So many new followers!! Hi folks, nice to meet you all. 🖤 I'll introduce my core research interests by showing you some of the work we've done in recent years on the conceptualization, measurement, modeling, and theories of mental health (problems). 🧪 #PsychSciSky #psychiatry #statssky 🧵 - ThreadSky

eikofried.bsky.social • 95 days ago

So many new followers!! Hi folks, nice to meet you all. 🖤

I'll introduce my core research interests by showing you some of the work we've done in recent years on the conceptualization, measurement, modeling, and theories of mental health (problems).

🧪 #PsychSciSky #psychiatry #statssky

🧵

Comments

dan84sthl.bsky.social•95 days ago

I'm a big fan of your work! 👏✨ I've been following your blog for years.

eikofried.bsky.social•95 days ago

Hi Dan :)

roelvis.com•95 days ago

Hey doc, what's your take on this study & corporations adding the chemical in our consumer products (specifically those intended for children)?

https://pmc.ncbi.nlm.nih.gov/articles/PMC5289565/

https://trumoo.com/products/chocolate-whole-milk-plastic-gallon/

eikofried.bsky.social•95 days ago

I don’t work on the topic. My understanding is that this is a bigger problem in the US than in the EU which has stricter regulations

r3rt0.bsky.social•95 days ago

that's really interesting! thank you :)
Would it be possible that the diagnosis threshold does not only depend on the person, but on the environment? F. ex., that the same 'level' of difficulties could be considered 'pathological' in one environment, but tolerated (hence, normal) in another? (1/2)

r3rt0.bsky.social•95 days ago

Would it be possible that the same level of 'phenotype' would lead to difficulties in one society, but not in another? Or that it would be tolerated in a high SES context, but not in a low SES one? (2/2)

eikofried.bsky.social•95 days ago

Diagnosis threshold formally often doesn’t take environment into account but of course well trained clinicians do. There was considerable drama around an update a decade ago to diagnostic criteria of depression.

Previously, you didn’t get a diagnosis even if you met criteria when …

eikofried.bsky.social•95 days ago

… you had lost a loved on recently. Makes sense, few people sleep well or are happy or can focus well in these periods.

Unfortunately they removed this “bereavement exclusion” from dsm-4 to dsm-5.

But still, some clinicians of course will take this and other aspects into account.

eikofried.bsky.social•95 days ago

Goes back to the question what the purpose of a diagnosis is and why we diagnose. To indicate people who aren’t well? Making sure their treatments get covered? To help better monitor people because they’re now in the system? Etc.

r3rt0.bsky.social•95 days ago

I always kept in mind what S. Baron-Cohen said for the autistic quotient (AQ): "Such a high score on the AQ however does not mean an individual has AS or HFA, since a diagnosis is only merited if the individual is suffering a clinical level of distress as a result of their autistic traits" 1/2

youngpilots.bsky.social•95 days ago

I had some time so I'm rereading Jung.

dameg.dev•95 days ago

Interesting. Is there any effect on someone who is incorrectly “warned”? As in, can misplaced proactive treatment/warning have a non-negligible outcome?

eikofried.bsky.social•95 days ago

In the same way you can under- or overdiagnose people, and under- or overtreat people, you have false positives and false negatives when building a warning system. All of these can be very problematic.

stefanieboyles.bsky.social•95 days ago

Big fan! Incredible work, Eiko!

owenmuir.bsky.social•95 days ago

Welcome.

galacticmonk.com•95 days ago

Classified agencies have neuroweapons that can emulate mental health symptoms. A lot of people are finding out.

eleanorchats.bsky.social•95 days ago

Great to find you again on here! I always enjoy reading about your work and have drawn on it in teaching research methods to clinical psychology trainees.

mikeneuland.bsky.social•95 days ago

Nice to meet You 🖖

yooonity.bsky.social•95 days ago

I’m new here, bipolar/ASD/anxiety, and it’s so great to feel welcome and in good company (unlike that “other” place). If more people understood the role trauma plays in mental health, the world would be a better place!

eikofried.bsky.social•95 days ago

1/ What *are* mental disorders?

I view them as systems of biological, psychological, and social variables. Mental health problems emerge from this system, which is why system and network science are so important for better understanding and treating them.

https://journals.sagepub.com/doi/10.1177/09637214221114089

eikofried.bsky.social•95 days ago

2/ If we take this idea of sytems seriously, this means we want to map out mental health problems as systems.

Statistical tools from systems & network science are useful here.

We wrote an introduction about these methods here for applied researchers:
https://www.nature.com/articles/s43586-021-00055-w

eikofried.bsky.social•95 days ago

3/ This also means we want to collect *dynamic* data, because mental health systems are dynamic & changing.

One way to do this is via ecological momentary assessment, querying participants often on their phone.

Here a recent intro @bsiepe.bsky.social on how to work with such data:

eikofried.bsky.social•95 days ago

4/ The idea of bistable (healthy vs ill) mental health systems also offers crucial opportunities to forecast onset of disorders via early warning signals & tailor preventions!

This is what we do in my large WARN-D study, building an early warning system for depression.

Protocol:

eikofried.bsky.social•95 days ago

5/ You can find more on the WARN-D study here:

- 4 minute intro video: https://www.youtube.com/watch?v=7bN5kkRbUdw
- website: https://warn-d.com
- brilliant team: https://warn-d.com/warn-d-team/
- OSF project hub (all papers, code etc): https://osf.io/frqdv/

eikofried.bsky.social•95 days ago

6/ Related to the question what mental disorders are is the topic of how to accurately measure mental illness.

Here an overview paper of the big challenges the field is facing, with a focus on depression.

https://www.nature.com/articles/s44159-022-00050-2.epdf?sharing_token=QtAhlhtoUIjYeFJD_4FIvdRgN0jAjWel9jnR3ZoTv0NfrTIPYUaDxFHewbRT1HdShI9oXDSjqkh6oJvqY_vHeeaHAERvI9aO-nZD9J1zXfGYk7Odf6A2SbSsHoKJTkx8OP3fD4vua1HtCYiWMpiDCN1bLJivwONRdPlKHiLP0AY%3D

quantpsychiatry.bsky.social•95 days ago

I've been thinking this "bistable network" idea in the context of "periodic catatonia" from the Wernicke-Kleist-Leonhard school of psychiatric nosology (dk if you're familiar but it's actually much bigger in Germany/EU). Fascinating phenotype--know it?
https://link.springer.com/article/10.1007/BF02193085

quantpsychiatry.bsky.social•95 days ago

In particular, given the many different manifestations of catatonia and it's "cyclic" nature in this condition (alternating hypo/hyper-kinetic phases) there's real potential for a good network model of symptoms feeding into an explanation of how it works (which I think is rn a big "???").

mariannhardey.com•95 days ago

Appreciate you being here 😌

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