Reduced phospholipid species containing polyunsaturated fatty acids (PUFAs) in C9 #ALS/FTD Drosophila, iPS cell-derived neurons, and postmortem #FTD brain tissue; increasing PUFA levels in neurons is protective in fly and cellular models 🧪🧠

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https://www.nature.com/articles/s41593-025-01889-3

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