Prenatal stress effects on the placenta. Maternal stress is a critical factor in the long-term health of offspring. A recent study (below) profiled the effects of prenatal stress on DNA methylation + gene expression in rat placenta & fetal brain. 🧪🧠🐀 #neuroskyence www.nature.com/articles/s41... - ThreadSky

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auditorynerves.bsky.social • 24 days ago

Prenatal stress effects on the placenta.

Maternal stress is a critical factor in the long-term health of offspring. A recent study (below) profiled the effects of prenatal stress on DNA methylation + gene expression in rat placenta & fetal brain.
🧪🧠🐀 #neuroskyence
https://www.nature.com/articles/s41593-025-01887-5

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auditorynerves.bsky.social•24 days ago

Open access 🧪 study here:

Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations (in rats)
#neuroskyence
https://www.nature.com/articles/s42003-024-07444-3

clairecass.bsky.social•24 days ago

I know it’s adding to the sum of knowledge and that’s great… but my first thought was great now I have to worry and feel guilty about being stressed as a pregnant person. In itself an immediate stress injection. It’s like someone screaming “CALM DOWN”.

auditorynerves.bsky.social•24 days ago

Not easy for anyone these days ... 😔

hermgamma.bsky.social•23 days ago

Pregnancies are always a bit stressful and the animals in the experiment probably had a very high dose. Do you think that some of the changes are a means of a mother preparing her offspring for a difficult environment as opposed to being purely pathological?

auditorynerves.bsky.social•23 days ago

Not my area, but that seems an entirely reasonable suggestion, experience influencing offspring resilience.

deborah-foster.bsky.social•23 days ago

📌

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