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The FDA approved twice-yearly lenacapavir (Yeztugo) for PrEP, making it the longest-acting HIV prevention method. Advocates lauded the eagerly awaited approval but expressed concern that the $28,000 annual price tag could limit access as HIV prevention funding is being slashed in the US & worldwide.

submitted 5 hours ago • 4 comments

New transparency policy at Nature: "all new submissions to Nature that are published will be accompanied by referees’ reports and author responses -- to illuminate the process of producing rigorous science." www.nature.com/articles/d41...

submitted 5 hours ago • 0 comments

New Trump ousters of Nicole Verdun and Rachael Anatol are a 'significant setback' for potential disease cures through gene therapy www.rawstory.com/gene-therapy/

submitted 4 hours ago • 0 comments

Vinay Prasad was named as both the FDA’s chief scientific officer and chief medical officer TODAY. He immediately fired Nicole Verdun, who was in charge of cell and gene therapies. “Now, there will definitely be concerns and questions about what this means for the division under Vinay Prasad”.

submitted 5 hours ago • 32 comments

One of the most spectacular tricks that the “wellness” grift has managed to pull off is convincing people that their industry is untainted by money. That they are all doing it out of their deep concern for their customers’ health. Yet the global supplement industry alone is worth $177 billion.

submitted 6 hours ago • 83 comments

JNJ-6640: First-in-class PurF inhibitor demonstrates nanomolar bactericidal activity against M. tuberculosis. Targets de novo purine biosynthesis pathway, showing in vivo efficacy in mouse models. Nature: www.nature.com/articles/s41...

submitted 6 hours ago • 0 comments

🧵: Gilead's greed & Trump's attacks on the HIV response imperil global access to #lenacapavir, a breakthrough prevention tool approved today. Me in www.nytimes.com/2025/06/18/h..., & our reaction w/@hji-sa.bsky.social, @justtreatment.org, Sankalp Rehabilitation, ABIA: healthgap.org/press/gilead...

submitted 7 hours ago • 1 comment

vinay prasad stamping out dissent

submitted 6 hours ago • 0 comments

www.theguardian.com/society/2025...

submitted 9 hours ago • 0 comments

Bhattacharya is evil or incompetent. Probably both. NIH Director Jay Bhattacharya has pushed "back on concerns raised by his own staff that the ouster of essential employees and other disruptions to the biomedical research agency were harming science and patients." #GiftLink 🎁

submitted 9 hours ago • 2 comments

Not enough people know this man. His name. His face. His mission. He is a one-man wrecking ball. He's a radical. And he's in charge. www.politico.com/news/2025/06...

submitted 8 hours ago • 3 comments

SCOTUS just let states block gender-affirming care for trans youth. A devastating decision especially given that gender affirming care is life-affirming and life-saving. Support trans-led orgs that are providing material and other support to trans youth and their families.

submitted 9 hours ago • 0 comments

There’s a risk that #LEN for #PrEP becomes another squandered opportunity. “But [we could] get this half right with #lenacapavir, & we build the platform to move to 1x yr lenacapavir + a monthly oral tablet by 2028 & we begin to see a decline in incidence. It’s a decision for the world to make."

submitted 10 hours ago • 0 comments

Given the challenging last few months, this is a bright spot - the approval of lenacapavir twice yearly to prevent HIV. Unlike past PrEP meds, it was found t be 100% protective in cisgender women. But it will only work if gets to people, especially those communities that need it most.

submitted 10 hours ago • 2 comments

Really grateful @cidrap.bsky.social covered our volunteer project reviewing vaccine RCTs. We're up to 335 trials with >5.8 M participants and counting. "Essentially every childhood vaccine has been tested in placebo-controlled trials of some sort." cidrap.umn.edu/adult-non-fl...

submitted 10 hours ago • 1 comment

“Kennedy’s actions have no basis in science or medicine. He brays that Americans don’t trust public health or vaccines, but to the extent that this is true, it is a direct result of his own promotion of anti-vaccine misinformation…”. This OpEd from me and @jimalwine.bsky.social is now online.

submitted 10 hours ago • 38 comments

The @fda.gov’s approval of lenacapavir for HIV prevention marks a major step forward. This long-acting injectable could revolutionize protection for people at highest risk. But approval is just the beginning. Now we must ensure access. Learn more: unitaid.org/news-blog/un...

submitted 10 hours ago • 0 comments

This is so scary it’s hard to think about…but I have to. “Some people believe that the term anti-vaxxer is a pejorative,” the physician Robert Malone wrote on June 9. “I do not — I view it as high praise.” …Two days later, he was appointed to the advisory board that steers America’s vaccine policy.”

submitted 10 hours ago • 0 comments

“It’s hard to overstate the importance of this for global public health,” O’Day said, adding that the injection “really will bend the arc of the epidemic as we roll this out across the globe.” But the magnitude of its impact will also depend on how easy it is to get"

submitted 10 hours ago • 0 comments

“By deciding that the court has no role in weighing scientific evidence as long as there is some claim of scientific uncertainty, Roberts opens the door for bans on gender-affirming care for adults, as well as bans on other politically contested, but scientifically well-founded, treatments.”

submitted 10 hours ago • 0 comments

One thing I am seeing misreported in the media today about the Skrmetti ruling is a claim that the supreme court ruled this is "about age, not transgender status." SCOTUS also ruled this is about "diagnosis, not transgender status" Bans targeting adults are likely legal under this ruling.

submitted 9 hours ago • 42 comments

Today is a particularly good day to support trans mutual aid as a concrete way to fight back against the fuckers trying to take their healthcare and other rights away. 🧵 of a few groups, campaigns, and individuals you can donate to:

submitted 15 hours ago • 4 comments

Well, that was short-lived: NIH staff received instructions to HOLD funds to Columbia again. The email was one line: "Columbia University and Columbia University at Morningside are back on hold."

submitted 11 hours ago • 13 comments

Grants at Columbia unfrozen at 9:30 this morning... Refrozen at 2:30 this afternoon with instructions to undo all of the releases done earlier. It like the 7th graders in detention broke into the Principal's Office...

submitted 11 hours ago • 12 comments

Strategies for shortening #tuberculosis therapy www.nature.com/articles/s41... (open access) @natmed.nature.com

submitted 12 hours ago • 0 comments

today I am thinking a lot about the 2016 bathroom ban and the subsequent uproar and how completely insane it feels to be here, 9 years later. and I think what you have to take away from that is so much responsibility lies with right-wing media, sure - but also with The Atlantic, with the NYTimes,

submitted 14 hours ago • 14 comments

Same in the UK

submitted 12 hours ago • 4 comments

These assaults, handcuffing and detention of elected officials are purposeful. They are intended to communicate that no one is safe and we should be silent. The are telling all of us that if we oppose their actions, we should know they're unfettered by the rule of law & feel free to assault anyone.

submitted 15 hours ago • 54 comments

[Proposed] Final Judgment from Judge Young in the NIH grant termination cases 1/n

submitted 13 hours ago • 5 comments

Today in #Skrmetti, SCOTUS allowed Tennessee's cruel ban on necessary care for young trans people to stand—a devastating blow to the most vulnerable in our community. Today is a loss, but we won't stop fighting for full equality. Read our statement at the link in our bio.

submitted 13 hours ago • 2 comments

Again, the single greatest problem (among the many problems of being ruled by 9 Wizards In Robes) with SCOTUS is that its "conservative" members systematically ignore science, history, data, empirical evidence, & statistics. The fascism comes robed in parlor game theories, gut feelings, & anecdotes.

submitted 12 hours ago • 3 comments

Today, the Supreme Court upheld state bans on gender-affirming care. Before the ruling came down, @evanurquhart.bsky.social spoke to trans youth and their parents about why they sought this care, and how this decision could jeopardize their safety. www.teenvogue.com/story/skrmet...

submitted 15 hours ago • 3 comments

This is monstrous and vile. They want people to die. And after today’s SCOTUS ruling, there are likely many trans kids who could use such easy access to the hotline. It’s not as simple as 988, but you can contact The Trevor Project’s crisis support 24/7/365 directly, via chat, phone, or text:

submitted 13 hours ago • 0 comments

Here is the agenda for the June 25-26 meeting of ACIP. Vaccine recommendations that RFK Jr.’s team of unqualified anti-vaxxers will discuss include COVID19, RSV, and influenza. My guess is they will vote to severely restrict recommendations for these vaccines. www.cdc.gov/acip/downloa...

submitted 13 hours ago • 16 comments

The Trump administration is actively trying to kill LGBT teenagers.

submitted 13 hours ago • 0 comments

Here's what everyone needs to know about today's big trans rights ruling: There will be states where trans youth will be able to access lifesaving, medically necessary care, and states where they won't and they and their families will suffer grave harm. If that's not inequality, then nothing is.

submitted 14 hours ago • 8 comments

Sotomayor blows the idea that discrimination against gender dysphoria is not discrimination against transgender status out of the water:

submitted 13 hours ago • 3 comments

Today's Supreme Court ruling comes as anti-trans hatred has become inescapable for many families, even in liberal states. These families say they are in survival mode, trying to find ways to protect their children from attacks on all sides.

submitted 14 hours ago • 25 comments

grim [sotomayor, dissent]

submitted 15 hours ago • 1 comment

“Dr. Havers resigned, saying she could no longer continue while the health secretary, Robert F. Kennedy Jr., dismantled the careful processes that help formulate vaccination standards… “If it isn’t stopped, and some of this isn’t reversed, like, immediately, a lot of Americans are going to die”

submitted 13 hours ago • 1 comment

No words. The timing here is unimaginably cruel. It's not just dumping salt on the wound, it's dumping acid on it. The hotline is still available for the next few weeks. We will find ways to keep our community safe, even without the permission of those trying to kill our kids.

submitted 13 hours ago • 2 comments