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ulrich-lutz.bsky.social
Plant scientist and entrepreneur • Former postdoc @plantevolution.bsky.social • Now building http://biogenda.de and https://custom-lab.de / @custom-lab.bsky.social
19 posts 1,080 followers 836 following
Prolific Poster

Super excited to release a huge evolution project on the works for many years: Evolution experiments synchronized across climates to understand rapid adaptation Preprint: doi.org/10.1101/2025... All data available: www.grene-net.org/data #MOILAB @ucberkeleyofficial.bsky.social @hhmi.org 🧵👇

Sáez-Sandino et al.: A Large Fraction of Soil Microbial Taxa Is Sensitive to Experimental Warming onlinelibrary.wiley.com/doi/10.1111/...

Absolutely thrilled to announce the launch of ARTIC2 - a £5.5M 5 year project funded by @wellcometrust.bsky.social to build on the ARTIC approach of low-cost, globally accessible genome sequencing for surveillance of outbreaks, epidemics and endemic diseases: www.birmingham.ac.uk/news/2025/am...

I generally dislike this kind of perspective and argument about semantics. But I very much liked this one. My own definition of domestication has been basically this for some time, but the authors lay it out better than I could have, with lots of relevant arguments about the nature of domestication.

New Paper out! apsjournals.apsnet.org/doi/epdf/10.... We wanted to know how much genetic variation exists for Zymoseptoria in a single wheat field.

Delighted to share one piece of my postdoc work in preprint: Through forward genetic screening for suberin deposition in root endodermis, we identified SUBER GENE 1 (SBG1) by GWAS as a novel regulator for suberization by interacting with Type One Protein Phosphatase. www.biorxiv.org/content/10.1...

All the materials for the construction of a #DIYNAFLUOR open-source DNA fluorometer have finally arrived and thanks to the excellent build instructions I could complete the assembly in no time. The first test looks great! Thanks so much @willaanderson.bsky.social and team! Fantastic work! 👏👌

It's not too late to register or this afternoon's seminar.....

Now out in print! Elli Cryan (coadvised by @spicybotrytis.bsky.social) digs deep into the sgtructure and function of hybrid incompatibility loci in maize. Among other things she discovers a conserved, ancient pseudogene haplotype that silences the locus in trans! academic.oup.com/genetics/adv...

New CRISPR tools for tomato functional genomics from Eilon Shani! 🍅 🧬 ✂️ www.nature.com/articles/s41...

Amazing study from Jill Anderson, Megan Demarche and colleagues, integrating species distribution models, reciprocal transplants, snow manipulation and more to test whether a montane plant can adapt to climate change. The sad answer: not without human intervention. www.science.org/doi/10.1126/...

„Volkskörper“, „Gesindel“, „entsorgt“, „Genozid“ und „Auslöschung“: Diese Zitate der AfD zeigen das Ausmaß des Rechtsextremismus der Partei. Und das alles ohne den Faschisten Höcke, der eine Nazi-Zitate-Liste ganz alleine führen könnte. www.volksverpetzer.de/analyse/10-r...

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

I am happy to see this one out - it’s been in the works for years. doi.org/10.1111/mec....

Unique investigation of some errors in long read assemblers. In particular these remarkably chimeric contigs are 😱, if rare.... Improving long read assemblers is definitely the space to be in when it comes to the future of metagenomics, as short reads won't be part of it 😉

Elated and honored to have been awarded an ERC Consolidator Grant! We’ll explore why beetles lose genes — only to rely on symbionts instead 🪲🦠 Incredibly proud of the team and excited for this project to take off w/ some remarkable beetles! @erc.europa.eu www.bio.mpg.de/466825/news_...

The Custom-Lab Institute was featured in Germany's most important journal on the latest news from the life sciences sector, the "Laborjournal"! 😍

📜 A comprehensive all-in-one CRISPR toolbox for large-scale screens in plants 🧑‍🔬 Yanhao Cheng, Yiping Qi, et al. 📔 @theplantcell.bsky.social 🔗 academic.oup.com/plcell/advan... #️⃣ #PlantScience #PlantCRISPR #PlantMethods #PlantGenomics #PlantNGTs #PlantGE #PlantGenomeEditing

New preprint from the lab, describing an approach to enrichment of transcript isoforms for nanopore cDNA sequencing, using CRISPR-Cas9 www.biorxiv.org/content/10.1...

The future of genome editing in plants www.nature.com/articles/s41...

Excited to share this new preprint from the lab, where postdoc Pavan Silva @kptsilva.bsky.social found pathways that control gene amplifications, and thus antibiotic resistance, in Staph aureus! www.biorxiv.org/content/10.1...

Amazing resource for the Arabidopsis and plant community www.cell.com/cell/fulltex...

alright i have my laptop, guess i'm livetweeting the dire wolf preprint. so a quick reminder: this is not yet peer-reviewed, so there's some different expectations re: quality. also let's be clear, i'm a hella biased reader, bc i don't trust the hype they're courting

Fun 🧵on the Colossal Biosciences sponsored preprint (because, folks, that's what it is. Company sponsored preprint-paper with a smash hit fantasy writer on it). Wonderful to see stuff like this on bsky - and I do feel like the whole 80 coding gene edit is a shaky thing to base the claim on. 🧪

@plantevolution.bsky.social encouraging participants to keep (plant) genomics in the context of the real world. @novonordisk.bsky.social

Excited to share our latest preprint about CoExpPhylo: doi.org/10.1101/2025.... Not long ago, Nele excelled at a #Python course for life scientists and acquired crucial skills for this work. #Bioinformatics #DataScience @puckerlab.bsky.social

Excellent resource for plant biologists. I hope the plasmids are in @addgene.bsky.social academic.oup.com/plcell/advan...

I’m very happy to share the published version of our paper on the role of MET1 in wheat 🌾 🧬 It’s been really exciting to discover more about DNA methylation in wheat and it’s huge polyploid genome doi.org/10.1093/jxb/...

Improving hifiasm haplotypes for autopolyploid genome assemblies using constraint programming doi.org/10.1101/2025... Haplotype-resolved assembly of COL40 (Manihot esculenta) line with broad-spectrum resistance against viruses causing Cassava brown streak disease doi.org/10.1101/2024...

CUT&Tag achieves up to 50% recovery of ENCODE ChIP-seq histone acetylation peaks, offering high sensitivity for profiling DNA-protein interactions. PMID:40148272, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-58137-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Our latest work on the Solanum pangenome made the cover @nature.com 🍅🍆🥔 Proud of this collective work with an amazing group of collaborators!

Very proud of our work with Zach Lippman, Jesse Gillis, Joyce Van Eck, @mattbnt.bsky.social, @katiejenike.bsky.social and many others! @jhu.edu @cshlnews.bsky.social www.nature.com/nature/volum...

Do you have transposon-related research cooking, with some cool results you are exciting to share? Start thinking about registering to #EMBOMobileGenome workshop! Nov 4-7 2025 in Heidelberg. One of the historical TE meetings, with a diverse and welcoming community. www.embl.org/about/info/c... 1/3

"Save our Seeds", das Berliner Büro der Anthroposophie-nahen GLS-"Zukunftsstiftung Landwirtschaft", hat eine E-Mail-Aktion an die Verhandlungsführer*innen @spdfraktion.de und Union gestartet. Es geht um die Pläne für eine neue Regulierung für Pflanzen, die mittels CRISPR & Co. gezüchtet wurden. 1/2

Uncalled4 improves nanopore DNA and RNA modification detection via fast and accurate signal alignment. #DNAmodifications @nanoporetech.com #Sequencing #Bioinformatics @naturemethods.bsky.social 🧬🖥️ www.nature.com/articles/s41...

Two fantastic positions in #plantscience: A junior AND a senior group leader position at the Gregor Mendel Institute (GMI), part of @viennabiocenter.bsky.social. Generous core funding, fantastic plant and non-plant colleagues, all in a very livable and beautiful city. www.oeaw.ac.at/gmi/join-us/...

Interested in intronizing coding sequences for enhanced expression in plants? Here’s the protocol: link.springer.com/protocol/10....

Why are certain vancomycin-resistant Enterococcus (VRE) strains taking over hospitals? Emergent lineages make bacteriocin T8—giving them a gut colonization edge over older strains Microbial competition shapes nosocomial evolution Mills et al Nat Microbiol #VRE #AMR www.nature.com/articles/s41...

When I saw this fluorescent green dinosaur at the shops today, it was an instant "must buy". 😅🧪🧬🦕 The #DIYNAFLUOR name and logo started out as a bit of a joke, but ultimately they have really helped catch peoples attention for our open-source DIY DNA fluorometer project.- tinyurl.com/yfh33dsx

Phosphonate aus Waschmitteln werden in Kläranlagen u.a. zu Glyphosat umgewandelt. In welchem Umfang dies geschieht, ist noch nicht geklärt. Doch gemessen an der eingesetzten Menge an Waschmitteln im Vergleich zum Pflanzenschutzmittel dürfte das eine relevante Quelle für Glyphosat in Gewässern sein.

Mixed crop systems are really cool. They provide opportunities to improve land use efficiency, but also give great opportunities to learn how plants respond plastically to local conditions, which may vary quite a bit in mixed crops. Interested in our view? See: www.nature.com/articles/s44...