Thx for sharing our work. It is always a fun exercise to separately analyze the generative process and the statistical model that's applied on top of the generative process.
Not all DEGs are the same!
Not all DEGs are the same!
Reposted from
Will Townes
@epigenci.bsky.social makes a pretty convincing case for pseudobulk (as opposed to GLMMs) in multi-sample single cell studies here: doi.org/10.1093/bioi... . #bioinformatics
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