These models capture the change in gene expression variation that is specific to the case condition, as well as the variation that exists in both the case and control conditions
This work from Caroline Uhler's group both uses info on interventions and also allows for unobserved variables. Would love to see this get more attention! https://arxiv.org/pdf/2307.06250
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From @hjp.bsky.social lab
These models capture the change in gene expression variation that is specific to the case condition, as well as the variation that exists in both the case and control conditions
https://arxiv.org/pdf/2307.06250