sequencemyneuro.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Yuge paper! Long awaited CryoEM structures for seven psychedelics.

submitted 10 days ago • 0 comments

I'm not sure that our study necessarily implies that one should not average trials - averaging will always have its place. However, our results do show that there is substantial and meaningful variability across trials that is lost when averaging. #neuroscience #neuroskyence

submitted 33 days ago • 0 comments

We’ve launched a new clinical trial exploring the efficacy of psilocybin therapy for anorexia nervosa in young adults (age 18 to 25)! Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.

submitted 34 days ago • 1 comment

This is so cool! Love to see it

submitted 44 days ago • 0 comments

Super cool work showing that pleiotropic genes increase trans-diagnostic risk for multiple categories of psychiatric disorders! www.cell.com/cell/abstrac...

submitted 47 days ago • 0 comments

Of all known technologies, I am most excited about Raman Spectroscopy. Its the closest thing to the Star Treck Tricorder that I'm aware of. Lasers wiggle molecules, and you measure the wiggles to know what it is. Imagine a world where we can scan just about anything and determine its composition?

submitted 52 days ago • 0 comments

Reminder: You can always submit a grant late and include a cover letter saying why. NIH receipt and referral may take it. Or not. If you end up missing deadline because of these Commons access issues, there is this potential save move.

submitted 55 days ago • 2 comments

I’ll be speaking at the upcoming International Society of Research on Psychedelics (ISRP) virtual conference on March 7, 2025! 🌐 ✨ 24 presentations from psychedelic researchers. ✨ Cutting-edge insights in psychedelic science. ✨ Register here today! #Psychedelics #PsychedelicResearch #ISRP2025

submitted 97 days ago • 1 comment

Open to all interested in psychedelics, the upcoming virtual ISRP meeting! Register now and catch up on the latest breakthroughs!

submitted 64 days ago • 0 comments

Today is the last day for early bird registration for @ISRPsychedelics! Are psychedelics anti-inflammatory? Come to my talk to find out what we know.

submitted 58 days ago • 0 comments

Are psychedelics anti-inflammatory? A systematic review and meta-analysis of studies examining the immunomodulatory effects of serotonergic psychedelics Come see me present at the International Society for Research on Psychedelics on March 7th! (online) www.isrpsych.org/conferences

submitted 66 days ago • 1 comment

Would love to chat about this with some bioethicists sometime! It’s a very interesting and unfortunately touchy topic that we really need to discuss out in the open! #bioethics @trpr-ucsf.bsky.social

submitted 68 days ago • 0 comments

Home of the?

submitted 70 days ago • 0 comments

The (concise) core of my critique of MAPS/Lykos' MDMA-assisted therapy model is now published as a bioethics commentary in AJOB, titled "Focused Bodywork as Facilitated Communication: Cautionary Perspectives on Touch in Psychedelic Therapy": www.tandfonline.com/doi/full/10....

submitted 72 days ago • 1 comment

🚨 Save the Date! 🚨 I'm speaking about 4-HO-MiPT analogs at the upcoming International Society of Research on Psychedelics (ISRP) virtual conference on March 7, 2025! 🌐 ✨ 24 presentations ✨ Register here today - www.isrpsych.org/store #Psychedelics #PsychedelicResearch #ISRP2025

submitted 74 days ago • 0 comments

How the brain gets rid of its chemical waste through the glymphatics during sleep, via blood vessel oscillations, regulated by norepinephrine. Impeded by Ambien! www.cell.com/cell/abstrac... www.science.org/content/arti...

submitted 80 days ago • 16 comments

Big co-1st/corresponding author paper just published in @JAMAPsychiatry! I just can't thank our team enough for their unwavering support on this project. Modifying Informed Consent to Help Address Functional Unmasking in Psychedelic Clinical Trials jamanetwork.com/journals/jam...

submitted 81 days ago • 2 comments

Effects of psilocybin in mice depend on context of administration! Psilocybin [5 mg/kg (> 5-10x higher than human dose)] has anxiolytic effects in male and female mice, which were ameliorated (m) or attenuated (f) by concurrent restraint stress. www.sciencedirect.com/science/arti...

submitted 83 days ago • 0 comments

Woah.. surprised to see this, but obviously it should be addressed in our public health policies.. my understanding is that topical fluoride on the teeth is highly effective at reducing cavities, but systemic fluoride is less useful in that way.. so keep it in toothpaste, but not water?

submitted 83 days ago • 0 comments

Share and enjoy.

submitted 84 days ago • 1 comment

academic.oup.com/brain/advanc...

submitted 84 days ago • 0 comments

Out today: cross-species improvement of cognitive flexibility www.science.org/doi/10.1126/... The TLDR: remember when we improved human cognition with deep brain stimulation? (pubmed.ncbi.nlm.nih.gov/34725508/) Well, now we did it in rats, and it works the same! Specifically... 1/

submitted 102 days ago • 2 comments

Hi everyone, we have published a new paper showing that #psilocybin increases emotional #empathy in patients living with depression for at least two weeks after a single administration. If you are interested in #psychedelics and #social cognition, take a look here: www.nature.com/articles/s41...

submitted 102 days ago • 2 comments

Terrific! Paywalls are disappearing! No more 12 month embargo between when NIH funded work appears in a journal and when it becomes accessible to all (as of December 2025). www.nih.gov/about-nih/wh...

submitted 102 days ago • 11 comments

This is why psychedelics won’t ever make it as they are in the field. They are not profitable if you can give something once every 6 months, or just once, period. We need to be fighting to change our healthcare system, our drug policy, our regulatory agencies.

submitted 102 days ago • 1 comment

I got to thinking about the Insel years and went over to RePORTER to see some things drugmonkey.scientopia.org/2024/12/17/t...

submitted 103 days ago • 0 comments

Yep. ALL journals are predatory journals.

submitted 103 days ago • 1 comment

This is such a great paper - a genuinely novel perspective, plus so well argued and engagingly written. 10/10.

submitted 103 days ago • 0 comments

I created a Mitochondrial Psychobiology starter pack. If you're into that sort of thing, add yourself to the list and follow the other mitchondriacs here to help build the community! go.bsky.app/KdP8Vp

submitted 104 days ago • 0 comments

Do serotonergic psychedelics (like LSD, psilocybin, and 2C-B) all induce the same acute changes in brain activity? Our research in rats says they have some common features but also some distinctly different ones. The images below are from our newest preprint.

submitted 105 days ago • 2 comments

These great studies show stress-induced synaptic remodeling linked to narrowed behavior, but can you point me to other examples? pubmed.ncbi.nlm.nih.gov/19644122/ pubmed.ncbi.nlm.nih.gov/16870732/

submitted 107 days ago • 0 comments

New blog post! I figured out how to make some really nice visualisations of brain networks using Gephi, and wrote a tutorial on how to do it here: medium.com/@m.b.wall/ho...

submitted 108 days ago • 3 comments

hi! still growing this list of amazing peeps! go.bsky.app/32Le3SU

submitted 125 days ago • 2 comments

Published in JAMA with #CCRdownunder: In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com ja.ma/3BovM5v

submitted 111 days ago • 0 comments

NIH funding generated $2.46 for every $1 funded in 2023. Important info for scientific advocacy in the years ahead- science is a quantifiable investment, not just a cost. H/t to @nicolecrust.bsky.social for sharing! #AcademicSky #PsychSciSky #NeuroSkyence www.fiercebiotech.com/research/rep...

submitted 133 days ago • 2 comments

The epigenetic effects of childhood adversity can have both adverse and protective effects DNA methylation mediates the link between adversity and depressive symptoms | Nature Mental Health www.nature.com/articles/s44...

submitted 115 days ago • 0 comments

This is so important. www.nature.com/articles/s41...

submitted 116 days ago • 0 comments

Psychopharmacology gets lots of criticism from psychotherapy/adjacent folks. But if someone could send me therapy trials that 1. Are double-triple blind 2. Carefully document/report AEs 3. Pre-register an SAP with ITT I would appreciate. I will wait ….

submitted 121 days ago • 4 comments

Surprisingly (relative to previous work on other psychedelics), Ayahuasca acutely enhances hippocampal-dependent memory and does not increase rates of false memories! journals.sagepub.com/doi/full/10....

submitted 117 days ago • 0 comments

Great podcast on the neurobiology of stress with Rosemary Bagot of McGill! youtu.be/g5_0nG9nQTo?...

submitted 117 days ago • 0 comments