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Widespread cofluctuations in the low-frequency range between resting-state global fMRI signals, EEG activity, and a host of peripheral autonomic signals spanning cardiovascular, pulmonary, exocrine and smooth muscle systems 🧪🧠 www.nature.com/articles/s41...

submitted 2 days ago • 0 comments

A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠 @bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social www.nature.com/articles/s41...

submitted 5 days ago • 0 comments

A competitive disinhibitory network for robust optic flow processing in Drosophila 🧠🧪 www.nature.com/articles/s41...

submitted 10 days ago • 0 comments

Single-cell genotyping and transcriptomic analysis reveals cell-type specific and non-autonomous effects of mTOR pathway mutations in mosaic focal cortical dysplasia type II (FCDII) 🧠🧪 www.nature.com/articles/s41...

submitted 11 days ago • 0 comments

Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks that can describe mechanisms of cortical development, centering on peak stages of neurogenesis 🧠🧪 www.nature.com/articles/s41...

submitted 12 days ago • 0 comments

Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes 🧪🧠 www.nature.com/articles/s41...

submitted 13 days ago • 0 comments

Chief Editor Shari Wiseman @shariwiseman.bsky.social will be at the @keystonesymposia.bsky.social Interoception meeting in Seattle this week!

submitted 19 days ago • 0 comments

Dynamics of glia and neurons regulate homeostatic rest, sleep and feeding behavior in Drosophila 🧪🧠 www.nature.com/articles/s41...

submitted 20 days ago • 0 comments

🥳Please join us in welcoming Will Olson @will-olson.bsky.social to the Nature Neuroscience Editorial team! Will is handling systems, computational, and theoretical neuroscience and is based in the Philadelphia office!

submitted 24 days ago • 0 comments

A Review on #microglia heterogeneity, modeling and cell-state annotation in development and neurodegeneration www.nature.com/articles/s41...

submitted 24 days ago • 0 comments

Two-photon imaging of #GABA release in the inner plexiform layer of male and female mice retinae (8–16 weeks old) reveals over 40 different GABA-releasing neuron types 🧪🧠 www.nature.com/articles/s41...

submitted 25 days ago • 0 comments

Two-photon imaging in awake bats reveals that the inferior colliculus encodes vocalization categories as categorical primitives—spatially clustered, category-selective neurons that enable early, efficient, and structured processing @kishoreneuro.bsky.social www.nature.com/articles/s41...

submitted 26 days ago • 0 comments

Inactivation of the ventral subiculum doesn't change existing schema cells in the orbitofrontal cortex (OFC) but aids their formation during new learning www.nature.com/articles/s41...

submitted 27 days ago • 0 comments

Nature Genetics is looking to hire a new editor! Come join our team and help publish the most exciting research in genetics and genomics! Deadline is April 25th. springernature.wd3.myworkdayjobs.com/en-US/Spring...

submitted 30 days ago • 0 comments

A Perspective on integrating multimodal data to understand cortical circuit architecture and function @alleninstitute.bsky.social www.nature.com/articles/s41...

submitted 31 days ago • 0 comments

Single-nucleus transcriptome and chromatin accessibility analyses to compare neurons across three- to six-layered cortical areas of adult mice and across tetrapod species 🧪🧠 @sarazeppilli.bsky.social www.nature.com/articles/s41...

submitted 31 days ago • 0 comments

Task-free functional and structural magnetic resonance imaging data from 33,250 individuals at 32 weeks of postmenstrual age to 80 years from 132 global sites 🧠🧪 www.nature.com/articles/s41...

submitted 33 days ago • 0 comments

Our April issue is now live! www.nature.com/neuro/volume...

submitted 34 days ago • 0 comments

Slow, facilitating inhibitory connections between #serotonin neurons in the dorsal raphe, refuting autoinhibition theories. This recurrence drives winner-take-all effects and nonlinear processing of threat-related inputs 🧠🧪 www.nature.com/articles/s41...

submitted 37 days ago • 0 comments

Insight into place field formation in general, and specifically how the #hippocampus adaptively remaps for flexible goal-directed navigation 🧪🧠 www.nature.com/articles/s41...

submitted 38 days ago • 0 comments

DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning @boazmohar.bsky.social har.bsky.social @rhodamine110.bsky.social mine110.bsky.social @forna.bsky.social @hhmi.org www.nature.com/articles/s41...

submitted 39 days ago • 1 comment

A speech-neuroprosthetic paradigm to restore naturalistic spoken communication to people with paralysis www.nature.com/articles/s41...

submitted 40 days ago • 0 comments

Whole-brain projections of over 7,000 hypothalamic neurons expressing distinct neuropeptides in male mice, identifying 2 main classes and 31 types using single-neuron projectome analysis 🧪🧠 www.nature.com/articles/s41...

submitted 41 days ago • 0 comments

Identification of distinct neural ensembles in the adult mouse spinal cord encoding mechanical and heat #pain 🧠🧪 @patrikernfors.bsky.social www.nature.com/articles/s41...

submitted 44 days ago • 0 comments

Human medial temporal lobe neurons and recurrent neural networks (RNNs) exhibit theta oscillations and phase-specific firing during working memory for temporal order. But, firing order does not match item order 🧠🧪 www.nature.com/articles/s41...

submitted 45 days ago • 0 comments

Behavioral timescale synaptic plasticity (BTSP), not Hebbian spike-timing-dependent plasticity (STDP), explains heterogenous place field shifting in the mouse hippocampus 🧠🧪 www.nature.com/articles/s41...

submitted 47 days ago • 0 comments

Behavior and #dopamine responses track prospective, but not retrospective, contingency, which is explained by temporal difference (TD) learning models @mhburrell.bsky.social @naoshigeuchida.bsky.social @harvardmcb.bsky.social www.nature.com/articles/s41...

submitted 48 days ago • 0 comments

A disease-associated subset of capillary endothelial cells (ECs) in cortex samples from individuals with neurodegenerative disease exhibit loss of nuclear TDP-43; TDP-43 disruption in human and mouse ECs replicates these alterations 🧪🧠 @patrickmurphy.bsky.social www.nature.com/articles/s41...

submitted 51 days ago • 0 comments

Expectation-driven sensory adaptations support enhanced acuity during categorical perception in European starlings 🧠🧪 @timsainburg.bsky.social www.nature.com/articles/s41...

submitted 52 days ago • 0 comments

Sympathetic and parasympathetic subtypes of body-first Lewy body disease observed in postmortem tissue from prediagnostic individuals 🧠🧪 www.nature.com/articles/s41...

submitted 54 days ago • 0 comments

Striatal cholinergic interneurons act at nAChRs to depress #dopamine release, supporting an inverse scaling of dopamine release according to cholinergic activity 🧠🧪 @stephcragg.bsky.social @craggasap.bsky.social @oxforddpag.bsky.social www.nature.com/articles/s41...

submitted 54 days ago • 0 comments

Neuronal mitochondrial respiratory complex IV deficiency in rats is sufficient to cause a number of #ALS-like phenotypes, including cytosolic TDP-43 redistribution, selective motor neuron loss, and paralysis www.nature.com/articles/s41...

submitted 55 days ago • 0 comments

Even while processing current experiences, people reactivate old ones and re-encode them (shown using intracranial EEG), turning thoughts into memories. www.nature.com/articles/s41...

submitted 58 days ago • 1 comment

During foraging with reward-threat conflicts in mice, #dopamine modulates two competing neuron types in the striatum for flexible threat-coping, from initial threat avoidance to eventual overcoming of the threat www.nature.com/articles/s41...

submitted 59 days ago • 0 comments

A model of compositional state spaces in the #hippocampus shows latent learning and rapid generalisation, and predicts the emergence of place responses in replay – which is discovered empirically in an existing dataset 🧪🧠 www.nature.com/articles/s41...

submitted 61 days ago • 0 comments

A trio of Comments about #consciousness from leading thinkers in the field First, What makes a theory of consciousness unscientific? www.nature.com/articles/s41...

submitted 61 days ago • 1 comment

Our March issue is now live! www.nature.com/neuro/volume...

submitted 62 days ago • 0 comments

IL-1- and IL-6-related systemic inflammation in #COVID19 is associated with #microglia dysfunction, neurovascular inflammation, and focal neuropathologies 🧪🧠 www.nature.com/articles/s41...

submitted 62 days ago • 1 comment

Neuronal somatic mutations are increased in multiple sclerosis lesions 🧪🧠 www.nature.com/articles/s41...

submitted 65 days ago • 0 comments

A genome-wide CRISPR screen for regulators of astrocyte inflammation identified CLEC16A, linked to MS susceptibility, as a suppressor of NF-κB signaling; CLEC16A promotes mitophagy, and ablating it in astrocytes worsens pathology in an MS model 🧪🧠 www.nature.com/articles/s41...

submitted 66 days ago • 0 comments

And this year @brainprize.bsky.social goes to... Professors @michellemonje.bsky.social and Frank Winkler for their work in Cancer Neuroscience. Such an imporant and growing field of research!

submitted 67 days ago • 0 comments

Lateral inhibition from parvalbumin neurons in mouse primary visual cortex reduces sensitivity to contrast; lateral inhibition from somatostatin neurons changes the gain of contrast sensitivity 🧪🧠 @haiderlab.bsky.social @gtresearchnews.bsky.social s.bsky.social www.nature.com/articles/s41...

submitted 67 days ago • 0 comments

Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury (#TBI), enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg–#microglia crosstalk in mice 🧪🧠 www.nature.com/articles/s41...

submitted 68 days ago • 0 comments

Astrocytic cannabinoid receptor 1 promotes resilience to stress in males by dampening stress-induced blood–brain barrier alterations 🧪🧠 @caromenard666.bsky.social www.nature.com/articles/s41...

submitted 72 days ago • 0 comments

Reduced phospholipid species containing polyunsaturated fatty acids (PUFAs) in C9 #ALS/FTD Drosophila, iPS cell-derived neurons, and postmortem #FTD brain tissue; increasing PUFA levels in neurons is protective in fly and cellular models 🧪🧠 @adrianisaacs.bsky.social www.nature.com/articles/s41...

submitted 73 days ago • 0 comments

PTEN mutations impair CSF dynamics and cortical networks by dysregulating periventricular neural progenitors 🧪🧠 www.nature.com/articles/s41...

submitted 74 days ago • 0 comments