Thrilled to share our latest @cp-cell.bsky.social.
We present VICAR (VIral-induced Centromeric DNA Amplification and Recognition), a new defense system to detect viruses in the nucleus based on nuclear cGAS.
https://www.cell.com/cell/abstract/S0092-8674(25)00556-2
We present VICAR (VIral-induced Centromeric DNA Amplification and Recognition), a new defense system to detect viruses in the nucleus based on nuclear cGAS.
https://www.cell.com/cell/abstract/S0092-8674(25)00556-2
Comments
I just seen this and I will read in detail, but... I wonder,
what is the advantage for viruses to target the centromere proteins? they inhibit silencing machinery there? hmm 🤔.. is that known?