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epigenci.bsky.social
PhD Student at UMich Statistics. The account mostly trashes about US urban planning and infrastructure. Probability, Statistics, and Evolutionary Biology. https://hanbin973.github.io
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Waiting for probgen so badly because I'm city addicted and I haven't been to an urban area for at least a month.

Did the East Germans just hold an independence vote?

Just out in @naturehumbehav.bsky.social ! We focused on the causes & impact of self-report error in the UK Biobank. We found that reporting error does not occur at random, is not independent of other participation behaviours, and can complicate the interpretation of GWA findings shorturl.at/N4Qc6

great quarto/revealjs tips www.avonture.be/blog/quarto-...

Absolutely love to see this! Cambridge should allow more people to live near its jobs, parks, shops, restaurants, & public transit. (No, that doesn’t include historic parking lots.) Allowing midrise housing citywide is a great start.

I'm glad that the Attorney General of the state where I live is a lesbian and a civil rights lawer amongst the current crisis happening in this country.

Europeans complain about Americans for working too hard, but honestly, you don't have anything to do in your meantime cus half of the Americans live in the middle of nowhere. There's a reason why my office mates (including myself) always show up in the office in the weekends.

I have a suspicion that priors of Bayesian analysis of genomic data represent some aspects of an evolutionary process underlying the generative process.

"NIH admit freezing is illegal, will resume issuing grants" popular.info/p/breaking-n...

At last, I can request a 1600$+ reimbursement to the school.

I wonder when the administration will start complaining about running clinical trials in the US because it's risking Americans' health for a treatment that could potentitally benefits everyone else.

Our site appears to be down, but we are casting Aaron King's seminar at https://buff.ly/3QeJb3Z now!

Low accessibility to healthcare in the US must be a major reason for why people are less interested in how many medical breakthroughs came out of NIH funded researches. No matter what is brought to the market by science, people just can't afford it.

It's interesting, I recorded two interviews this week, and both asked me to comment on group selection vs inclusive fitness. I was diplomatic, but honestly, I think the anti-group selection dogma stemming from the 60s is pretty embarrassing, highlighting a surprising lack of critical thinking.

Oh! I love the result. The forward KL divergence objective that is popular in ML-based amortized Bayesian inference is convex => it is globally convergent! (given that the solution exists). openreview.net/forum?id=8x4...

Trump megadonor Steve Wynn has filed a petition asking the Supreme Court to overturn the landmark 1964 decision in New York Times v. Sullivan, which protects the media's ability to aggressively cover public officials. www.supremecourt.gov/DocketPDF/24...

www.illinoisattorneygeneral.gov/news/story/a...

Really looking forward for an upcoming preprint so that I can just drop the article instead of writing long threads.

Think of a polygenic score you care about. Are direct genetic effects driving variation among people in this predictor? Or perhaps other, confounding factors? We at the @arbelharpak.bsky.social & @docedge.bsky.social Labs developed a method to tackle this question. [1/n]

Publishers take thousands of dollars of APC but ask me to do the typesetting.

I dont buy the argument that Reagan is better than Trump. Trump literally grew out of the soil on which Reagan cultivated. If it wasn't for Reagan, not only the US but the whole world would have been a better place.

How accurate are those extreme tail probabilities?

I was surprised by coding autopilots while writing up a lab material for a class. I'm writing a solution for questions provided by the instructor and Google Colab (probably Gemini?) instantaneously returns a correct answer as soon as I type 'variable ='.

Thx for sharing our work. It is always a fun exercise to separately analyze the generative process and the statistical model that's applied on top of the generative process. Not all DEGs are the same!

I complained to much about finishing projects that began in my previous affiliation. Then I just saw our postdoc and...

Is there a markdown-based tool to create posters? something like Quarto for slides in markdown.

Nah it is now clear that the new administration will not add anything for pedestrians.

Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵

We are thrilled to share that our paper entitled "Inference of the demographic histories and selective effects of human gut commensal microbiota over the course of human history" is officially out in MBE! academic.oup.com/mbe/advance-...

Friends, we have a school-wide search for an open rank faculty as mentor professor. It is a unique position that can be hired in a variety of departments across the school. Please check it out and share widely. recruit.apo.ucla.edu/JPF10062

BREAKING A judge has temporarily blocked Trump’s order to end birthright citizenship. Judge Coughenour said: “I've been on the bench for over four decades. I can’t remember another case where the question presented is as clear as this one. This is a blatantly unconstitutional order.”

I really feel these kinds of studies are not conceptually well founded or informative in any actionable sense (especially if they ignore the fact the relevant gene expression may have been in development).

My bluesky debut! One week to the submission deadline for SMBE 2025, Beijing 20-24 July smbe2025.scimeeting.cn @anaignatieva.bsky.social and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.

Wild to me that there are people who work in academics who just have no desire to learn about anything

There is no such thing as a natural classification of biological entities. All biological classifications exist to serve a particular biological theory and are pointless outside the context they're supposed to serve.

Race is not biological, but racism has biological consequences. Genetic differences re:ancestry do not signify distinct biologies, just can *sometimes* alter the probability of observing specific effects. The two are not exchangeable. To treat them as the same is lazy & disingenuous.

Trump really confirmed that sex and gender are constructive lol It's the government that decides how many gender/sex are there!

Cleared a revision that haunted me for an year. Now moving forwards to meet a March 1st deadline.