🚨 New lab paper!🚨 A dream study of mine for nearly 20 yrs not possible until now thanks to NIH 🧠 funding & 1st-author lead @seeber.bsky.social We tracked hippocampal activity as people walked memory-guided paths & imagined them again. Did brain patterns reappear?🧵👇 www.nature.com/articles/s41... - ThreadSky

suthanalab.bsky.social • 9 days ago

🚨 New lab paper!🚨

A dream study of mine for nearly 20 yrs not possible until now thanks to NIH 🧠 funding & 1st-author lead @seeber.bsky.social

We tracked hippocampal activity as people walked memory-guided paths & imagined them again. Did brain patterns reappear?🧵👇

https://www.nature.com/articles/s41562-025-02119-3

Comments

totoroandscience.bsky.social•9 days ago

Oooh! Looking forward to reading. I have a freakishly large set of early memories that we can confirm to less than a year of age, but I’m shit for navigation and downstream spatial memory (it’s gotta be genetic because both run down one side of the family). Thanks!

jeremyrmanning.bsky.social•9 days ago

Such a cool idea and study-- congrats!! 🤩🤓🧠

kiswanson.medsky.social•8 days ago

Very cool research! Congratulations!

alanbince.bsky.social•8 days ago

Inspiring 👏

nicolecrust.bsky.social•8 days ago

WOW. Congrats to you and your team.

neuromusicnerd.bsky.social•8 days ago

Super cool!!

jamesmhyman.bsky.social•9 days ago

This is so cool!

suthanalab.bsky.social•9 days ago

1/ Participants memorized two paths, one with only rightward turns, & one with leftward turns, & walked them from memory. Everyone learned them well, but look at Participant 2…they consistently added an extra turn.

suthanalab.bsky.social•9 days ago

2/ While they walked, hippocampal activity along with motion capture & eye-tracking were recorded.

suthanalab.bsky.social•9 days ago

3/ Theta 🧠 activity increased in bouts right before turns. And Participant 2? That extra turn they took- theta increased there too!

suthanalab.bsky.social•9 days ago

4/ Take a look at the theta bouts (larger 🧠 waves) right before turns. The timing is striking! 👀

suthanalab.bsky.social•9 days ago

5/ Between trials, @seeber.bsky.social had them walk on a treadmill. Sometimes they could think about anything (control trials); other times, they were explicitly told to imagine walking the same paths. 💭

suthanalab.bsky.social•9 days ago

6/ The hippocampus, more than nearby regions, showed shared theta activity between real and imagined walking, but not control trials suggesting 🧠 may be replaying the journey

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