Interesting observations. Wonder if cerebral vasoconstriction could be related to functional vascular diseases such as Raynaud's syndrome, acrocyanosis and erythromelalgia. Much to learn.
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OI syndromes in ME or LC: HR & RR are frequently normal despite significant drops in CBF. This often leads to the incorrect conclusion that there is nothing hemodynamically abnormal & thus no explanation or treatment needed. Review CBF assessment OI www.ahajournals.org/doi/10.1161/...
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https://pubmed.ncbi.nlm.nih.gov/39846717/