Since the MYD88/TRIF double knockout debacle 15 years ago, which revealed that their absence doesn’t impact antibody production, the entire adjuvant field has collapsed. You can't fit a square peg into a round hole.

#immunology
Reposted from Waggoner Lab
Review @sciimmunology.bsky.social @tianyangmao.bsky.social
Linking vaccine adjuvant mechanisms of action to function
www.science.org/doi/10.1126/...

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