tylervkent.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

The winner of the SMBE Mid-Career Excellence Award is Amanda Larracuente (University of Rochester). ⭐ 2025 Winners: members.smbe.org/news/Details... 📄 Information on the Faculty Awards: www.smbe.org/faculty-awards

submitted 1 day ago • 1 comment

Schlichta, Peischl & Excoffier reveal how purifying selection on deleterious mutations impacts diversity: while codominant variants create diversity dips, recessive mutations can preserve diversity in bottlenecks through pseudo-overdominance. 🔗 doi.org/10.1093/gbe/evaf107 #genome #evolution

submitted 2 days ago • 0 comments

Very happy (and frankly relieved) to see this paper finally out in peer-reviewed form. (Preprint was posted in August 2021, but this is the world we live in now). rdcu.be/erMk6

submitted 6 days ago • 5 comments

Interested in the evolution of molecular interactions ? We are recruiting a new PhD student with a background in proteomics to study the diversification of the receptor-ligand interaction controlling plant self-incompatibility. --> details here : initiative-excellence.univ-lille.fr/fileadmin/us...

submitted 7 days ago • 0 comments

I am delighted to be starting as an assistant professor in the Department of Molecular Genetics & Microbiology at the University of Florida in January 2026. The lab is broadly interested in the functional, developmental, and evolutionary genetics of cell types and organs across flies and beyond 🪰🧬

submitted 7 days ago • 17 comments

I'm very excited to share the first research paper from my lab! My postdoc Surbhi led this amazing study. We combined genomics, evolution, and biochemistry to explain how telomeres evolved in monkeyflowers. If you're into unusual chromosome evolution please read! @plos.org tinyurl.com/bdeku44x

submitted 9 days ago • 5 comments

We feed you. They hunt us.

submitted 15 days ago • 1252 comments

Diverging Arabidopsis populations quickly accumulate pollen-acting genetic incompatibilities doi.org/10.1093/evle... Now in @evolletters.bsky.social by Christopher Condon et al.

submitted 15 days ago • 0 comments

ACLU: “Trump's deployment of federalized National Guard troops in response to protests is unnecessary, inflammatory, and an abuse of power. By taking this action, the Trump administration is… recklessly undermining our foundational democratic principle that the military should not police civilians"

submitted 18 days ago • 42 comments

A state's Guard has not been federalized like this over the governor's objection since 1965.

submitted 18 days ago • 69 comments

Genome size is surprisingly variable even WITHIN species. Dunja Lamatsch, Martin Haase, Maria Pilcher, and I use flow cytometry to show a nice example of this variation in this new paper, perhaps connected to a resolving whole-genome duplication, in our snails. 💜🐌🧬 doi.org/10.1098/rsos...

submitted 22 days ago • 0 comments

The preliminary program of ProbGen 2026, which will be held at UC Berkeley, is now up: probgen2026.github.io Sharing on behalf of Rasmus Nielsen who is not on this site. For more see his thread on that other site: x.com/ras_nielsen/...

submitted 20 days ago • 0 comments

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...

submitted 20 days ago • 22 comments

Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change

submitted 20 days ago • 2 comments

The mutational dynamics of the Arabidopsis centromeres www.biorxiv.org/content/10.1... Absolutely stunning new preprint on centromere mutation from ‪@labschneeberger.bsky.social‬ @plantevolution.bsky.social ‪@jurriaanton.bsky.social‬ @lisasmith @plantylisasmith.bsky.social‬ & colleagues

submitted 21 days ago • 0 comments

Hi all -- has anyone grown Cardamine hirsuta in their labs? We're starting a project in the lab and wondering if we need to do anything different from standard Arabidopsis/Capsella protocols. Thanks in advance!

submitted 22 days ago • 2 comments

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

submitted 22 days ago • 2 comments

Our lab is moving! I’m thrilled to be joining the Department of Ecology & Evolution at the University of Chicago this fall. I’ll be recruiting PhD students so please spread the word and reach out if interested!

submitted 23 days ago • 5 comments

Check out this brand new fellowship from the Simon’s Foundation in Ecology and Evolution. Incoming grad students this year are eligible to apply. No citizenship restrictions. www.simonsfoundation.org/grant/simons...

submitted 23 days ago • 0 comments

U of T is considering late applications from prospective undergrads for Sept 2025 "to support students who are newly exploring U of T and facing unexpected challenges in their post-secondary education." US student visas being one "unexpected challenge," I imagine future.utoronto.ca/apply/applyi...

submitted 26 days ago • 1 comment

The impact of background selection in mutation-selection-drift balance models of complex trait evolution https://www.biorxiv.org/content/10.1101/2025.05.27.656342v1

submitted 29 days ago • 0 comments

Sally Otto @sarperotto.bsky.social and I are back with the next installment of “Reflections on the history of modeling and theory”, supported by @smtpb.bsky.social. Bob Holt shares his personal history and stories of his life in science: www.youtube.com/watch?v=q8hX...

submitted 29 days ago • 0 comments

In the latest #GENETICS paper, Hannes Becher and Brian Charlesworth describe a new approach for modeling the effects of Hill-Robertson interference on adaptation and variability in non-recombining genomic regions. Read more: buff.ly/vg9uvFE

submitted 34 days ago • 0 comments

#Postdoc Position: Interested in the evolutionary and ecological impacts of whole genome duplication? Join Dr. Tia-Lynn Ashman @drtialynn.bsky.social and I at the U. of Pittsburgh, to test what drives the competitive outcomes between diploids and #polyploids Details: shorturl.at/EHOeJ

submitted 34 days ago • 0 comments

NEW REVIEW! Experimental tests on the evolution of sex and recombination and their adaptive significance Parée and Teotónio doi.org/10.1093/jeb/...

submitted 35 days ago • 0 comments

The recombination landscape of Drosophila melanogaster can be repatterned by a single gene https://www.biorxiv.org/content/10.1101/2025.05.16.654569v1

submitted 35 days ago • 0 comments

Our latest preprint about the effects of rescaling forward-in-time simulations in population genetics - www.biorxiv.org/content/10.1...

submitted 48 days ago • 1 comment

Efficient Estimation of Nucleotide Diversity and Divergence using Depth Information https://www.biorxiv.org/content/10.1101/2025.05.15.654353v1

submitted 37 days ago • 0 comments

I generally dislike this kind of perspective and argument about semantics. But I very much liked this one. My own definition of domestication has been basically this for some time, but the authors lay it out better than I could have, with lots of relevant arguments about the nature of domestication.

submitted 36 days ago • 0 comments

bill kittredge

submitted 37 days ago • 0 comments

When should adaptation arise from a polygenic response versus few large effect changes? https://www.biorxiv.org/content/10.1101/2025.05.15.654234v1

submitted 39 days ago • 0 comments

Truly obscene amount of awesome papers coming out the past few weeks

submitted 41 days ago • 1 comment

Learning the Shape of Evolutionary Landscapes: Geometric Deep Learning Reveals Hidden Structure in Phenotype-to-Fitness Maps https://www.biorxiv.org/content/10.1101/2025.05.07.652616v1

submitted 49 days ago • 0 comments

The landscape of fitness effects of putatively functional noncoding mutations in humans https://www.biorxiv.org/content/10.1101/2025.05.14.654124v1

submitted 42 days ago • 0 comments

The distribution of fitness effects varies phylogenetically across animals https://www.biorxiv.org/content/10.1101/2025.05.13.653358v1

submitted 43 days ago • 0 comments

I'm reviewing applicants later this week and will continue to accept new applications until the position is filled

submitted 42 days ago • 0 comments

happy to see our study on genetic parallelism of reproductive isolation in chickadee hybrid zones out in @evolletters.bsky.social—great work led by Georgy Semenov & Scott Taylor: doi.org/10.1093/evle...

submitted 44 days ago • 1 comment

Two research teams from @cnrs.fr @sbroscoff.bsky.social carried a comparative analysis in flowering plants that supports the prediction that inbreeding, such as self-fertilization, selects for higher recombination rates: doi.org/10.1093/jeb/... Brazier et al. (@romanstet.bsky.social)

submitted 45 days ago • 0 comments

Super excited to share my latest preprint with @klohmueller.bsky.social! Here we leverage the unique signature that recessive deleterious variants can lead to an increase in archaic ancestry to tackle a classic question - the dominance distribution on the human genome www.biorxiv.org/content/10.1...

submitted 48 days ago • 2 comments

Now out in print! Elli Cryan (coadvised by @spicybotrytis.bsky.social) digs deep into the sgtructure and function of hybrid incompatibility loci in maize. Among other things she discovers a conserved, ancient pseudogene haplotype that silences the locus in trans! academic.oup.com/genetics/adv...

submitted 49 days ago • 5 comments

I hope to see you at ProbGen 2026 on March 25th-28th! I expect a wonderful meeting as always!

submitted 49 days ago • 0 comments

In population #GENETICS, Q-ST and F-ST calculations help compare the amount of trait differentiation on one or more traits in genome-wide genetic variants. Using simulations Liu and @docedge.bsky.social, show the effect of various choices made while computing Q-ST. Read more: buff.ly/OwrU9oB

submitted 57 days ago • 0 comments

🧬 Today, we present GSEA winner Dylan Sosa, PhD candidate at the University of Chicago. Dylan investigates the rate, pattern, and mechanisms of transfer RNA gene duplication to understand its propagation and maintenance in D. melanogaster. More on Dylan ⬇️ and follow him: @dylansosa.bsky.social

submitted 55 days ago • 1 comment