toc/jb/207/5 @asm.org #JBacteriology

That was fast. @nbcnews.com www.nbcnews.com/politics/imm...

"Even when explicitly prompted for accuracy, most LLMs produced broader generalizations of scientific results than those in the original texts."

I need every single journalist covering vaccine stuff at the FDA to be explicit about this. Thank you @katherinejwu.com. www.theatlantic.com/health/archi... There is a genuine open question regarding the degree of benefit for otherwise healthy kids to get seasonal COVID-19 boosters.

Testifying tomorrow at a Senate hearing showcasing damage done to HHS by (personnel) terminations 3:00-4:30 convened by Senators Welch and Baldwin. With former leaders from CDC, SAMSHA< AHRQ, ACL (Admin. for Community Living) www.cbsnews.com/news/rfk-jr-...

It's not just Northwestern and Harvard, I have gotten credible (confidential) reports from several other schools (including state schools) that the NIH is defaulting on federal commitments there too. Seems like there may be a big story here for an investigative reporter willing to take it on

This was just posted by @tbretc.bsky.social on another platform. The Chicago Sun-Times obviously gets ChatGPT to write a ‘summer reads’ feature almost entirely made up of real authors but completely fake books. What are we coming to?

It's official: the #PandemicAccord is officially adopted by the World Health Assembly! My warmest congratulations to @who.int Member States for their commitment to keeping their people and the world safer. What a moment in global health history. Together!

NEW: Dozens of staffers walked out of Jay Bhattacharya’s first town hall event on Monday after the NIH director said he believed the lab leak conspiracy theory. We got video. www.importantcontext.news/p/i-believe-...

Presenting RABiTPy, a Python package for bacterial tracking that works in a jupyter notebook format for: video/image stack import and processing, AI-based or traditional cell segmentation, cell tracking, trajectory analysis, and downstream plotting bmcbioinformatics.biomedcentral.com/articles/10....

If people of means are interested in establishing a 2025 “Institute for Advanced Study” for displaced/defunded biomedical scientists, I know many people who will help, including myself. @mcuban.bsky.social @arcadiascience.com @arcinstitute.org

Thank you so much to @drlauranolan.bsky.social and Mark Webber for putting this JBC review together. Such exciting days that bacterial genetics and transposon mutagenesis can push the boundaries on discovering novel gene function and put more light on the genomic dark matter. See at rb.gy/ovefri

Not good: www.usatoday.com/story/money/...

www.science.org/doi/10.1126/...

To be clear, if this bill passes, it will end all scientific research & medical training in the US. It will close hospitals. It will be economically devastating. Millions will lose their jobs. Call your representatives & tell them to vote fuck no on 15% IDC rates & the rest of this horror show.

A federal judge on Friday indefinitely prohibited the Department of Health and Human Services from terminating $11 billion in public health grants set aside for states.

How horrible

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

For our first post on Bluesky, we're excited to share our recent work published in mBio @asm.org! Led by PhD student @madeofmicrobes.bsky.social, we show that flagellar motility and interactions with the mucus environment influence Pseudomonas antibiotic tolerance. journals.asm.org/doi/10.1128/...

New report from Bernie Sanders, ranking member on the HELP committee www.sanders.senate.gov/wp-content/u... Lots of substance in here. Some highlights... 1/n

"The force that propelled the US was the visionary decision by the government to become a massive funder of basic science. . . Universities competed for research funds. The federal government wrote the checks but did not try to run the programs."

Definitely worth the 5 minutes to watch. Succinct summation of what is being thrown away

important historical perspective on the value of federal funding of basic research at universities: "These are the building blocks of America's extraordinary strength, created over the last 100 years, and they are now being dismantled in 100 days" 🧪 www.youtube.com/watch?v=0Qk4...

Microbiology Monday: To swim or to swarm? 🦠While c-di-GMP inhibits swimming to promote biofilm formation in E. coli, elevated levels of the secondary message molecule trigger production of a surfactant (colanic acid) that aids swarming. #mBio: asm.social/2pm

As a follow-up to the Kaiser interview, here is my exchange with Dr. Bhattacharya starting Sunday evening... 1/n

Wow www.biorxiv.org/content/10.1... A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome

And that, my friends, is a sign that congressional Republicans in purple states and districts are rightfully starting to panic.

This large multi-center study shows cancer patients are infected with #AMR bacteria at 1.2 to 3 times higher rates due to frequent hospital visits and antibiotic use. This highlights the need for better antibiotic #stewardship and surveillance in these patients. www.thelancet.com/journals/lan...

This is about all of us. Never forget that.

I am extremely pleased to share this feature articulating why I have lost my sanity lately. www.science.org/content/arti...

On similar veins, I tried to complete Sapiens by Harari but was super disappointed by multiple evolutionary inaccuracies and overtly simplistic'storytelling'.