Archaeal SMCs organize Thermococcus kodakarensis genome into TAD-like domains via DNA loop extrusion, influenced by TrmBL2. Insights into chromosomal structuring! #GenomicDiscovery PMID:39971902, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-56197-y #Medsky #Pharmsky #RNAsky 🧪