Specifically for In-N-Out, good reasons to not give them business is the owners, long known to be conservatives, were against the Covid vaccine mandates, are anti-LGBTQ, and later insisted employees not wear masks so customers could "see their smiles".

https://datebook.sfchronicle.com/food-drink/shocked-by-in-n-out-burgers-anti-vaccine-mandate-stance-you-shouldnt-be