This is wow. I note there is limited plex but there is a sort of massive sampling / imputation game/analysis to do here from single cell / single nuclei to 2D samples to 3D samples - sampling in this order - build the 3D framework in reverse
Yes sounds like a fun game to play! Mouse brains from inbred strains are sufficiently anatomically similar that you can also ”simply” multiplex by using more animals.
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