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tkorem.bsky.social
Microbiome, metagenomics, ML, and reproductive health. All views are mine. So are all your base
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Not getting much attention, except in a recent NYTimes story, is a provision to increase the tax on university endowments and those of other nonprofits.

New paper in Genome Biology! genomebiology.biomedcentral.com/articles/10.... We introduce scale models, a generalization of normalizations that explciitly account for uncertainty in biological system scale (e.g., microbial load).

as a resident of syracuse, ny, a rust belt town that used to be an economic epicenter for the nation: syracuse university is our largest local employer now and if it goes under, so does my town, which has the largest concentration of child poverty in the nation.

"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...

Our paper explaining why Gihawi et al. failed to prove an error in the normalization used by the 2020 cancer #microbiome analysis now out as a Matters Arising in @asm.org #mSystems (w/ @george-austin.bsky.social) 🖥️ 🧬 Thread explaining the key points below. journals.asm.org/doi/10.1128/...

Our paper explaining why Gihawi et al. failed to prove an error in the normalization used by the 2020 cancer #microbiome analysis now out as a Matters Arising in @asm.org #mSystems (w/ @george-austin.bsky.social) 🖥️ 🧬 Thread explaining the key points below. journals.asm.org/doi/10.1128/...

Come and work with me! The Nature Micro team is expanding and we're looking for someone to champion microbial ecology, plant micro & related areas for the journal Knowledge of microbial ecology/plant micro is desirable but we're open to applications from all microbiologists Link below 👇

OUT NOW: Processing-bias correction with DEBIAS-M improves cross-study generalization of microbiome-based prediction models @tkorem.bsky.social & co #microsky #microbiomesky 🧪 www.nature.com/articles/s41...

Happy to share DEBIAS-M, our new method for domain adaptation and bias correction in #microbiome data.🧬🖥️ Microbiome data is very variable, with substantial study- and batch-effects. DEBIAS-M corrects these, enabling robust and generalizable analyses. A quick thread: www.nature.com/articles/s41...

Just let me try and cure cancer for fucks sake.

Whomst among ass profs is not tired of Unprecedented Times? I want a precedent of faculty position straight from PhD and uninterrupted federal science funding for a 50 year career pls.

GET is finally published! - Paper: t.ly/iQct_ (new validations, dry and wet) - Model: t.ly/4jnUI (new tutorial on PBMC 10x Multiome data, and yes you can even fine-tune it on a Macbook) - Analysis package: t.ly/OqLAL - Demo: t.ly/rbFQB - Docker: t.ly/86n_i

Now out "in print": we review domain adaptation methods, along with gaps and considerations for datasets of "biological scale" (many features, few samples, etc.). A fun CIFAR-funded collaboration with @meganakpeters.bsky.social 🧬 🖥️ www.science.org/doi/full/10....

Probably an unpopular opinion, but I’ve seen it advertised recently so a warning: I believe that junior group leader positions are typically a bad career move.

I hope events over the past month demonstrate once and for all that especially in such challenging times men are just too emotionally volatile to be allowed to vote

Thrilled to share our paper on differences in oral microbiome composition across subsistence strategies in Nepal is now out in Microbiome: link.springer.com/article/10.1...

This age of publicly funded and highly valued pursuit of scientific knowledge is an outlying bleep in human history. Could (and the way things are going, would) change before we know it

An absolute game-changer for my / students' grant writing.

It's been a rough year for low-biomass microbiome research - but we've also learned a lot, and the challenges are surmountable. Here, we discuss how proactive study design and careful data analysis can help. 🖥️ 🧬 #microbiome academic.oup.com/jid/advance-...