Effects of psilocybin in mice depend on context of administration!
Psilocybin [5 mg/kg (> 5-10x higher than human dose)] has anxiolytic effects in male and female mice, which were ameliorated (m) or attenuated (f) by concurrent restraint stress.
https://www.sciencedirect.com/science/article/pii/S0028390824004490?casa_token=4mmo79FP-8wAAAAA:qNwTYfwXC-FTy6VShuPmoXIdu-i0bdl88iXc5svrRw0BhbvLFnhsZnBpjTEdo_aYlG6wn69mamA
Psilocybin [5 mg/kg (> 5-10x higher than human dose)] has anxiolytic effects in male and female mice, which were ameliorated (m) or attenuated (f) by concurrent restraint stress.
https://www.sciencedirect.com/science/article/pii/S0028390824004490?casa_token=4mmo79FP-8wAAAAA:qNwTYfwXC-FTy6VShuPmoXIdu-i0bdl88iXc5svrRw0BhbvLFnhsZnBpjTEdo_aYlG6wn69mamA
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