Unique investigation of some errors in long read assemblers.
In particular these remarkably chimeric contigs are 😱, if rare....
Improving long read assemblers is definitely the space to be in when it comes to the future of metagenomics, as short reads won't be part of it 😉
In particular these remarkably chimeric contigs are 😱, if rare....
Improving long read assemblers is definitely the space to be in when it comes to the future of metagenomics, as short reads won't be part of it 😉
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We've also seen this, using a spike-in control bacterium with plasmid (6.8kbp). metaFlye is overly careful and gives fragmented assemblies, while metaMDBG is overly eager and generates concatenations