For your reading pleasure, I wrote up an image-heavy, not-comprehensive post on Doomsday Machines about depicting nuclear war in video games, with some thoughts on "Nuclear War" (1989) and "DEFCON" (2006). https://open.substack.com/pub/doomsdaymachines/p/strange-games?r=7tc7c&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
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https://www.youtube.com/watch?v=xCOfS3fNZhc
https://journals.sfu.ca/loading/index.php/loading/article/view/130
but as far as I could read it it seemed effects were very minimal, which surprised me-- I found it very unsettling